Gene Information

Name : smpB (FTW_1234)
Accession : YP_001122136.1
Strain : Francisella tularensis WY96-3418
Genome accession: NC_009257
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1162951 - 1163424 bp
Length : 474 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAGTAAACATAAGGTTTCTCCAGCGACTATTGCTAAAAATAAAAAAGCCTTGCATGATTATACTATTTTAGAGAAATT
TGAAGCCGGAATAGTTCTACAAGGTTGGGAAGTAAAAAGTATTCGCGCTGGTAAAGTACAAATGGTTGATAGTCATGTGC
ATATTAAACATGGTGAAGCGTGGCTTTTTAATTGTCTAATCACACCTTTGCTATCTGCCTCAACTCATGTGGTTGCAGAT
GCTGCAGCAACACGCAAGCTACTTCTCAATCGTCGTGAGATTAATAAGATTATGGGTAGAATTGAGCAAAAAGGTTTTAC
ATGTATACCTCTTTCTATGTATTGGAAAGGTCCACGAGTAAAAGTAGAAATAGCATTAGCTCAAGGTAAAAAAGTTCATG
ATAAGCGCCAAGCACAAAAAGACAAAGACTGGGCACGCGAAAAAGATAGATTATTTAAAAAGGCTTATAAATAA

Protein sequence :
MSKHKVSPATIAKNKKALHDYTILEKFEAGIVLQGWEVKSIRAGKVQMVDSHVHIKHGEAWLFNCLITPLLSASTHVVAD
AAATRKLLLNRREINKIMGRIEQKGFTCIPLSMYWKGPRVKVEIALAQGKKVHDKRQAQKDKDWAREKDRLFKKAYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 2e-34 52
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 2e-20 44
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-19 44