Gene Information

Name : pyk3 (SACE_5720)
Accession : YP_001107830.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 6422165 - 6423526 bp
Length : 1362 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGGCGGAGCTCGTCAGCAGCGGAATGGACGTCGCCCGGCTGAACTTCAGCCACGGCAGCCACACCGATCACCAGCGGGT
CTACGACATGGTCCGGGCCGCGGCCAAGGAGTCCGGCCGCGCCGTGGGCGTCCTGGGTGACCTGCAGGGACCGAAGATCC
GCCTCGGCAAGTTCGCCGCCGGGCCGGTCGAGTGGCGCACCGGCGACGTCGTACGAATCACGGTCGACGATGTCCAGGGC
ACCCACGACCGCGTGTCCACCACCTACAAGGGGCTGGCCTCCGACGCCAAGGTCGGTGACCGGCTCCTGGTCGACGACGG
CAAGGTCGGCCTGGTCGTCAGCGCGGTCGAGGACAACGACGTGGTGTGCGAGGTGACCGAGGGCGGTCCGGTCTCGGACA
ACAAGGGCCTGTCCATGCCCGGCATGGACATCTCGGTGCCCGCCCTGTCGGAGAAGGACGTCGAGGACCTGGAGTTCGCC
CTCCAGCTCGGCGTGGACTTCGTCGCGCTGTCGTTCGTGCGCAGCCCCGCCGACATCGACCTGGTGCACCAGGTGATGGA
CCGGGTCGGGCGCCGGGCGCCGGTGATCGCCAAGCTGGAGAAGCCGGAGGCGGTCGACAACCTCGAGGCCATCGTGCTGG
CCTTCGACGGCATCATGGTCGCGCGCGGCGACCTGGGCGTCGAGGTCCCGCTCGAGCACGTGCCGCTGGTGCAGAAGAAG
GCGATCCGCATAGCGCGGGAGAACGCCAAGCCGGTCATCGTGGCCACCCAGATGCTGGACTCGATGATCCAGAACTCGCG
TCCGACCCGGGCCGAGACCTCCGACGTCGCCAACGCGGTGCTCGACGGCACCGACGCGGTGATGCTCTCCGGCGAGACCA
GCGTCGGGCGCTACCCGGTGGAGACGGTGCAGACGATGGCGCGCATCGTCGAGGCCGTCGAGGCCGGTTCCACCGCGCCG
CCGCCGCTGAGCCACGTCCCGCGCACCAAGCGCGGCGTGATCTCCTACGCCGCCCGCGACATCGGGGAGCGGCTCAACGC
CAAGGCGCTGGTGGCGTTCACGCAGTCCGGCGACACCGTGCGAAGGCTCGCGCGGCTGCACACCCGGCTGCCTCTGCTGG
CCTTCACCCCCGAGGAGTCGGTGCGCAGTCAGCTCGCTCTCACTTGGGGGACGGAGACGTTCCTCGTGCCTAAGGTGGAC
ACGACCGACCAGATGGTACGGCAGGTGGACCAGGCGATGCTGTCGCTGGGACGTTCCCAGCGGGGCGACATGGTCGTCAT
CGTCGCGGGTTCGCCGCCGGGCACCGTCGGGTCGACCAACCTGATCCGTGTGCACCGGCTGGGCGAGGAAGACCACATCT
GA

Protein sequence :
MAELVSSGMDVARLNFSHGSHTDHQRVYDMVRAAAKESGRAVGVLGDLQGPKIRLGKFAAGPVEWRTGDVVRITVDDVQG
THDRVSTTYKGLASDAKVGDRLLVDDGKVGLVVSAVEDNDVVCEVTEGGPVSDNKGLSMPGMDISVPALSEKDVEDLEFA
LQLGVDFVALSFVRSPADIDLVHQVMDRVGRRAPVIAKLEKPEAVDNLEAIVLAFDGIMVARGDLGVEVPLEHVPLVQKK
AIRIARENAKPVIVATQMLDSMIQNSRPTRAETSDVANAVLDGTDAVMLSGETSVGRYPVETVQTMARIVEAVEAGSTAP
PPLSHVPRTKRGVISYAARDIGERLNAKALVAFTQSGDTVRRLARLHTRLPLLAFTPEESVRSQLALTWGTETFLVPKVD
TTDQMVRQVDQAMLSLGRSQRGDMVVIVAGSPPGTVGSTNLIRVHRLGEEDHI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 3e-68 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-68 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 4e-68 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk3 YP_001107830.1 pyruvate kinase VFG0479 Protein 1e-68 41