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Name : lysS (SACE_4738) Accession : YP_001106931.1 Strain : Saccharopolyspora erythraea NRRL 2338 Genome accession: NC_009142 Putative virulence/resistance : Unknown Product : lysyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG1190 EC number : 6.1.1.6 Position : 5296227 - 5299523 bp Length : 3297 bp Strand : + Note : catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA DNA sequence : GTGGAGCATGCGCGGCGGTTCCGGTGGCGCGACCGCGTCCCGGGCGCGGCCGCGGGGCTCGTGTTCGCGATCGCCCTGCT GTGCTCGTTCGCGGCCGTCGGCCTGGTGCTGCACGGCCACGTCCAGCCGGTGCGCCGGTTCGTCGACGACGTCGTCTTCC CCGCCCCGCCCAACCTCGCCTACGGGGCCTTCCTGGTGGTGCTCGCGGCGGCGCTGAAGCGGCGCAAGTGGGTCGCGCAC CGGATTCTCGCGGCGATCGTGCTGCTCCAGCTGCTCGTGGACCTGGCGGTGCTGTTGGCCGCGGGCGGCGAGGGTTCGCT GTGGATCGACGAGATGGGCACGTTGCGGCAGGTGCCGGTCAGCCCGTGGCCGTTCGGGGTGAACGTCGCGGTGAGCCTCG CCGCGCTGACGCTGCTGGTGTGGGCGCGGGGCGAGTTCTACGGGCGCACCGGCACCGGCAGCGTCCGCCGCGCGGCGGCC ACCTTCTGCGGACTCGTCGCGGCGTCCGTGGCGCTGGGCTTCGGCCTGGTGACGGTGTTCCCCGGTTCGCTGGACGACCC GCGGGAACGCCTGACCTGGACGGTGGAGCGGGTGCTGGGCGGCGCGGTGGTCTTCGACGTCACCCGCGTCGGCCACGCCC CGGGCTGGGTCAACCTGCTGCTCGGGCTGTTCGGCAGCGCCGCGCTGTTCGCGACGCTGTTCGTCCTCTTCGCCGCCCAG CGGGTGGCCGCGGCGCTGACGCCCGAGCAGGAGCAGCGGATCCGGCAGCTGCTGGACGACCGCGACGGCGACTCGCTGGG CTACTTCGCCACCAGGCGCGACCGGTCGGCGCTGTTCTCGGCCAGCGGCAAGGCGGCGATCAGCTACCGTCCGGTCGCCG GGGTGTGCCTGGCGGGCGGCGACCCGGTCGGCGACCGCGAGGCGTGGGCCCCGGCGATCCAGGACTGGCTGGCGATGTGC CGGGAGTACACCTGGATGCCCGCGGCGATGGGGCTCAGCGAGCCCGCTGCCGCCGCGTTCGCCCGGGCCGGGCTGAAGGT GCTGCAACTTGGCGACGAGGCGGTGCTGCACACCGCCGAGTTCGGCCTGGCGGGCCGGGACATGCGACCGGTGCGGCAGG CGGTCAACCGGGTCCACCGCGCCGGGTACCGCACGCGCGTCAGGCGGCATCGGGACGTGCCTGGAGCCGAGATGCGCGAG ATCGTCGAACTGGTCGACCGGTGGCGCACCAGCGGCACCGAGCGCGGCTTCTCGATGGCGCTGGGCAGGCTCGGCGACCC GCAGGACGGCGACTGCGTGCTCGTGGAGGCCGTCGGACCGGACGGACGGCGGCACGCCCTGCTGTCGCTGGTCCCGTGGG GCCGCGACGGTCTGTCGCTGGACCTGATGCGCCGCGATCCGGACGCCGACAACGGGCTGGTCGAGCTGATGGTCTCGGGC CTGATGCGCACGGCGCCGGTACTCGGTGTGACGCGGGTGTCGCTGAACTTCGCGGTGTTCCGCTCGGCGTTCGAGGAAGG CGCGCGGCTGGGCGCGGGCCCGGTGCTGCGGGCTTGGCGGGGACTGCTGCTGTTGCTGTCGCGCTGGTGGCAGCTGGAGT CGCTGTACCGGTCGAACGTGAAGTACCAGCCGCACTGGTATCCCCGCTACATCGCCTTCGCCGAGCACCGCGAGCTCGCC CGCGTGGGCCTGGCCTCGGCCATCGCCGAGGGCTTCGTACCCGCCTTCGGCCACCGCCGGGCGATGACGGTGTCCGGCGC GCGGCCCGAGGCCTCGGCGACGGCGCCGACCGCACCGCAGCCGACCGCCGAACCGGAGCAGCAGCAGGTGCGGCGGCGCA AGCTCGCCGAGCTCCGCGAGGCAGGCGTCGACCCGTACCCGCCCGAGGTGCCCCGCACGCAACCGTGCCGCGCGGTGGCC GAGCACCACGGTGGGCTGGAGCCCGGAACCCGCACCGGCGAGACCACGTCGGTGGCCGGCCGGGTGATGCGCCTGCGAGA CCACGGCGGCCTGTGCTTCGCGACCGTGCGCGACTGGTCCGGCGACCTCCAGGTGCTGCTCACCGCCGACGACAGCGGCC ACGACCTGCTGGTGGCCTGGCGCGGCGAGGTCGACCTCGGCGACCAGGTGTCGGTGACCGGAGAGGTGGTGACCTCCGAC CGCGGCGAGCTGACGGTGCTGGCCAAGAGCTGGACCCTGGCGGGCAAGTGCCTGCACCCGCTGCCCGACAAGCACCGCGG TCTGTCCGATCCGCACTCGCGCGTCCGCGCCCGCCACCTCGACCTGATCACGCGGCCGGAGGCGCGCTCCGTGCTGCGGG CGCGCAGCGCGGCCACCCACGCGCTGCGGGACGTGCTCGTGCGGTCCGACTTCGTCGAGGTCGAGACGCCGGTGCTGCAA CCGGTCCGCGGCGGGGCGAACGCGCGGCCGTTCAGCACCCACATCAACGCCTACGACCTGCGCCTGTACCTGCGGATCGC CCCGGAGCTCTACCTCAAACGGCTCTGCGTCGGCGGCGTCGAGCGGCTGTTCGAGATCGGCCGGGCGTTCCGCAACGAAG GCGTGTCGCACAAGCACAACCCGGAGTTCACGATGCTGGAGGCCTACCAGGCGTTCGGCGACTACACCACGATGCGCGAG CTGTGCCGGGAGCTGGTGGTGGCCGCCGCGGTCGCCGCGACCGGTTCGACCGTCGTGACCGGCCGCGACCGGCTCGGCCG CGATGTCGCGACCGACCTCGCGGACGACTGGCCGGTGATCGGCGTGCACGAGGCGGTGTCGGCCGCGACCGGCGAGGAGG TCACCGCGGACACACCCGTGCGACGGCTCCGGCGCCTCTGCGACGACAACGGCATCGCGCACCTGCGGGACTGGGGACGC GGGGCGGTGCTGCTGGAGCTCTACGAGCGGTTGGTGGAGGCCGAGACCACCGGGCCGACCTTCTACCGCGACTTCCCGGC CGAGGTCTCGCCGCTGGCCCGCCCGCACCGCCACGACGCCAGGCTTGCCGAGCGCTGGGACCTGGTCGCCTTCGGTACCG AGCTCGGCACCGGCTACTCGGAGCTGACAGACCCGGTGGAGCAGCGGCGGCGGCTGGCCGACCAGGCCCGGCTCGCCGCC GAGGGCGACGCCGAGGCCATGGACGTCGACGAGGACTTCCTCACCGCGCTGGAGTACGCCATGCCGCCCACCGGCGGCCT CGGGCTCGGCGTCGACCGCCTGGTCATGCTGCTCACCGGCCGCTCCATCCGCGACACGCTCGCCTTCCCGCTGGTCAAGC CGCAACGCGCGACCTGA Protein sequence : MEHARRFRWRDRVPGAAAGLVFAIALLCSFAAVGLVLHGHVQPVRRFVDDVVFPAPPNLAYGAFLVVLAAALKRRKWVAH RILAAIVLLQLLVDLAVLLAAGGEGSLWIDEMGTLRQVPVSPWPFGVNVAVSLAALTLLVWARGEFYGRTGTGSVRRAAA TFCGLVAASVALGFGLVTVFPGSLDDPRERLTWTVERVLGGAVVFDVTRVGHAPGWVNLLLGLFGSAALFATLFVLFAAQ RVAAALTPEQEQRIRQLLDDRDGDSLGYFATRRDRSALFSASGKAAISYRPVAGVCLAGGDPVGDREAWAPAIQDWLAMC REYTWMPAAMGLSEPAAAAFARAGLKVLQLGDEAVLHTAEFGLAGRDMRPVRQAVNRVHRAGYRTRVRRHRDVPGAEMRE IVELVDRWRTSGTERGFSMALGRLGDPQDGDCVLVEAVGPDGRRHALLSLVPWGRDGLSLDLMRRDPDADNGLVELMVSG LMRTAPVLGVTRVSLNFAVFRSAFEEGARLGAGPVLRAWRGLLLLLSRWWQLESLYRSNVKYQPHWYPRYIAFAEHRELA RVGLASAIAEGFVPAFGHRRAMTVSGARPEASATAPTAPQPTAEPEQQQVRRRKLAELREAGVDPYPPEVPRTQPCRAVA EHHGGLEPGTRTGETTSVAGRVMRLRDHGGLCFATVRDWSGDLQVLLTADDSGHDLLVAWRGEVDLGDQVSVTGEVVTSD RGELTVLAKSWTLAGKCLHPLPDKHRGLSDPHSRVRARHLDLITRPEARSVLRARSAATHALRDVLVRSDFVEVETPVLQ PVRGGANARPFSTHINAYDLRLYLRIAPELYLKRLCVGGVERLFEIGRAFRNEGVSHKHNPEFTMLEAYQAFGDYTTMRE LCRELVVAAAVAATGSTVVTGRDRLGRDVATDLADDWPVIGVHEAVSAATGEEVTADTPVRRLRRLCDDNGIAHLRDWGR GAVLLELYERLVEAETTGPTFYRDFPAEVSPLARPHRHDARLAERWDLVAFGTELGTGYSELTDPVEQRRRLADQARLAA EGDAEAMDVDEDFLTALEYAMPPTGGLGLGVDRLVMLLTGRSIRDTLAFPLVKPQRAT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| lysX | YP_003784331.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 5e-152 | 46 |
| lysS1 | YP_005686365.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 5e-152 | 46 |
| lysS1 | YP_005682181.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 2e-151 | 46 |
| lysS1 | YP_005684273.1 | lysyl-tRNA synthetase | Not tested | PiCp 7 | Protein | 5e-152 | 46 |
