Gene Information

Name : thcA (SACE_2915)
Accession : YP_001105118.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Virulence
Product : aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.3
Position : 3194361 - 3195884 bp
Length : 1524 bp
Strand : -
Note : -

DNA sequence :
ATGGCTCTGTACGAAGCTCCGGGTACGGCGGGTTCGGTCGTGGAGTACCGCTCGCGCTACGACCACTTCATCGGTGGCGA
GTACGTGGCCCCGGCCGGGGGCGAGTACTTCGAGAACCCCACCCCGGTCACCGGCAAGACGTTCACCGAGATCGCCCGCG
GCACCGCAGACGACGTCGAACGCGCGCTGGACGCCGCCGAGGGCGCCGCGCCGGCGTGGGGCCGCACCCCGGCGGCCGAG
CGGGCAGGAGTCCTGCTGCGGATCGCCGACCGGATGGAGCACAACCTCGAAAAGCTCGCGGTCGCCGAGAGCTGGGAGAA
CGGCAAGCCGGTGCGCGAGACGCTGGCCGCCGACCTGCCGCTGGCCATCGACCACTTCCGCTACTTCGCCGGGGCGCTGC
GCGCCCAGGAGGGCTCGATCTCCCAGATCGACGAGGACACCGTCGCCTACCACTTCCACGAGCCGCTGGGCGTGGTCGCC
CAGATCATCCCGTGGAACTTCCCGCTGCTGATGGCCACCTGGAAGCTCGCGCCCGCGCTGGCCGCGGGCAACGCCGTGGT
CCTCAAGCCCGCCGAGCAGACCCCGGCCTCGATCCACGTGCTACTCGACCTGATCGCCGACCTGCTGCCCGCCGGCGTGC
TCAACGTGGTCAACGGCTTCGGCGTGGAGGCCGGCAAACCGCTGGCCTCCAGCCCGCGGGTGCGCAAGGTCGCCTTCACC
GGCGAGACCACCACCGGCAGGCTGATCCTGCAGTACGCCAGCCAGAACATCATCCCGGTCACCGTCGAGCTCGGCGGCAA
GAGCCCGAACATCTTCTTCGACGACGTCGCCGCCCAGCAGGACGCCTTCTACGACAAGGCACTGGAAGGCTTCACCATGT
TCGCCCTCAACCAGGGCGAGGTCTGCACCTGCCCGTCGCGGGCGCTGATCCAGTCCGGCATCTACGAGGGCTTCCTGTCC
GACGCCGTCGCGCGCACCGAGCGGATCAAGCAGGGCAACCCGCTGGACACCGACACCCAGATCGGCGCCCAGGCCAGCAA
CGACCAGCTCGAGAAGATCCTGTCCTACATCGACATCGGCAGGCAGGAAGGCGCCGAAGTCCTCACCGGCGGCCACCGCG
TCGAGCTGGAAGGCGACCTGGCGGGCGGCTACTACGTCGCGCCCACCATCTTCCAGGGCCACAACAAGCAGCGCATCTTC
CAGGAAGAGATCTTCGGCCCCGTCGTCTCGGTCGCGAAGTTCGACGACTACGCCGACGCGATGAACACCGCCAACGACAC
CCTCTACGGTCTGGGCGCCGGCGTGTGGTCGCGCAACGCCGGCACCGCCTACCGGGCCGGACGCGACATCCAGGCGGGCC
GGGTGTGGGTCAACAACTACCACGCCTACCCCGCCCACGCCGCCTTCGGCGGCTACAAGCAGTCCGGCATCGGCCGCGAG
ACCCACAAGATGATGCTCGACCACTACCAGCAGACCAAGAACATGCTGGTCAGCTACTCCGAGAACGCGATGGGGTTCTT
CTGA

Protein sequence :
MALYEAPGTAGSVVEYRSRYDHFIGGEYVAPAGGEYFENPTPVTGKTFTEIARGTADDVERALDAAEGAAPAWGRTPAAE
RAGVLLRIADRMEHNLEKLAVAESWENGKPVRETLAADLPLAIDHFRYFAGALRAQEGSISQIDEDTVAYHFHEPLGVVA
QIIPWNFPLLMATWKLAPALAAGNAVVLKPAEQTPASIHVLLDLIADLLPAGVLNVVNGFGVEAGKPLASSPRVRKVAFT
GETTTGRLILQYASQNIIPVTVELGGKSPNIFFDDVAAQQDAFYDKALEGFTMFALNQGEVCTCPSRALIQSGIYEGFLS
DAVARTERIKQGNPLDTDTQIGAQASNDQLEKILSYIDIGRQEGAEVLTGGHRVELEGDLAGGYYVAPTIFQGHNKQRIF
QEEIFGPVVSVAKFDDYADAMNTANDTLYGLGAGVWSRNAGTAYRAGRDIQAGRVWVNNYHAYPAHAAFGGYKQSGIGRE
THKMMLDHYQQTKNMLVSYSENAMGFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 2e-153 62
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 2e-159 60
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 2e-159 60
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 2e-159 60
aldA-1 YP_001216300.1 aldehyde dehydrogenase Not tested VPI-1 Protein 7e-159 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
thcA YP_001105118.1 aldehyde dehydrogenase VFG0082 Protein 1e-153 62