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Name : wbtA (FTW_0411) Accession : YP_001121460.1 Strain : Francisella tularensis WY96-3418 Genome accession: NC_009257 Putative virulence/resistance : Virulence Product : NAD dependent epimerase/dehydratase family protein Function : - COG functional category : M : Cell wall/membrane/envelope biogenesis COG ID : COG1086 EC number : - Position : 408344 - 409942 bp Length : 1599 bp Strand : + Note : component of putative O antigen gene cluster DNA sequence : TTGTCATCTTTTTTACTACTTAGAGATTATATGGCTAGTTGGCGTAAGTCGACTCAAAAAACTTTTTTACGTAAGGCTTT TATTAATTTGCCAGTATTTTTCATAGTGGCATTATTTTTTTATGGCAAAGTCACTTTTTCGTTGATATTCTCTGAGTTTT TATTTTATGTTTTTTTGATCAGTTTAAGTGTCTACTTTTATTGGTATTTGATGAACAGAGGATCAGTGGATAAAAGTAAA ACTGCGGTTATTTATGGTGCAGGTGCTGCAGGAACAAAGATTGCTCAAGAACTTGCTTCTGCTGGTTATCGCATCAAATG TTTTGTTGATGACAATGAAACTTTACAAAAAAGAAGTATTGATAGTAAAAAGGTTCTATCTAAAGCTGAATTAACAAAAC TATTGCTATCTAGTAGATTTGACCTTTTGGTTATTGCATTGCCAAGAAATGCAAACCAAGTAGTCAAAAATATATATAAA GAATTTGAAAAGGATTTTAATCAGATTAGAATTATGCCGCCTCTTGAGGAAATTCTTCAAGATGAGAATTTTATGTCACA GTTGAAGCCTGTTTCACTCTATGATCTATTAGCGCGTGATACTAAGAGTTTAGATAAAGAATCTATCTCTAATTTTATCA AAAATAAGGTGGTGCTAGTCACAGGAGCTGGAGGTAGTATAGGTTCTGAAATAGTACATCAATGTATCAAGTATCAGGCA AAAGAGTTGATATTGGTTGATCATAGTGAGTTTAACTTATATAAAATTACTGAGGAGTGTAGTCATTTTAATATCAATAG TGTGCTATGTTCTGTTTGTGATAGAAAAGCATTGGCTGAGGTTTTTCAAAAGTATACTCCAAATATAGTATTTCATGCTG CTGCCTACAAGCATGTTCCCTTAGTTGAGGAGAATATCTCTAGAGCAATTAGAAATAATATCTTAGGTACTAAGAATGCT ATAGATCTGGCTATAGAAGCTGGTGTTGAGTCATTTATATTGATTTCCACTGATAAAGCAGTGCGACCAACGAATGTTAT GGGGGCTACCAAGAGAGTTTGTGAGCTGTATTTACAGAATGTTGATCCCAAAAATACCAAGCTTGCTGCAGTGCGTTTTG GTAATGTGCTTGGTAGTAGTGGCAGTGTGATTCCAAAATTTGAAGAGCAAATAAGAAATGGTGGTCCTGTTACAGTTACT CATCCTGAAATTACACGTTATTTTATGTTGATACCAGAAGCTTGTGAACTGGTCCTACAAGCTGGTGCTATTGCAAAAAA TTCAGAGGTCTTTGTCTTAGATATGGGGCAACCTGTCAAGATTATTGATCTTGCTAAACAATTTATTAGACTTTCTGGTA GAGGTGATATTGATATTAAAATAGTTGGTTTGCGTCCAGGAGAGAAACTTTACGAAGAGCTTTTGATAGAGGAAGATGAT GTTAGTACCGACTATAAAGATATTTTTATTGGTAGAAGGACTTTTTACGATATTAATACTCTAAACCAAGATATTGAATC GTTGATCAAGGATGATGTTGATCAGCTTGTGATATTAAAGAAAATTGTTCCGGAATTTGAACATAGATTGAATGGGTAG Protein sequence : MSSFLLLRDYMASWRKSTQKTFLRKAFINLPVFFIVALFFYGKVTFSLIFSEFLFYVFLISLSVYFYWYLMNRGSVDKSK TAVIYGAGAAGTKIAQELASAGYRIKCFVDDNETLQKRSIDSKKVLSKAELTKLLLSSRFDLLVIALPRNANQVVKNIYK EFEKDFNQIRIMPPLEEILQDENFMSQLKPVSLYDLLARDTKSLDKESISNFIKNKVVLVTGAGGSIGSEIVHQCIKYQA KELILVDHSEFNLYKITEECSHFNINSVLCSVCDRKALAEVFQKYTPNIVFHAAAYKHVPLVEENISRAIRNNILGTKNA IDLAIEAGVESFILISTDKAVRPTNVMGATKRVCELYLQNVDPKNTKLAAVRFGNVLGSSGSVIPKFEEQIRNGGPVTVT HPEITRYFMLIPEACELVLQAGAIAKNSEVFVLDMGQPVKIIDLAKQFIRLSGRGDIDIKIVGLRPGEKLYEELLIEEDD VSTDYKDIFIGRRTFYDINTLNQDIESLIKDDVDQLVILKKIVPEFEHRLNG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| cap1D | AAA64643.1 | type 1 capsule synthesis gene | Virulence | SCCcap1 | Protein | 2e-75 | 44 |
| SSP0063 | YP_300153.1 | capsular polysaccharide biosynthesis protein | Not tested | SCC15305cap | Protein | 7e-71 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| wbtA | YP_001121460.1 | NAD dependent epimerase/dehydratase family protein | VFG1300 | Protein | 2e-74 | 42 |
