Gene Information

Name : clpC (SACE_0414)
Accession : YP_001102688.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 463959 - 466520 bp
Length : 2562 bp
Strand : +
Note : -

DNA sequence :
ATGTTCGAGAGGTTCACCGACCGCGCGAGGCGGGTGGTCGTCCTGGCCCAGGAAGAGGCCCGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATCCTCCTGGGCTTGATCCACGAGGGTGAGGGTGTCGCCGCCAAGGCGCTGGAGTCGCTGGGTA
TCGCGCTTGAGGGCGTGCGCCAGCAGGTCGAGGAGATCATCGGCCAGGGTCAGCAGGCTCCGAGCGGTCACATCCCGTTC
ACCCCGCGGGCCAAGAAGGTGCTGGAGCTGTCGCTGCGCGAGGCGCTGCAGCTGGGGCACAACTACATCGGGACCGAGCA
CATCCTGCTCGGCCTGATCCGCGAGGGCGAGGGCGTGGCCGCGCAGGTGCTGGTCAAGCTCGGCGCGGACCTCAACCGGG
TTCGCCAGCAGGTGCTGCAGCTGCTGTCGGGTTACCAGGGCAAGGAGCCGGCGGAGGCCGGCGGCCGCGGCGAGGGAACC
CCGTCGTCGTCGCTGGTGCTGGACCAGTTCGGCCGCAACCTGACGCAGAGCGCCCGCGAGTCCAAGCTCGACCCGGTCAT
CGGTCGCGAGAAGGAGATCGAGCGGATCATGCAGGTCCTCTCGCGGCGCACCAAGAACAACCCGGTGCTCATCGGCGAGG
CGGGCGTCGGCAAGACCGCCGTGGTCGAGGGCCTGGCGCAGAAGGTCGTCAAGGGCGAGGTGCCCGAGACGCTGAAGGAC
AAGCAGCTCTACACCCTCGACCTGGGTTCGCTGGTCGCGGGTTCGCGCTACCGCGGTGACTTCGAGGAGCGCCTGAAGAA
GGTGCTCAAGGAGATCAAGACCCGCGGCGACATCATCCTGTTCATCGACGAGATCCACACCCTGGTGGGTGCGGGTGCCG
CCGAGGGCGCCATCGACGCGGCGAGCATCCTCAAGCCGATGCTGGCCCGCGGCGAGCTCCAGACGATCGGTGCGACCACG
CTGGAGGAGTACCGCAAGTACGTCGAGAAGGACCCGGCGCTGGAGCGCCGCTTCCAGCCGATCCAGGTCGGCGAGCCCTC
GCTGGAACACACCATCGAGATCCTCAAGGGCCTGCGCGACCGGTACGAGGCGCACCACCGGGTGTCCATCACCGACGGCG
CGCTGGTCTCGGCCGCGACGCTGGCCGACCGCTACATCAACGACCGCTTCCTGCCGGACAAGGCGATCGACCTGATCGAC
GAGGCCGGCGCCCGGATGCGCATCCGCCGCATGACCGCTCCGCCGGACCTGCGCGAGTTCGACGAGAAGATCGCCGACGT
GCGCCGGGACAAGGAGTCCGCGATCGACGCGCAGGACTTCGAGCGGGCCGCCCGCCTGCGCGACGAGGAGAAGCAGCTCC
TCGGGCAGAAGGACGAGCGCGAGAAGCAGTGGAAGGCAGGCGACCTCGACGTCGTCGCCGAGGTGGATGACGAGCAGATC
GCCGAGGTGCTGGCGAACTGGACGGGGATTCCGGTGTTCAAGCTCACCGAGGAGGAGACCACGCGTCTGCTCCGCATGGA
GGACGAGCTGCACAAGCGGATCATCGGCCAGGACGACGCGGTCAAGGCGGTCTCGCAGGCGATCCGGCGTACCCGTGCGG
GGTTGAAGGACCCCAAGCGCCCGTCGGGGTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACCGAGCTGTCCAAG
GCGCTGGCGGAGTTCCTGTTCGGCGACGACGACGCGCTGGTGCAGATCGACATGGGCGAGTTCCACGACCGCTACACCGC
CTCGCGGCTGTTCGGTGCCCCGCCCGGCTACGTCGGCTACGAGGAGGGCGGCCAGCTCACCGAGAAGGTGCGTCGCAAGC
CGTTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCCCACCAGGAGATCTACAACACGCTGTTGCAGGTGTTGGAGGAC
GGGCGTCTGACCGATGGTCAGGGGCGCACGGTGGACTTCAAGAACACGGTGCTGATCTTCACCTCGAACCTGGGTACCCA
GGACATCTCCAAGGCCGTGGGGCTGGGCTTCTCGGCCGGGACCGACTCCGAGTCCAACTACGAGCGGATGAAGAGCAAGG
TCAACGAGGAGATGAAGAAGCACTTCCGGCCGGAGTTCCTCAACCGCATCGACGACGTGATCGTGTTCCACCAGCTCACC
GAGGCCGAGATCATCCAGATGGTCGACCTGCTCGGTGCGAGGGTGGAAAAGGCCCTCAAGGGCAAGGACATGTCGCTGGA
GCTGACCACGCTGGCCAAGAAGCTGCTGGCCAAGCGCGGGTTCGACCCGGTGCTGGGGGCCCGGCCGTTGCGCCGGACCA
TCCAGCGCGAGATCGAGGACAGGCTCTCGGAGAAGATCCTGTTCGGCGAGATCGAGCCCGGCCAGATCGTCATCGTCGAC
GTCGAGGGCTGGGACGGCGAGGGCTCCGACGACAAGGCCCACTTCACCTTCCGCGGTGAGACCAAGCCGTCGCTGGTGCC
CGACGCCCCACCGGTCGACCTCGCCGGCTCCACCGGCTCGTCGACCGACGACAAGTCGGAAGGCACCTCCGACCAGGAGT
GA

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKALESLGIALEGVRQQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGADLNRVRQQVLQLLSGYQGKEPAEAGGRGEGT
PSSSLVLDQFGRNLTQSARESKLDPVIGREKEIERIMQVLSRRTKNNPVLIGEAGVGKTAVVEGLAQKVVKGEVPETLKD
KQLYTLDLGSLVAGSRYRGDFEERLKKVLKEIKTRGDIILFIDEIHTLVGAGAAEGAIDAASILKPMLARGELQTIGATT
LEEYRKYVEKDPALERRFQPIQVGEPSLEHTIEILKGLRDRYEAHHRVSITDGALVSAATLADRYINDRFLPDKAIDLID
EAGARMRIRRMTAPPDLREFDEKIADVRRDKESAIDAQDFERAARLRDEEKQLLGQKDEREKQWKAGDLDVVAEVDDEQI
AEVLANWTGIPVFKLTEEETTRLLRMEDELHKRIIGQDDAVKAVSQAIRRTRAGLKDPKRPSGSFIFAGPSGVGKTELSK
ALAEFLFGDDDALVQIDMGEFHDRYTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNTLLQVLED
GRLTDGQGRTVDFKNTVLIFTSNLGTQDISKAVGLGFSAGTDSESNYERMKSKVNEEMKKHFRPEFLNRIDDVIVFHQLT
EAEIIQMVDLLGARVEKALKGKDMSLELTTLAKKLLAKRGFDPVLGARPLRRTIQREIEDRLSEKILFGEIEPGQIVIVD
VEGWDGEGSDDKAHFTFRGETKPSLVPDAPPVDLAGSTGSSTDDKSEGTSDQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 80
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 5e-95 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_001102688.1 ATP-dependent Clp protease VFG0079 Protein 0.0 61
clpC YP_001102688.1 ATP-dependent Clp protease VFG0080 Protein 1e-142 48