Gene Information

Name : leuS (Dred_2515)
Accession : YP_001113850.1
Strain : Desulfotomaculum reducens MI-1
Genome accession: NC_009253
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2734802 - 2737285 bp
Length : 2484 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
TTGCAAGAGCACTACGACTTCAAGGAAATAGAGAAAAAATGGCAAGAGGACTGGAATAAGGAAAATACCTATCAAGTTCC
GGATTTTTCAGAGCGTCCTAAATATTACTGCTTGGAAATGTTTCCTTACCCCTCCGGTAAACTGCACATGGGTCATGTAA
GGAACTATTCCATTGGTGATGTAGTGGCCAGATTTAAAACCATGCAGGGTTACGATGTACTACATCCAATGGGTTGGGAT
GCTTTTGGCTTACCTGCAGAAAATGCTGCTATTAAACATGGTATTGCCCCGGCCACTTGGACTTGGGATAACATTGCACA
TATGAGAAGCCAGTTAAAACAACTTGGCTTAAGTTATGATTGGAACCGGGAAGTAGCTACCTGTCATACTGAATATTACA
AATGGGGACAATGGTTGTTCCTTCAACTCTATAAAAAGGGCCTATGCTATAAAAAACACGCTCGGGTTAATTGGTGTCCG
GATTGTGCCACCGTTCTGGCCAACGAACAGGTGGTTGACGGTGCTTGTGAAAGATGCAGTGCCGTGGTTGAACAAAAGGA
GTTAGACCAATGGTTTTTCCGAATTACAGAATACGCCCAGCGTTTGCTTAATGACTTAAAATTGTTAAAGGGTTGGCCCG
ATAAAGTTAAGATTATGCAAGAAAACTGGATAGGTCGTAGTGAAGGTGCTGAGCTAACCTTTCAAGTAGAGGGAAGTGAT
GAAAGCATTACCGTCTTTACCACCCGTCCGGATACGGTCTACGGTGTATCCTATATGGTTTTGGCGCCGGAACATCCACT
GGTAGCCAAGCTGATTGCTGGTAGACCTCAGGAGGCAGAGGTCATTGGCTTTGTTAACCGAGTAAACAAATTAACTGAAT
TAGACCGTACCAGTTCTGATAAAGAGGGCGTTTTTACTGGGGCCTACTGTATTAACCCCTTTGACGGTGCGAGAGTACCC
ATTTTGATAGCCAATTATGTTCTATACCACTATGGTACTGGTGCTGTGATGGGCGTGCCTGCCCACGATGAGCGTGATTT
CGAATTTGCTCATAAATACAATTTACCAATAAAAGTTGTTATTTATCCTGCCCAGGATAAGGAAATTAGGGTTGAGGATA
TGAAGGAAGCCTATACCGCAGACGGAATTATGGTTCATTCCGGTCCCTTTGATGGAAGTCCCAACCGTCAAGGTATAAAA
AAGGTGATTAAATACGCCGAGGAAAAGGGGATCGGTAAAGGAATTGTCAACTATCGATTAAGGGATTGGCTAATTTCCCG
CCAGCGTTATTGGGGTACCCCTATCCCCATTGTTTATTGTGAAAAATGTGGAACTGTACCGGTACCAGAGGATCAACTGC
CGGTAATATTGCCCACCGATGTGGCCTTTAAGCCAACCGGTGAGTCACCCCTAAAGGGTAGGCCAGACTTTGTTCATACC
ACTTGCCCTCAATGTGGTGGACCTGCCCAAAGAGAAACTGACACAATGGATACCTTTGTGGACTCTTCTTGGTATTATCT
GCGCTATACCAGTTCCAGAGACACAGAGTATGCTTGGGATAAAAATAAAGCTGATCGTTGGATGAATGTTGACCAGTATA
TCGGGGGTGTTGAGCATGCGATCCTGCACCTACTGTATTCCCGGTTTTTTACCAAGGTTTTCTATGATCTGGGTCTGGTG
AATGTACAAGAACCCTTTGAAAACCTACTTACCCAGGGTATGGTTTTAAAGGATGGCAGCAAAATGTCCAAATCAAAGGG
CAACGTGGTAAGTCCAGAAGAAATTATTGACCGCTATGGTGCTGATACTGCAAGGATGTTTATCCTTTTTGCCGCTCCAC
CTGAAAGGGATTTGGAGTGGAGTGACAGGGGGGTAGAAGGAAGCCACCGATTCCTTAACCGTGTATGGCGATTGGTTTAT
TCCCTGAAAGACGAAGTAGCTGGAGCTCCAGCCATTTCAAGTGTTAATGCTTATGTGGGTGTACACAAAGAAATGCGACG
TTTAACTCACTATGCCATTAAAAAGGTAACTGAGGATGTTAGTGGCCGCTTTAACTTTAATACTGCCATCAGTACCATCA
TGGAACTGGTTAATGGAATTTATACCTACCGTGATAAGGTTGCGGCAGTGGAACGGGATACAGCGGTATTGGCCGAAGCC
GTTAACAGTACCATCATTCTACTGGCTCCCTTTGCGCCCCATATTGCCGAGGAACTTTGGTCGGCCACCGGACATCAAGG
CAGTGTGCACAAACAGCCTTGGCTCACCTTTGATAGCGCAGCACTGGTGGAGGACGAAGTGGAGGTTGCTGTTCAAATTA
ATGGTAAAGTTCGGGAAAGGTTAAATATACCTGCCAATATGAAGCCGGCGGAAATGCAGCAATATCTTATGGATATGGAG
TCGGTTAAAATACTGATTGGCGACAAACAAATTGTTAAAATTATTCCGGTTCCAGGCAAATTATTAAACATTGTGGTAAA
ATGA

Protein sequence :
MQEHYDFKEIEKKWQEDWNKENTYQVPDFSERPKYYCLEMFPYPSGKLHMGHVRNYSIGDVVARFKTMQGYDVLHPMGWD
AFGLPAENAAIKHGIAPATWTWDNIAHMRSQLKQLGLSYDWNREVATCHTEYYKWGQWLFLQLYKKGLCYKKHARVNWCP
DCATVLANEQVVDGACERCSAVVEQKELDQWFFRITEYAQRLLNDLKLLKGWPDKVKIMQENWIGRSEGAELTFQVEGSD
ESITVFTTRPDTVYGVSYMVLAPEHPLVAKLIAGRPQEAEVIGFVNRVNKLTELDRTSSDKEGVFTGAYCINPFDGARVP
ILIANYVLYHYGTGAVMGVPAHDERDFEFAHKYNLPIKVVIYPAQDKEIRVEDMKEAYTADGIMVHSGPFDGSPNRQGIK
KVIKYAEEKGIGKGIVNYRLRDWLISRQRYWGTPIPIVYCEKCGTVPVPEDQLPVILPTDVAFKPTGESPLKGRPDFVHT
TCPQCGGPAQRETDTMDTFVDSSWYYLRYTSSRDTEYAWDKNKADRWMNVDQYIGGVEHAILHLLYSRFFTKVFYDLGLV
NVQEPFENLLTQGMVLKDGSKMSKSKGNVVSPEEIIDRYGADTARMFILFAAPPERDLEWSDRGVEGSHRFLNRVWRLVY
SLKDEVAGAPAISSVNAYVGVHKEMRRLTHYAIKKVTEDVSGRFNFNTAISTIMELVNGIYTYRDKVAAVERDTAVLAEA
VNSTIILLAPFAPHIAEELWSATGHQGSVHKQPWLTFDSAALVEDEVEVAVQINGKVRERLNIPANMKPAEMQQYLMDME
SVKILIGDKQIVKIIPVPGKLLNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-165 44