Gene Information

Name : pykA (GTNG_2663)
Accession : YP_001126753.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 2771815 - 2773578 bp
Length : 1764 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGAAGCGGAAAACGAAAATCGTCTGTACCATTGGGCCGGCAAGTGAAAGTGTGGACAAGCTTGAACAACTGATTGAAGC
GGGAATGAACGTAGCACGCCTGAATTTTTCGCATGGCGATCACGAGGAACATGGACGGCGCATTGCCAACATTCGTGAGG
CAGCGCAGCGAACGGGCAAAACGGTCGCCATTTTGCTTGATACGAAAGGCCCGGAAATCCGGACGCACAATATGGAAAAC
GGCGCGATCGAACTGAGAGAAGGAGCGAAGCTGGTCATTTCGATGAGCGAAGTGCTCGGCACGCCAGAAAAGATCTCGGT
CACTTATCCGGGATTGATCGATGACGTATCTGTTGGTTCGAAAATTTTGCTCGACGATGGGTTGATCGCCCTTGAGGTCA
ATGCAGTTGACAAGCAAGCCGGAGAAATTATCACGACCGTTTTAAACGGCGGCGTGTTGAAAAACAAAAAAGGGGTCAAC
GTCCCGGGGGTGCGCGTCAACTTGCCGGGGATTACCGAGAAAGACCGGGCCGATATTTTGTTTGGCATTCGTCAAGGAAT
CGACTTTATCGCTGCCTCGTTCGTTCGTCGAGCGTCCGATGTGCTCGAAATTCGCGAGCTGCTTGAAGCGAACGATGCCC
TCCATATCCAAATTATCGCCAAAATTGAGAATGAAGAAGGCGTCGACAACATCGACGAAATTTTAGAAGCAGCCGACGGC
CTCATGGTGGCCCGCGGTGATTTAGGCGTCGAAATTCCGGCTGAGGAAGTGCCGCTCATCCAAAAGTTGTTGATCAAAAA
GTGCAATATGCTCGGTAAGCCGGTCATTACAGCGACGCAAATGCTTGATTCGATGCAGCGCAACCCGCGGCCGACGCGGG
CGGAAGCAAGCGACGTCGCCAACGCCATTTTTGACGGCACAGATGCTGTCATGCTTTCTGGGGAAACGGCGGCTGGTCAA
TATCCAGTTGAAGCGGTCAGAACGATGCACCAAATTGCACTCCGCACCGAACAGGCGCTTGAGCACCACGATATTTTGTC
CCAGCGCACAAAAGAAAGCGCGACGACGATTACCGATGCCATCGGACAGTCAGTCGCTCATACAGCCTTAAATTTAGATG
TAGCAGCGATCGTCACGCCGACGGTGAGCGGGAAAACGCCGCAAATGGTGGCGAAATACCGCCCGAAAGCACCGATTATT
GCTGTCACCTCAAACGAAGCGGTATCGCGCCGGTTGGCGCTCGTATGGGGCGTCTATACGAAAGAAGCGCGGCATGTGAA
CACGACGGATGAAATGCTCGATGTCGCCGTCGATGCCGCGGTGCGTTCCGGTTTGGTGAAGCACGGTGATTTAGTCGTCA
TCACCGCCGGGGTTCCGGTCGGTGAGACCGGTTCGACGAACTTAATGAAAGTGCACGTCATCAGCGACTTGATCGCGAAA
GGACAAGGCATCGGCCGCAAGTCGGCGTTTGGCAAGGCCGTTGTGGCGAAAACAGCGGAAGAAGCGTGTCAAAAAATGGT
CGAGGGTGGCATTTTAGTCACCATCAACACCGATGCCGATATGATGCCGGCAATTGAAAAGGCGTCGGCGATCATTACCG
AGGAAGGCGGATTGACAAGCCATGCCGCGGTTGTTGGCCTAAGCCTTGGCATTCCTGTCGTTGTCGGGGTGAACAATGCA
ACAAGCTTGTTTAAAGACGGGCAAGAAATTACGGTCGACGGAGGGTTTGGTGCTGTCTACCGCGGCCACGCAAGCGTCTT
GTAA

Protein sequence :
MKRKTKIVCTIGPASESVDKLEQLIEAGMNVARLNFSHGDHEEHGRRIANIREAAQRTGKTVAILLDTKGPEIRTHNMEN
GAIELREGAKLVISMSEVLGTPEKISVTYPGLIDDVSVGSKILLDDGLIALEVNAVDKQAGEIITTVLNGGVLKNKKGVN
VPGVRVNLPGITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEANDALHIQIIAKIENEEGVDNIDEILEAADG
LMVARGDLGVEIPAEEVPLIQKLLIKKCNMLGKPVITATQMLDSMQRNPRPTRAEASDVANAIFDGTDAVMLSGETAAGQ
YPVEAVRTMHQIALRTEQALEHHDILSQRTKESATTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPII
AVTSNEAVSRRLALVWGVYTKEARHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVGETGSTNLMKVHVISDLIAK
GQGIGRKSAFGKAVVAKTAEEACQKMVEGGILVTINTDADMMPAIEKASAIITEEGGLTSHAAVVGLSLGIPVVVGVNNA
TSLFKDGQEITVDGGFGAVYRGHASVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-111 53
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 6e-112 53
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 6e-112 53
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-111 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykA YP_001126753.1 pyruvate kinase VFG0479 Protein 3e-112 53