Gene Information

Name : hemC (Dred_2163)
Accession : YP_001113505.1
Strain : Desulfotomaculum reducens MI-1
Genome accession: NC_009253
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2367344 - 2368273 bp
Length : 930 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
ATGAAACATAAAATAACCGTTGGCAGCAGGGACAGTGCGCTGGCACTGTGGCAAACTCGCTGGGTAGTTGAACAGCTGGA
AAAACAAAACCCTGATGTTACCTTTGAAATTACAACCATGAAGACTAAGGGAGACAAAATGTTGGATGTGGCCCTGGCCA
AAATTGGGGATAAAGGTCTATTTACCAAAGAATTAGAAGTGGCTATGTTGCAGAAGGAAATCGATTTTGCAGTGCATAGT
CTGAAGGATATGCCCACTGCTTTGCCAGAAGGCTTAATCATTGGTGCAGTATGCAAGCGAGATAACCCCGGCGATGCACT
GATTTCCAAGGATGGACGGAAATTAGATGAGCTTCCTAAGGGTGCTAGAATCGGTACATCTTCTTTACGCCGCTGTGCGC
AGTTATTAAACTACCGTCCGGATTTTCAACTGGAGGCCCTACGGGGTAACCTGAATACACGTATGAAAAAGTTGGTGTCC
GAGCAACTAGATGGCATTATTCTGGCTGCAGCGGGCATAACCCGCATGGGCTGGGAAGATATGATTGCGGAAATTATTCC
CTTTCAGGTTTGTCTACCGGCAGTGGGACAGGGTGCCATTTCTGTGGAATGTCGGGAGGACGATCCAGAAATTCTTAATC
TACTTAAAGGTATTGAACATACAGAGACCAAAGCTGCCACTGAAGCAGAAAGGTCATTACTCCGTTACTTAGAAGGCGGT
TGCCAGGTGCCCATTGGAGCCCACAGTGAAGTTAAGAATAATAGGCTTATGCTCACCGCTGTTGTGGCCACCCTAGATGG
GACTAAAGTTATTCGGGCCCAAGGAGAGAACGAGGTTAACAAGGCGGTGGAATTAGGTATTGAAGTGGCTGAGAAACTAA
TGGCAATGGGCGGTAAAAAAATACTGGAAGAAGTTAGGGCGGGGGAATGA

Protein sequence : 
MKHKITVGSRDSALALWQTRWVVEQLEKQNPDVTFEITTMKTKGDKMLDVALAKIGDKGLFTKELEVAMLQKEIDFAVHS
LKDMPTALPEGLIIGAVCKRDNPGDALISKDGRKLDELPKGARIGTSSLRRCAQLLNYRPDFQLEALRGNLNTRMKKLVS
EQLDGIILAAAGITRMGWEDMIAEIIPFQVCLPAVGQGAISVECREDDPEILNLLKGIEHTETKAATEAERSLLRYLEGG
CQVPIGAHSEVKNNRLMLTAVVATLDGTKVIRAQGENEVNKAVELGIEVAEKLMAMGGKKILEEVRAGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-61 46
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-61 46