Gene Information

Name : hemC (GTNG_2574)
Accession : YP_001126664.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : -
Position : 2679336 - 2680265 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGCGAAACATCGTCGTTGGCTCGCGGCGCAGCAAGCTTGCTTTGACTCAGACGAACTGGGTCATTAACGAATTGAAGCG
GCTCGGGGCGCCGTTTACGTTTGAGGTAAAAGAAATCGTCACGAAAGGAGATCGCGTGCTCGATGTCACGCTCTCCAAAG
TAGGAGGCAAAGGGCTGTTTGTGAAAGAAATTGAGCATGAAATGCTGACCGGCGGCATCGATATGGCCGTCCACAGTATG
AAAGACATGCCGGCAGTACTGCCGAGCGGATTGGTGATCGGCTCGGTTCCGCGGCGTGAGGATGTGCGTGATGTGCTCGT
CAGCAAGGGGAATCTGTCGCTTTCCGATTTGCCAAGCGGGGCGGTCATCGGTACGAGCAGTCTGCGCCGCTCGGCACAGT
TGCTCGCCTATCGGCCGGATGTGACGATCAAATGGATCCGCGGCAACATTGACACAAGGCTGGCGAAGCTGAAAAACGAA
GATTATGACGCCATCGTGCTGGCGGCTGCCGGCTTGGCGCGTATGGGCTGGAGCGATGACGTGATCAGCGAATATTTGTC
GCCGGATGTGTGCGTCCCGGCGGTTGGCCAAGGAGCGCTTGCTGTCGAATGCCGTGAAGATGATGTGGAGTTGCGCGAGT
GGCTGAGCCGTCTGAATGATGAACAGACGGAACGAGCAGTTCGGGCGGAGCGCGCCTTTTTGCAGCAGATGGAAGGTGGA
TGCCAAGTGCCGATTGCCGGCTATGCGGAAGTGAAGGAGGGAATGGTGCATCTTACTGCGCTTGTTGCCTCCCCAGACGG
CAAAGAGAAATACAAAGAAATCGTCATTGGCGCTGATCCGGAAGAGGTCGGCCGACAGGCAGCTGCCCTCCTGAGTGAGC
AAGGGGCCAAAGAGCTGATCGAGCGCGTAAAAAAGGAGCTGGGCAACTAA

Protein sequence :
MRNIVVGSRRSKLALTQTNWVINELKRLGAPFTFEVKEIVTKGDRVLDVTLSKVGGKGLFVKEIEHEMLTGGIDMAVHSM
KDMPAVLPSGLVIGSVPRREDVRDVLVSKGNLSLSDLPSGAVIGTSSLRRSAQLLAYRPDVTIKWIRGNIDTRLAKLKNE
DYDAIVLAAAGLARMGWSDDVISEYLSPDVCVPAVGQGALAVECREDDVELREWLSRLNDEQTERAVRAERAFLQQMEGG
CQVPIAGYAEVKEGMVHLTALVASPDGKEKYKEIVIGADPEEVGRQAAALLSEQGAKELIERVKKELGN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-57 47
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-57 47