Gene Information

Name : GTNG_2473 (GTNG_2473)
Accession : YP_001126563.1
Strain : Geobacillus thermodenitrificans NG80-2
Genome accession: NC_009328
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : -
Position : 2577260 - 2578393 bp
Length : 1134 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAGACGAAAAACGTTGCTCATTCATGGCGGCATTCCGGGTGACCCGCATACAGGGGCGGTGTCGGTGCCGATTTATCA
AGTGAGTACGTACAAGCAAGAAGAAGTTGGAAAGCATAAAGGATTTGAATACTCGCGTACCGGCAACCCGACGCGTGCAG
CGCTCGAAAAACTGATTGCTGACCTCGAAGGCGGCGAGGCCGGGTTCGCGTTCGCTTCCGGAATGGCGGCGATTACGGCC
GTCATGATGCTGTTTGACAGCGGGGATCATATTGTGCTCACCGATGACGTTTACGGCGGCACGTATCGAGTGATGGCGAA
CGTGTTAAACCGATTCGGATTGGAATCGACGTTCGTCGATACGAGCGACATCGCCAACATAGAGGCGCACATTCGTCCAA
ATACGAAAGCCATTTACATTGAGACACCGACGAATCCGTTGTTGAAAATCACGGATTTGAAGGCCGCCGCCGCCATTGCC
CGTGCGCACGGGCTGCTATTGATCGTCGATAACACGTTTTCGACACCGTACTTTCAAACGCCGCTTGAGCTTGGCGCTGA
TATCGTCATCCATAGCGCGACGAAATATTTAGGCGGTCATAGTGACGTCGTCGCCGGACTGGCTGTTGTCCGCACCGCCG
AGCTCGCCGAGCGGCTTCATTACGTGCAAAATTCGACGGGCGGCATCCTTGGACCGCAAGATTCGTGGCTGCTTATGCGC
GGGATGAAAACGCTTGGCGTGCGGATGGAAGAGCATGAACAAAATGCGCGGGCAATTGCCGCCTTTTTGGCGGAGCATCA
GGCGGTTACCCGCGTGTATTATCCTGGGCTTCCGGAGCATCCGAACCATGAGCTGGCGAAAGCACAAATGCGTGGGTTCG
GCGGCATGATTTCGTTCGATGTCGGCAGCCTTGAGCGCGCTGAAACGGTGCTGTCGCGTGTCCGCTACTTTACGCTAGCT
GAAAGTTTAGGGGCAGTCGAAAGCTTAATTTCATTGCCAGGGAAAATGACACATGCGTCGATCCCGAAAGAGCGGCGTGA
ACAGCTCGGCATTACTGATGGGCTCATCCGTCTATCGGTCGGCCTTGAAGACGTCAATGATTTGATTGACGATTTGGCGC
AAGCGCTTGGTTGA

Protein sequence :
MRRKTLLIHGGIPGDPHTGAVSVPIYQVSTYKQEEVGKHKGFEYSRTGNPTRAALEKLIADLEGGEAGFAFASGMAAITA
VMMLFDSGDHIVLTDDVYGGTYRVMANVLNRFGLESTFVDTSDIANIEAHIRPNTKAIYIETPTNPLLKITDLKAAAAIA
RAHGLLLIVDNTFSTPYFQTPLELGADIVIHSATKYLGGHSDVVAGLAVVRTAELAERLHYVQNSTGGILGPQDSWLLMR
GMKTLGVRMEEHEQNARAIAAFLAEHQAVTRVYYPGLPEHPNHELAKAQMRGFGGMISFDVGSLERAETVLSRVRYFTLA
ESLGAVESLISLPGKMTHASIPKERREQLGITDGLIRLSVGLEDVNDLIDDLAQALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-92 59
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 3e-93 59
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-67 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
GTNG_2473 YP_001126563.1 cystathionine beta-lyase BAC0207 Protein 4e-59 45