Gene Information

Name : guaB2 (SACE_0914)
Accession : YP_001103173.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 1023411 - 1024850 bp
Length : 1440 bp
Strand : +
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
GTGCAGTTCTTGAACGGGCAGCAGCCCACTACCGACCTGACCTACGACGACGTCTTCCTCGCGCCCCGGCGCTCGGGCGT
CGAGTCCCGGTTCGACGTCGATCTCGCCACCGCCGACGGCACCGGCGCGACCCTGCCGATCGTGGTCGCCAACATGACCG
CGGTCGCCGGCCGCCGGATGGCCGAGACGATCGCCCGGCGCGGCGGACTGGTGGTGCTGCCGCAGGACGTGGCCCCCAGC
GCGGTCGCCGAGATCGTCTCCTGGGTCAAGCAGCGCCATCCGCTCTGGGACACGCCGCTGGTGTTGCACGCCGACGACGC
GGTCGCCGACGCGCTGAACCTCCTCCCCAAGCGCGCCCACGGCGCCGTGGTGGTCGTCGACGACGGCAACCGCCCGGTGG
GCGTGGTCGACGAGGCCGCCTGCGGTGGTGTCGACCGCTTCAGCCGGGTCGGCGAGGTCGCCGACCTCAGCCCGGTGGTG
CTGCCGCTGGAGACCAAGCCGCGCGAGGTGTTCGAGCAGCTCCACAAGCAGGCCAGGAACGTCGCGCTCGCCGTCGACGC
CGACGGTGTGCTCGCGGGGGTCATGACCGCGAAGGCGGCGCTGCGGGCCGAGATCTACACCCCCGCGCTCGACGCCGACG
GCAAGCTGCGCGTCGCGGCGGCTGTCGGGGTGAACGGCGACGTGGCCGCCAAGTCCGAAGCACTGCTGGGCGCGGGTGTG
GACGCGCTGGTCGTCGACACCGCGCACGGCCACCAGGAGAAGATGATCGCCGCGCTCGGCGCGGTGCGCTCGGTGAGCCC
GCGGGTGCCGGTGGTGGCGGGCAACGTGGTCACCGCCGACGGCGTGCGGGACCTGGCCGAGGCCGGGGCCGACGTGATCA
AGGTCGGTGTCGGCCCTGGCGCGATGTGCACGACCCGGATGATGACCGGCGTCGGCCGTCCGCAGTTCTCCGCGGTCGCC
GAGTGCGCCACCGCGGCCCGCGAGCTGGGCAAGCACGTGTGGGCCGACGGCGGCGTGCGCCACCCGCGCGACGTGGCCCT
CGCCCTGGCCGCAGGCGCGGCCTCGGTGATGGTCGGGTCCTGGTTCGCGGGCACCTACGAGTCGCCGGGCGACCTCCAGC
GCGACGAGCACGGCCGCGCCTACAAGGAGTCCTTCGGCATGGCATCGAAGCGGGCCGTGAGCGCGCGGACCCGGTCCGAC
GGCGCCTTCGACCAGGCGCGCAAGGCGCTGTTCGAGGAGGGCATCTCCAGCTCGCGGATGCGGCTGGACCCGCAGCGGCC
GGGCGTGGAGGACCTGCTCGACGAGATCAGCTCCGGCCTGCGTTCGTCGTGCACGTACGCGGGCGCGCGGAGCCTGGAGG
AGTTCCACGAGCGGGCGCTGGTGGGCATCCAGTCGGCGGCCGGTTTCGCCGAGGGCCGTCCGCTGCCGTCCGGCTGGTGA

Protein sequence :
MQFLNGQQPTTDLTYDDVFLAPRRSGVESRFDVDLATADGTGATLPIVVANMTAVAGRRMAETIARRGGLVVLPQDVAPS
AVAEIVSWVKQRHPLWDTPLVLHADDAVADALNLLPKRAHGAVVVVDDGNRPVGVVDEAACGGVDRFSRVGEVADLSPVV
LPLETKPREVFEQLHKQARNVALAVDADGVLAGVMTAKAALRAEIYTPALDADGKLRVAAAVGVNGDVAAKSEALLGAGV
DALVVDTAHGHQEKMIAALGAVRSVSPRVPVVAGNVVTADGVRDLAEAGADVIKVGVGPGAMCTTRMMTGVGRPQFSAVA
ECATAARELGKHVWADGGVRHPRDVALALAAGAASVMVGSWFAGTYESPGDLQRDEHGRAYKESFGMASKRAVSARTRSD
GAFDQARKALFEEGISSSRMRLDPQRPGVEDLLDEISSGLRSSCTYAGARSLEEFHERALVGIQSAAGFAEGRPLPSGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-118 61
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 1e-118 61
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 1e-118 61
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 5e-119 61