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Name : tktA (FTW_0522) Accession : YP_001121557.1 Strain : Francisella tularensis WY96-3418 Genome accession: NC_009257 Putative virulence/resistance : Unknown Product : transketolase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0021 EC number : 2.2.1.1 Position : 508178 - 510169 bp Length : 1992 bp Strand : + Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo DNA sequence : ATGTCTTTATCTATTCCACGCGAGTTTTCAAACGCTATAAGATTTTTATCTATTGATGCAACACTTAAAGCTAAATCAGG ACATCCTGGAATGCCTATGGGGATGGCTGATATTGCCACAGTGTTATGGACAAAGTTTCTTAAGCACAATCCAAATAATC CACATTGGATAAATAGAGATAGATTTGTTCTTTCAAATGGGCATGGCTCAATGCTTTTATATTCTCTGTTACATCTGACA GGTTATGATCTATCTATTGAGGATATTAAAAATTTTAGGCAGTTACACTCAAAAACTCCAGGGCACCCTGAGTATGGCTA TACGCCAGGAGTTGAGACAACAACTGGTCCATTAGGGCAAGGAGTAGCAAATGCTGTGGGTATGGCTTTAGGTGAAAAGC TATTATCAGATAGGTATAATACACCTGATTTAAAAGTTATAGATCATCACACTTACGTGTTTTTAGGTGATGGATGTTTG ATGGAGGGTGTTTCTCATGAAGCATGCTCATTAGCAGGGACTCTAGGTTTAAACAAATTAGTAGCATTTTGGGATGATAA TAATATTTCGATAGATGGCGATACTAAGGGTTGGTTTAGTGATAATACACCTGAGAGATTTAGGGCGTATGGTTGGCATG TTATAGAAAATGTTGATGGTCATGATTTTGTTGCGATTGAAAAAGCTATAAATGAAGCCCATTCTCAGCAGCAAAAACCA ACTTTAATCTGTTGTAAAACTGTAATTGGTTTTGGCTCACCTGAGAAAGCTGGAACTGCCTCTGTGCATGGTTCGCCTTT AAGTGATCAAGAAAGAGCCTCAGCTGCTAAAGAGCTTAACTGGGATTATCAAGCTTTTGAAATACCTCAAGATGTTTATA AATACTGGGATGCTAGGGAAAAAGGACAAGCTTTAGAAGCAAATTGGCAAGGGCAATGGAATTTATTTAAAGACAGTCCT AAGTTTGACGAATTTGAACGAGTTTTAAGTAAAGAGTTGCCAGTTGGATTAGAAAGCGCTATTAATGACTATATAGCTTC GCAATTGAGTAATCCTGTCAAAGTGGCAACACGTAAAGCTTCACAAATGGTGCTTGAAGTCTTGTGTAAGAATATGCCTG AGATGTTTGGTGGATCAGCAGATTTGACAGGATCAAATAATACTAATTGGAGTGGTTCAGTTTGGCTAAATAATACTCAA GAAGGCGCAAATTATCTTTCTTATGGTGTTAGAGAGTTTGGTATGGCTGCAATAATGAATGGTCTAAGCCTTTATGGTGG TATCAAACCTTATGGTGGTACATTCTTGGTATTTAGCGATTATTCAAGAAACGCGATAAGAATGTCAGCGTTGATGAAAC AGCCTGTAGTTCATGTTATGTCGCATGACTCAATTGGTTTGGGAGAAGATGGATCAACTCATCAACCTATAGAACATGTT CCGAGTTTAAGACTTATACCTAACTTAAGTGTTTGGCGACCTGCTGATACAATTGAAACAATGATAGCATGGAAAGAGGC TGTAAAATCTAAAGATACGCCAAGTGTAATGGTACTTACACGTCAAAACTTAATGCCAGTAGTGCAAACACAGCATCAGG TAGCAAATATTGCTAGAGGTGGTTATCTAGTTAAAGATAATCCTGATGCTAAATTAACTATTGTTGCTACTGGCTCTGAA GTTGAGCTTGCTGTCAAAGTTGCTAATGAATTTGAAAAGAAAGGTATAAAATTAAATGTTGCTTCTATACCGTGTGTAGA AGTTTTTGCTACTCAAGCTCACGAGTATAAAAAAACAGTAATAAAAGATGATATCCCGGCAGTTTTTGTTGAGATGGCGC AACCTGATATGTGGTATAAATATATGCCAAAAGCTGGAGGGGAAGTAAAAGGAATCTATAGCTTTGGTGAGTCAGCACCG GCTGAAGATTTATTTAAACGTTTTGGATTTACTGTAGAAAATATTAGCAATATTGTTGCTAAATATGTTTAA Protein sequence : MSLSIPREFSNAIRFLSIDATLKAKSGHPGMPMGMADIATVLWTKFLKHNPNNPHWINRDRFVLSNGHGSMLLYSLLHLT GYDLSIEDIKNFRQLHSKTPGHPEYGYTPGVETTTGPLGQGVANAVGMALGEKLLSDRYNTPDLKVIDHHTYVFLGDGCL MEGVSHEACSLAGTLGLNKLVAFWDDNNISIDGDTKGWFSDNTPERFRAYGWHVIENVDGHDFVAIEKAINEAHSQQQKP TLICCKTVIGFGSPEKAGTASVHGSPLSDQERASAAKELNWDYQAFEIPQDVYKYWDAREKGQALEANWQGQWNLFKDSP KFDEFERVLSKELPVGLESAINDYIASQLSNPVKVATRKASQMVLEVLCKNMPEMFGGSADLTGSNNTNWSGSVWLNNTQ EGANYLSYGVREFGMAAIMNGLSLYGGIKPYGGTFLVFSDYSRNAIRMSALMKQPVVHVMSHDSIGLGEDGSTHQPIEHV PSLRLIPNLSVWRPADTIETMIAWKEAVKSKDTPSVMVLTRQNLMPVVQTQHQVANIARGGYLVKDNPDAKLTIVATGSE VELAVKVANEFEKKGIKLNVASIPCVEVFATQAHEYKKTVIKDDIPAVFVEMAQPDMWYKYMPKAGGEVKGIYSFGESAP AEDLFKRFGFTVENISNIVAKYV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| tktA | AAO17218.1 | TktA | Not tested | tcd island | Protein | 0.0 | 56 |
| APECO1_2641 | YP_859417.1 | transketolase | Not tested | Not named | Protein | 2e-179 | 55 |
