Gene Information

Name : Dred_0381 (Dred_0381)
Accession : YP_001111754.1
Strain : Desulfotomaculum reducens MI-1
Genome accession: NC_009253
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : -
Position : 407452 - 409188 bp
Length : 1737 bp
Strand : +
Note : PFAM: pyruvate kinase; PEP-utilising enzyme, mobile region; KEGG: chy:CHY_1144 pyruvate kinase

DNA sequence :
ATGCGTAAAACAAAAATAGTTTGTACCATAGGACCAGCCAGCGAAAGATTAGAAACCATTAATGAAATGATCAAAGCTGG
TATGAATGTTGCCAGACTGAACTTTTCGCACGGTTCCCATGAGGAACATGCTAAGCGTATCACAACCATTCGTTGTGCAG
CACAAGAGATGGGACAAAATATTGCTATTTTATTAGATACCAAAGGTCCTGAAATCAGGCTGGGGGATTTTCAGGAACAA
CCAGTGCTACTAGAGGCAGGACAGTCATTTTTTTTAACAACCGAACCGATTATAGGGGATCAGCACGGAGTTTCCGTTAC
ATATGAGGACCTGTCAAAGGATGTCAAAAGGGGAGACCGTATCCTGGTTGACGATGGTCTAATTGAATTAGTAGTTGAAG
CTGTTGAAGAAAAAAAGATAGTTTGCCGGGTAATGAATGGCGGAAAAGTTTCTAACCGCAAAGGAGTAAATTTACCGGAT
ATTCATGTAAACTTACCGGCGGTAACGGAGAAGGATATTGCAGATATCAAATTTGGCATAGAACAGCAAGTGGATTTTAT
TGCGGCATCCTTTGTACGCAAGGCTGGGGATGTCTTAGCCATTCGGAAAATTTTGGAGGATGACGGGGCTAAAATTGATA
TTATTGCCAAGATAGAAAGCCGAGAAGCAGTTGATAATCTGGATGAGATTATCCAAGCATCAGATGGTATCATGGTGGCC
CGGGGTGACCTAGGGGTAGAAATTCCGGCTGAAGAAGTACCCATTATTCAAAAAAAAATAATAACCATTTGTAACCAAGT
AGGAAAGCCCGTGATTACCGCTACCCAAATGCTTGATTCCATGATTCAAAACCCTCGCCCGACCAGGGCAGAGGCCAGTG
ATGTGGCGAATGCCATCTTTGATGGAACTGACGCCATCATGCTATCCGGGGAATCTGCCAATGGCAAATATCCCGTTGAA
GCTGTAAGGACAATGGATCGCATTGCCAGACGTTCGGAACAAGCCCTGAGCGACGGGGCTAAAACATACACTAACTGCTT
TAGTGTTACCGATGCCCTAGGTCAGGCCGTATGTACTGTGGCCAACCAACTGGACGCAGCTGCCATTATTACTGCCACCA
CCAGTGGCTATACGGCAAAGATGATTTCACGCTATCGCCCCCAATCAGCCATTGTGGCGGTGACGCCGGACCGAGGTGTC
ATGAGACGGCTGTCATTGGTTTGGGGAGTGGTTGCATTACCTTCACCAAAGCTTACCAACACAGACCAAATGATTGCTAC
AGCGGTGGATACCGCAGTGGAACAAAAAGTCGTAAAGGGTGGAGATCTAGTAGTCATCACTGCAGGGGTACCTGTAGGAC
TTCAGGGAACCACCAACTTGATGAAGATTCATACTGTAGGAACCATAGTGTCCAGTGGTACAGGGATTGTTGCACAGGCT
GTGTCTGGGCCGGTAAGGGTATGCAATGATGCTGAAGAGGCGGCTAGGCTGGAACCAGGTGAAATCCTCGTAACCAACGG
AACTGATGCAGGCTTTGTACCATTCCTGAAGAATGCTGCTGCCATTGTGGCGGAAGAGGGAGGGCTAACCTCTCACGCAG
CAATTTTAGGACTGGAGCTAAAGGTTCCAACCATTGTGGGAGCGAAAGGTGCCAGCGGAATATTTAAAAATGGTGAAATC
ATTACAGTGGATGGTCAAAGTGGTGTTATTTACAGAGGAAACGCCAAGGTTTTCTAA

Protein sequence :
MRKTKIVCTIGPASERLETINEMIKAGMNVARLNFSHGSHEEHAKRITTIRCAAQEMGQNIAILLDTKGPEIRLGDFQEQ
PVLLEAGQSFFLTTEPIIGDQHGVSVTYEDLSKDVKRGDRILVDDGLIELVVEAVEEKKIVCRVMNGGKVSNRKGVNLPD
IHVNLPAVTEKDIADIKFGIEQQVDFIAASFVRKAGDVLAIRKILEDDGAKIDIIAKIESREAVDNLDEIIQASDGIMVA
RGDLGVEIPAEEVPIIQKKIITICNQVGKPVITATQMLDSMIQNPRPTRAEASDVANAIFDGTDAIMLSGESANGKYPVE
AVRTMDRIARRSEQALSDGAKTYTNCFSVTDALGQAVCTVANQLDAAAIITATTSGYTAKMISRYRPQSAIVAVTPDRGV
MRRLSLVWGVVALPSPKLTNTDQMIATAVDTAVEQKVVKGGDLVVITAGVPVGLQGTTNLMKIHTVGTIVSSGTGIVAQA
VSGPVRVCNDAEEAARLEPGEILVTNGTDAGFVPFLKNAAAIVAEEGGLTSHAAILGLELKVPTIVGAKGASGIFKNGEI
ITVDGQSGVIYRGNAKVF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 7e-93 49
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-93 49
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-93 49
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-92 49

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Dred_0381 YP_001111754.1 pyruvate kinase VFG0479 Protein 1e-93 49