Gene Information

Name : leuS (GTNG_2742)
Accession : YP_001126832.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 2859590 - 2862025 bp
Length : 2436 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGGAGGAGTGCGACGATGAGTTTCAACCATCGCGAAATTGAGAAAAAGTGGCAGGATTATTGGGAACAGCATAAAAC
GTTCCGCACCCCGGATGAAAGCGATAAACCGAAGTTTTACGTGTTGGATATGTTTCCGTATCCGTCTGGCGCTGGCTTGC
ACGTCGGCCATCCGGAAGGGTATACGGCGACCGATATTTTGGCGCGCATGAAGCGGATGCAAGGGTACAATGTCCTTCAC
CCGATGGGGTGGGACGCGTTCGGATTGCCGGCGGAACAATATGCGCTCGATACCGGCAACGACCCGGCCGAATTTACGCA
AAAAAACATCGACAACTTCCGTCGGCAAATTAAGTCGCTTGGTTTTTCGTATGACTGGGATCGGGAAATTAACACGACTG
ATCCGAACTATTACAAATGGACGCAATGGATTTTCTTGAAGCTGTATGAAAAAGGGCTCGCCTACATGGACGAAGTACCG
GTCAACTGGTGTCCGGCGCTTGGCACCGTGCTGGCGAACGAAGAAGTCATCAATGGCCGGAGCGAGCGCGGTGGGCATCC
GGTCATCCGCAAGCCGATGCGGCAATGGATGCTGAAAATTACCGCCTATGCCGACCGGCTGCTCGAAGATTTGGAGGAGC
TTGACTGGCCGGAAAGCATTAAAGAAATGCAACGCAACTGGATCGGCCGTTCAGAAGGGGCGGAAATTGAGTTTGCTGTC
GACGGCCATGACGAGTCGTTCACAGTATTTACGACGCGGCCAGATACGCTGTTTGGCGCCACGTACGCAGTGTTGGCTCC
GGAACATCCGCTTGTTGAGAAAATTACAACGCCGGAGCAAAAACCAGCCGTTGATGCTTACTTAAAAGAAGTGCAAAGCA
AAAGCGACCTCGAGCGCACCGACTTGGCGAAAGAAAAAACAGGCGTGTTCACTGGTGCGTACGCCATCCATCCAGTTACC
GGCGACAAGCTGCCGATTTGGATCGCCGACTACGTGTTGATGGGCTACGGCACTGGGGCGATCATGGCTGTACCGGCGCA
CGATGAGCGCGACTACGAGTTTGCGAAAACATTCAACTTGCCGATCAAAGAAGTCGTTGCCGGCGGGAATGTCGAAAACG
AGCCGTACACTGGCGACGGGGAGCACATCAACTCTGAGTTTTTGAACGGCTTGAACAAACAAGAAGCGATTGAAAAAATG
ATCGCCTGGCTTGAAGAAAACGGAAAAGGACAAAAGAAAGTGTCGTACCGGCTGCGCGACTGGTTGTTCAGCCGCCAGCG
CTACTGGGGTGAGCCGATTCCGGTCATCCATTGGGAAGATGGGACGATGACGACGGTGCCGGAAGAAGAATTGCCGCTTG
TCTTGCCAAAAACGGATGAAATTAAACCGTCGGGAACGGGTGAATCGCCGCTCGCCAACATCGAAGAATGGGTCAATGTT
GTCGATCCGAAAACCGGGAAAAAAGGGCGGCGTGAAACAAACACGATGCCGCAATGGGCGGGAAGCTGCTGGTATTATTT
GCGCTACATCGACCCGCATAACGACAAACAGCTCGCCGATCCGGAAAAGTTGAAACAATGGCTGCCGGTTGACGTCTACA
TCGGCGGGGCGGAGCATGCGGTCTTGCACTTGCTGTACGCTCGCTTCTGGCATAAAGTGTTGTACGACCTTGGCATCGTG
CCGACGAAAGAGCCGTTCCAAAAGCTGTTTAACCAAGGGATGATCTTAGGCGAAAACAATGAAAAGATGAGCAAATCGAA
AGGCAATGTCGTCAACCCGGATGATATCGTCGAAAGCCATGGCGCGGATACGTTGCGGCTGTATGAAATGTTTATGGGGC
CGCTTGAAGCGTCGATCGCCTGGTCGACGAAAGGGCTTGACGGAGCGCGCCGTTTCTTAGAGCGCGTCTGGCGCCTGTTT
GTCACCGAAGATGGTCAACTGAACCCGAACATCGTTGACGAGCCAGCGAACGATACGCTCGAGCGCGTCTACCATCAAAC
GGTGAAAAAAGTGACGGAAGACTACGAAGCGCTGCGCTTCAACACTGCCATTTCGCAGCTGATGGTGTTCATTAACGAAG
CGTATAAAGCGGAGCAGATGAAAAAAGAATATATGGAAGGGTTCGTCAAGCTCTTATCGCCGGTTTGCCCGCATATTGGC
GAAGAGCTCTGGCAAAAGCTCGGCCATACTGACACCATCGCCTATGAACCATGGCCGACATATGACGAAGCGAAACTCGT
CGAAGACGTCGTTGAAATCGTCATCCAAATCAATGGCAAAGTGCGGGCGAAACTGAACGTGCCGGCGGACTTATCGAAAG
AAGCGCTAGAAGAACGGGCGCTCGCCGATGAAAAAATTAAAGAGCAGCTTGCAGGGAAAACGGTGCGTAAGGTGATCACT
GTCCCTGGTAAGCTCGTCAATATCGTCGCCAACTAA

Protein sequence :
MRRSATMSFNHREIEKKWQDYWEQHKTFRTPDESDKPKFYVLDMFPYPSGAGLHVGHPEGYTATDILARMKRMQGYNVLH
PMGWDAFGLPAEQYALDTGNDPAEFTQKNIDNFRRQIKSLGFSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYMDEVP
VNWCPALGTVLANEEVINGRSERGGHPVIRKPMRQWMLKITAYADRLLEDLEELDWPESIKEMQRNWIGRSEGAEIEFAV
DGHDESFTVFTTRPDTLFGATYAVLAPEHPLVEKITTPEQKPAVDAYLKEVQSKSDLERTDLAKEKTGVFTGAYAIHPVT
GDKLPIWIADYVLMGYGTGAIMAVPAHDERDYEFAKTFNLPIKEVVAGGNVENEPYTGDGEHINSEFLNGLNKQEAIEKM
IAWLEENGKGQKKVSYRLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLVLPKTDEIKPSGTGESPLANIEEWVNV
VDPKTGKKGRRETNTMPQWAGSCWYYLRYIDPHNDKQLADPEKLKQWLPVDVYIGGAEHAVLHLLYARFWHKVLYDLGIV
PTKEPFQKLFNQGMILGENNEKMSKSKGNVVNPDDIVESHGADTLRLYEMFMGPLEASIAWSTKGLDGARRFLERVWRLF
VTEDGQLNPNIVDEPANDTLERVYHQTVKKVTEDYEALRFNTAISQLMVFINEAYKAEQMKKEYMEGFVKLLSPVCPHIG
EELWQKLGHTDTIAYEPWPTYDEAKLVEDVVEIVIQINGKVRAKLNVPADLSKEALEERALADEKIKEQLAGKTVRKVIT
VPGKLVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68