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Name : thyA (FTW_0717) Accession : YP_001121720.1 Strain : Francisella tularensis WY96-3418 Genome accession: NC_009257 Putative virulence/resistance : Unknown Product : thymidylate synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0207 EC number : 2.1.1.45 Position : 697277 - 698101 bp Length : 825 bp Strand : - Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived DNA sequence : ATGCGAGAATATCTAAATTTCCTTAAGTATATCAAAGAAAATGGCGTTTTAAAGGGTGATAGAACCGGTACTGGAACAAG AAGTATCTTTGGCTATCAAATGCGTTTTGATCTTCAAAAAGGCTTCCCATTAGTAACTACAAAAAAAATTCATATTCCTA GTGTTGTTCATGAATTATTATGGTTTTTAAGTGGTAGTACAAATATCAAATATCTTAATGATAACAATGTTAGAATTTGG AATGAGTGGGCAACTGTAGATGGCGAACTTGGTCCTATTTATGGCAAGCAGTGGCGTGATTTTAATGGTCAAGGTATAGA TCAAATTGCCGATGTAATTCAGATGCTAAAAACAAACCCAAACTCACGTAGGATTCTAGTTTCAGCGTGGAATCCATGTG TTGTTCCATCAGAAAAAATCTCTCCACAAGAAAATGTTGTAAAAGGTAATTCAGCCCTACCACCATGCCATGCAATGTTT CAGTTCTATGTAGCAAATAATAAACTATCATGCATGCTTACGCAAAGAAGTGCTGATGCTTTTCTTGGAGTGCCATTTAA CATTGCAAGTTATTCACTACTGACACATATGGTTGCACAACAATGTAATCTTGATGTTGGTGAGTTCATCTGGTCAGGTG GTGATTGTCATATTTACAATAATCATATTGAGCAAGTCAATGAACAGCTTAGTCGTGAGCCTTTAGCTTTACCAACACTA AAGATTTTAAGAAAACCAAACTCCATCTTTGATTATAAATACGAAGATTTTGAATTTGAGAACTATAACCATCACCCTGC CATCAAAGCAAAAATATCTGTATAA Protein sequence : MREYLNFLKYIKENGVLKGDRTGTGTRSIFGYQMRFDLQKGFPLVTTKKIHIPSVVHELLWFLSGSTNIKYLNDNNVRIW NEWATVDGELGPIYGKQWRDFNGQGIDQIADVIQMLKTNPNSRRILVSAWNPCVVPSEKISPQENVVKGNSALPPCHAMF QFYVANNKLSCMLTQRSADAFLGVPFNIASYSLLTHMVAQQCNLDVGEFIWSGGDCHIYNNHIEQVNEQLSREPLALPTL KILRKPNSIFDYKYEDFEFENYNHHPAIKAKISV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| thyA | YP_001800914.1 | thymidylate synthase | Not tested | Not named | Protein | 2e-74 | 59 |
| thyA | YP_189147.1 | thymidylate synthase | Not tested | ¥ÕSP¥â | Protein | 4e-48 | 45 |
