Gene Information

Name : metB (SACE_0902)
Accession : YP_001103161.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1012983 - 1014122 bp
Length : 1140 bp
Strand : +
Note : -

DNA sequence :
ATGACCGACGGCTTCGCCACCCGCGCGATCCACGCGGGCCAGGATGCAGACCCGACGACCGGCTCGGTGATCGTGCCGAT
CCACGCGACCTCGACCTACGCCCAGGACGGCGTGGGCGGGATGCGCTCGGGCTACGAGTACTCGCGCACCGGCAACCCGA
CCCGGACGGCGCTGGAGGAGTGTCTTGCCGCGCTGGAAGGCGGCAGGCACGCCAGGGCGTTCGCCTCGGGCATGGCAGCC
ACCGATGCGGTGCTGCGCGCGACGTTGCGTCCTGGCGACCACCTGATCATCCCCGACGACGCCTACGGCGGCACGTTCCG
CCTGATCGACAAGGTGCTGTCGGGCTGGGGTGTGGAGTACACGCCGGTCCCGGTGTCCGATGTGGATGCCGCGCGGGCGG
CGATCCGGGCCAACACCAAGCTGATCTGGATCGAGACCCCCACCAACCCGCTGCTCAACATCGGCGACATCGCCGCGCTG
GCGCAGCTCGCGCACGACACCGGCACGAAGCTGGTCGTGGACAACACCTTCGCCTCGCCGTACCTGCAGCAGCCGCTGGA
GCTCGGGGCGGCCGTCGTCGTGCACTCGACGACCAAGTACCTGGGCGGGCACTCCGACGTGGTCGGCGGCGCCGTGGTGA
CCTCCGACGACGAGCTCGCCCAGCAGGTCGCGTTCCTGCAGAACAGCGCGGGCGCGGTGCCCGGGCCTTTCGACGCGTGG
CTGACGCTGCGCGGGCTGAAGACGCTCGCGGTGCGGATGGACCGCCACAGCGCCAACGCCGAGCGGGTCGTGGCCGCGCT
GCAGAACCACCCCAAGGTCGCCAGGGTGCTCTACCCGGGCCTGGAGGAGCACCCCGGCCACGACGTGGCGGTGAAGCAGA
TGCGCAGCTTCGGCGGGATGGTGTCGTTCATCCACGCCGACGGCGAGCAGGCCGCGCTAGACGTCTGCGCCCGCACCAGG
CTGTTCACCCTGGCCGAGTCGCTGGGCGGGGTGGAGTCGCTGATCGAGCACCCCGGCCGGATGACCCACGCCAGCACGGC
GGGTTCGATGCTGCAGGTGCCCTCCGACCTCGTCCGGCTGTCGGTCGGCATCGAGGACGCAGGCGACCTCGTCGAGGACC
TGCTCAGCGCACTGGACTGA

Protein sequence :
MTDGFATRAIHAGQDADPTTGSVIVPIHATSTYAQDGVGGMRSGYEYSRTGNPTRTALEECLAALEGGRHARAFASGMAA
TDAVLRATLRPGDHLIIPDDAYGGTFRLIDKVLSGWGVEYTPVPVSDVDAARAAIRANTKLIWIETPTNPLLNIGDIAAL
AQLAHDTGTKLVVDNTFASPYLQQPLELGAAVVVHSTTKYLGGHSDVVGGAVVTSDDELAQQVAFLQNSAGAVPGPFDAW
LTLRGLKTLAVRMDRHSANAERVVAALQNHPKVARVLYPGLEEHPGHDVAVKQMRSFGGMVSFIHADGEQAALDVCARTR
LFTLAESLGGVESLIEHPGRMTHASTAGSMLQVPSDLVRLSVGIEDAGDLVEDLLSALD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-80 49
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-81 49
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 3e-63 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metB YP_001103161.1 cystathionine gamma-synthase BAC0207 Protein 6e-62 43