Gene Information

Name : guaA (SACE_6701)
Accession : YP_001108792.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 7503589 - 7505175 bp
Length : 1587 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
GTGTCCGGTACCGCTAGCAGCAAGGGGCGGGGCCCCGTCCTCGTCGTCGACTACGGCGCCCAGTACGCGCAGCTCATCGC
GCGCCGGGTGCGGGAAACCCAGATCTATTCCGAGGTGGTCCCGCACGACACGCCCGTCGAGGAGATCGTGCGCCGCGACC
CGGCCGCCATCGTGCTCTCCGGCGGCCCGGCCAGCGTCTACGCCGAGGACGCGCCCCAGATCGACCCGGCACTGTTCGAC
GCGGGCGTGCCGGTGTTCGGCATCTGCTACGGCTTCCAGGCCATGACCGCCGCGCTCGGCGGCACGGTCGAGCACACCGG
CACCCGCGAGTACGGGCGCACCGAGCTGGCGGTCACCGGCGACGGCGGCACGCTGCACGAGGACCTGCCCGGCCACCACC
CGGTGTGGATGAGCCACGGCGACTCGGTGAGCAAGGCCCCGGAGGGCTTCACCGTCACCGCGGGGAGCAAGGACACCCCG
GTCGCGGCGTTCGAGAACGTCGAGCGCGGGCTCGCCGGCGTGCAGTACCACCCGGAGGTCGCGCACTCCCCGCACGGCCA
GGAGGTGCTGCGCCGCTTCCTGCACGAGATCGCAGGCATCCGCCCGGCATGGACCACCTCCTCCATCGTGGACGACACGG
TGGCCGCCATCCGCGAGCAGGTCGGCGACAAGCGCGCGATCTGCGGGCTGTCCGGCGGCGTGGACTCCGCGGTCGCCGCG
GCGCTGGTGCAGCGCGCGGTCGGCGACCAGCTCACCTGCGTCTTCGTCGACCACGGCCTGCTGCGCGCCGGTGAGCGCGC
CCAGGTCGAGCGCGACTTCGTCGCCGCCACCGGCGTCCGGCTGGTCACCATCGACGCGCGCGACCGGTTCCTCGCCGCGC
TGGCCGGGGTGACCGACCCGGAGGAGAAGCGCAAGATCATCGGCCGGGAGTTCATCCGGGTCTTCGAGCAGGCCGCGCGC
GACCTGCAGGCCGAGGCCGGTGCCGAGGGCGAGCAGATCGACTTCCTGGTGCAGGGCACGCTCTACCCGGACGTGGTCGA
GTCCGGCGGCGGCTCCGGCGCGGCCAACATCAAGAGCCACCACAACGTCGGCGGGCTGCCTGAGGACCTGCAGTTCGACC
TGGTCGAGCCGCTGCGCGCGCTGTTCAAGGACGAGGTCCGCCGGGTCGGCCTGGAGCTGGGCCTGCCCGAGACGATCGTG
CACCGCCAGCCCTTCCCCGGCCCCGGCCTGGGCATCCGGATCATCGGCGAGGTGACCGCCGACCGGTTGGAGACGCTGCG
CGCCGCCGACGCCATCGCGCGCGAGGAGCTGACCGCCGCCGGCCTCGACCGCGACATCTGGCAGTGCCCGGTGGTGCTGC
TGGCCGACGTCCGCTCGGTCGGCGTCCAGGGCGACGGCCGCACCTACGGCCACCCGGTCGTGCTGCGCCCGGTCTCCAGC
GAGGACGCGATGACCGCCGACTGGACCCGGCTGCCCTACGACGTGCTGGAACGCATCTCCACCCGGATCACCAACGAGGT
CTCCGAGGTCAACCGGGTCACGCTGGACGTCACGTCCAAGCCGCCGGGCACCATCGAGTGGGAGTGA

Protein sequence :
MSGTASSKGRGPVLVVDYGAQYAQLIARRVRETQIYSEVVPHDTPVEEIVRRDPAAIVLSGGPASVYAEDAPQIDPALFD
AGVPVFGICYGFQAMTAALGGTVEHTGTREYGRTELAVTGDGGTLHEDLPGHHPVWMSHGDSVSKAPEGFTVTAGSKDTP
VAAFENVERGLAGVQYHPEVAHSPHGQEVLRRFLHEIAGIRPAWTTSSIVDDTVAAIREQVGDKRAICGLSGGVDSAVAA
ALVQRAVGDQLTCVFVDHGLLRAGERAQVERDFVAATGVRLVTIDARDRFLAALAGVTDPEEKRKIIGREFIRVFEQAAR
DLQAEAGAEGEQIDFLVQGTLYPDVVESGGGSGAANIKSHHNVGGLPEDLQFDLVEPLRALFKDEVRRVGLELGLPETIV
HRQPFPGPGLGIRIIGEVTADRLETLRAADAIAREELTAAGLDRDIWQCPVVLLADVRSVGVQGDGRTYGHPVVLRPVSS
EDAMTADWTRLPYDVLERISTRITNEVSEVNRVTLDVTSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA NP_938969.1 GMP synthase Not tested Not named Protein 0.0 76
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 3e-141 51
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-141 51
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-141 51