Gene Information

Name : guaA (GTNG_0231)
Accession : YP_001124360.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 252356 - 253897 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGGATAAGATGAACCAAGAAATGATCGTCGTATTGGACTTCGGAAGCCAATATAACCAACTGATTACTCGCCGCATCCG
TGAATTTGGCGTCTACAGCGAACTGCATCCGCACACGATCAGTGCGGAAGAAATTCGCGCGTTAAATGCTAAAGGAATCA
TTTTTTCCGGTGGTCCGAACAGCGTATATGATGAACAAGCGTTTACGTGCGATCCAGCGATTTTTGAACTCGGGCTGCCA
ATCTTGGGGATTTGTTACGGGATGCAGCTTATGGCGCACCACTTGGGCGGCAAAGTGGAAAAAGCCACACACCGTGAATA
CGGCAAAGCGCTTATCCAAGTGAAAAATGATTCTTTGCTATTCCGCGGGTTGCCGGATGAACAAGTCGTCTGGATGAGCC
ACGGCGATTTAGTGACTGCCCCGCCGTCCGGTTTTATCGTCGATGCGACAAGTTCTTCCTGCCCGATCGCCGCGATGAGC
GATGAACGTCGGAAATGGTACGGGGTGCAATTCCATCCGGAAGTGCGTCATTCCATTTATGGAAATGATGTACTGAAGCG
GTTTGTTTTCGACGTATGCGGCTGTCACGGCGACTGGACGATGGAAAACTTCATCGATGAGCAAGTGCGTCGCATTCGTG
AACAAGTTGGCGGGAAAAAAGTGCTTTGTGCATTAAGCGGTGGAGTTGATTCATCGGTTGCCGCTGTATTGGTGCATCGT
GCCATCGGTGATCAGCTCACATGCATTTTTGTTGATCACGGCCTTCTTCGCAAAGGCGAAGCGGAAAGCGTCATGAAAAC
GTTCCGCGAACAGTTCCAGATGAACGTCATTAAAGTGGATGCGAAAGAACGCTTTTTGGCGAAATTAAAAGGGGTCTCCG
ACCCGGAACAAAAGCGGAAAATCATCGGCAACGAATTTATTTATGTGTTTGACGATGAGGCGGCCAAGCTCGAAGGCATT
GAATTTTTAGTGCAAGGCACGCTTTATACTGACATTATTGAAAGTGGCACAGCAACGGCACAAACGATTAAATCGCATCA
TAACGTCGGCGGCTTGCCGGAAGATATGAAATTTGAATTGATCGAGCCACTCAATACGCTGTTTAAAGATGAGGTACGCG
CACTTGGCACACAATTGGGCATTCCGGACGAAATCGTCTGGCGTCAGCCGTTCCCGGGACCTGGTCTTGGGATTCGCGTT
CTTGGTGAAGTGACGGAAGAAAAGTTGGAAATCGTCCGTGAATCGGATGCGATTTTGCGGGAAGAAGTGAAAAAAGCTGG
ACTCGACCGTGAAATTTGGCAATATTTCACCGTTCTCCCTGATATCCGCAGCGTCGGAGTGATGGGGGATGCCCGCACGT
ACGATTATACGGTCGCCATTCGCGCGGTGACATCGATCGATGGGATGACCGCCGACTGGGCTCGCATTCCTTGGGATGTG
CTCGAACGCATTTCAACACGTATCGTGAACGAAGTGCCGCACGTCAATCGCGTCGTCTACGATATTACAAGTAAACCGCC
CGCGACGATCGAGTGGGAATAA

Protein sequence :
MDKMNQEMIVVLDFGSQYNQLITRRIREFGVYSELHPHTISAEEIRALNAKGIIFSGGPNSVYDEQAFTCDPAIFELGLP
ILGICYGMQLMAHHLGGKVEKATHREYGKALIQVKNDSLLFRGLPDEQVVWMSHGDLVTAPPSGFIVDATSSSCPIAAMS
DERRKWYGVQFHPEVRHSIYGNDVLKRFVFDVCGCHGDWTMENFIDEQVRRIREQVGGKKVLCALSGGVDSSVAAVLVHR
AIGDQLTCIFVDHGLLRKGEAESVMKTFREQFQMNVIKVDAKERFLAKLKGVSDPEQKRKIIGNEFIYVFDDEAAKLEGI
EFLVQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMKFELIEPLNTLFKDEVRALGTQLGIPDEIVWRQPFPGPGLGIRV
LGEVTEEKLEIVRESDAILREEVKKAGLDREIWQYFTVLPDIRSVGVMGDARTYDYTVAIRAVTSIDGMTADWARIPWDV
LERISTRIVNEVPHVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 74
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 74
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 74
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-138 54