Gene Information

Name : thiC (SACE_0511)
Accession : YP_001102783.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 565000 - 566643 bp
Length : 1644 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
TTGGCCGACGTGCGCCCGAACCTGTCCAGCGACCACCACAGCGTGACCACCGGGCCCATCAGCGGCTCGCGGAAGGTCCA
CCACACCACCGAATCCGGCCTCAAGGTGCCGTTCCGCCGCATCGAGCTGTCCAACGGCGAGCACCTCGACGTCTACGACA
CCTCCGGCGCCTACACCGACGACGACGTGCAGGTCGACGTCCACAGCGGACTCCACCGGCTGCGGGCGGGCTGGACCGAC
GGCCGCGAGCACCGCACCCAGCTCGGCTGGGCCAAGGCCGGTGTGGTGACGCGGGAGATGGAGTTCATCGCCGCCCGCGA
GGGGGTCTCGCCGGAGTTCGTCCGCGACGAGGTCGCCAGCGGTCGCGCCGTGATCCCGGCCAACCGCTGCCACCCGGAGA
GCGAGCCGATGATCATCGGCAAGAACTTCCTGGTGAAGGTCAACGCCAACATCGGCAACTCCGCGGTGACCTCCTCGGTC
GAGGAGGAGGTCGAGAAGATGGTGTGGGCGACCCGCTGGGGCGCCGACACCGTGATGGACCTGTCCACCGGGAAGCGGAT
CCACGAGACCCGCGAGCAGATCCTGCGCAACTCGCCGGTGCCGATCGGCACCGTGCCGATCTACCAGGCGCTGGAGAAGG
TCAACGGCGACCCGGAGAAGCTCACCTGGGAGATCTACCGGGACACCGTGATCGAGCAGTGCGAGCAGGGCGTGGACTAC
ATGACCGTGCACGCGGGCGTGCTGCTGCGGTACGTGCCGCTCACCGCGCAGCGGGTCACCGGCATCGTCTCCCGCGGCGG
CTCGATCATGGCGGCCTGGTGCCTGGCGCACCACCGCGAGAGCTTCCTCTACACGCACTTCTCCGAGCTGTGCGAGATCC
TGCGCGACTACGACGTCACCTTCTCCCTCGGCGACGGCCTGCGTCCCGGCTCGATCGCCGACGCCAACGACCGGGCGCAG
TTCGCCGAGCTGGAGACCCTCGGCGAGCTGACCCACATCGCCCGCGACATGGACGTGCAGGTGATGATCGAGGGCCCCGG
CCACGTCCCGATGCACAAGATCGTGGAGAACGTGAAGCTGGAGGAGGAGCTGTGCGGTGAGGCGCCGTTCTACACGCTCG
GCCCGCTGACCACCGACATCGCGCCCGCCTACGACCACATCACCTCCGGCATCGGCGCGGCGGTGATCGCCCAGGCGGGC
ACGGCGATGCTCTGCTACGTCACGCCGAAGGAGCACCTGGGACTGCCCAACCGCGACGACGTGAAGGTCGGCGTCATCAC
CTACAAGATCGCCGCGCACGCCGCCGACCTCGCCAAGGGCCACCCCCGCGCGCAGGACTGGGACGACGCGCTGTCCAAGG
CCCGCTTCGAGTTCCGGTGGAACGACCAGTTCAACCTGTCGCTGGACCCGGACACGGCGCGCGCGTACCACGACGAGACC
CTGCCCGCCGAGCCCGCCAAGACCGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGAAGATCACCCAGGA
CGTGCGCAAGTACGCCGAGGAGCGCGGGCTGACCAGCGTCGAGGCGATCGAGGCCGGGATGCGGGAGAAGTCCGACGAGT
TCTCCGAGTCCGGCGGCAAGGTCTACCTGCCGGTGGTCGGCTGA

Protein sequence :
MADVRPNLSSDHHSVTTGPISGSRKVHHTTESGLKVPFRRIELSNGEHLDVYDTSGAYTDDDVQVDVHSGLHRLRAGWTD
GREHRTQLGWAKAGVVTREMEFIAAREGVSPEFVRDEVASGRAVIPANRCHPESEPMIIGKNFLVKVNANIGNSAVTSSV
EEEVEKMVWATRWGADTVMDLSTGKRIHETREQILRNSPVPIGTVPIYQALEKVNGDPEKLTWEIYRDTVIEQCEQGVDY
MTVHAGVLLRYVPLTAQRVTGIVSRGGSIMAAWCLAHHRESFLYTHFSELCEILRDYDVTFSLGDGLRPGSIADANDRAQ
FAELETLGELTHIARDMDVQVMIEGPGHVPMHKIVENVKLEEELCGEAPFYTLGPLTTDIAPAYDHITSGIGAAVIAQAG
TAMLCYVTPKEHLGLPNRDDVKVGVITYKIAAHAADLAKGHPRAQDWDDALSKARFEFRWNDQFNLSLDPDTARAYHDET
LPAEPAKTAHFCSMCGPKFCSMKITQDVRKYAEERGLTSVEAIEAGMREKSDEFSESGGKVYLPVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 1e-166 63
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 1e-166 63