Gene Information

Name : hemC (SACE_6945)
Accession : YP_001109033.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 7761703 - 7762650 bp
Length : 948 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence : 
TTGAACAAGACCCTCCGCATCGGTACCCGGGGCAGCGCGCTGGCGATGGCGCAGACCTCATGGGTGGCCGAAGCGTTGGA
GAAAGCCGGCTACCGCACGGAGCTGGTGACGGTGAGCACGCCGGGGGACCGGTCGATGGCGCCGATCGCCGAGATCGGCG
TGGGCGTGTTCACCTCCGCGCTGCGCGACGCCCTCGCCGACGGTGAGGTCGACGTCGCGGTGCACTCCTACAAGGACTTG
CCGACCGCACCGGACCCGCGGCTGTCGCTGGCCGCCGTTCCGGTTCGCGAGGACCCCCGGGACGCGCTGGTGGCCCGGGA
CGGTCTGACGCTCGGTGAACTGCCCCCGGGCTCCGTCGTGGGCACCGGTTCGCCGCGTCGCGCAGGCCAGCTCAAGGCCC
TCGGCCTCGGGCTGGAGGTGCGCGACATCCGCGGCAACGTGGACACCCGGATGCGCAAGGTGACCGACGGCGAGCTGGAC
GCCGTCGTGCTCGCCCGCGCCGGCCTGGCCCGCGTGGGCCGGCTCGCCGGGATCACGGAAACGCTCGATCCACTGCAGAT
GCTGCCCGCGCCCGCACAGGGCGCGCTGGCAGTGGAATGCCGCGTCGACGACGTGGACACCGAGCACCTGCTGCAGTCCG
TTTTGGACGATCAGGCCAGCCGCGTCGCGGTGGCCGCCGAGCGCGCCATGCTGGCCGCGCTCGAAGCGGGCTGTAGTGCG
CCTGTCGGCGCGCTGGCCGAAGTGGTGGAGGACCTCGACGCAGACGGCCGCGTGGCGCAGCGGCTGTTCGTGCGCGGGGT
GGTGGCTGTCGACGACGCTTCCGGGCGCGTCGACCTGCTGCGCGCCTCCGTCACTGGTGAGACGACCGCCGCTGAGCAGC
TGGGCCGTGAACTGGCCGCCCAGCTGCTCGATGCCAGGGCCGCCCTGCTCAGCGGCCCTGGGCAGTAG

Protein sequence : 
MNKTLRIGTRGSALAMAQTSWVAEALEKAGYRTELVTVSTPGDRSMAPIAEIGVGVFTSALRDALADGEVDVAVHSYKDL
PTAPDPRLSLAAVPVREDPRDALVARDGLTLGELPPGSVVGTGSPRRAGQLKALGLGLEVRDIRGNVDTRMRKVTDGELD
AVVLARAGLARVGRLAGITETLDPLQMLPAPAQGALAVECRVDDVDTEHLLQSVLDDQASRVAVAAERAMLAALEAGCSA
PVGALAEVVEDLDADGRVAQRLFVRGVVAVDDASGRVDLLRASVTGETTAAEQLGRELAAQLLDARAALLSGPGQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-26 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-26 41