Gene Information

Name : tkt (SACE_2160)
Accession : YP_001104391.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 2345469 - 2347505 bp
Length : 2037 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
TTGGACCAGCGCGCCGTGGACACGGCCCGGGTGCTGGCCGCCGACGCGGTCGAGAACTGCGGGAGCGGGCACCCAGGCAC
CGCGATGAGCCTGGCCCCCGCCGCCTACGCGCTGTTCCAGCGCGTCATGAGGCACGACCCCAGCGACGCCGAGTGGATCG
GCCGCGACCGGTTCGTGCTCTCCGCCGGGCACTCGAGCCTCACCCTGTACGTGCAGCTCTTCCTCTCCGGCTACGGCCTG
GAGCTGGACGACCTCAAGGCGCTGCGCAAGTGGGACTCGAAGACCCCGGGCCACCCCGAGTACGGCCACACCACGGGCGT
GGAGACCACCACCGGCCCGCTCGGCCAGGGCCTGGCGACCGCGGTCGGCATGGCGATGGCCTCCCGCCGCGAGCGCGGGC
TCTTCGACCCCGAAGCCGCTGCGGGTGAGAGCGTCTTCGACCACCACATCTACGTCATCGCCTCCGACGGCGACATCGAG
GAGGGCGTGACCTCCGAGGCGTCGTCGCTGGCGGGCACCCAGCAGCTCGGCAACCTCACGGTGATCTACGACGCCAACGA
GATCTCCATCGAGGACGACACCCGCATCGCGCTGTCGGAGGACACCGCCAAGCGCTACGAGGCCTACGGCTGGCAGGTCC
TGACCGTGCACGGCGGCGAGGACGTGACCGGTCTGCTCGAGGCGATCGAGACCGCCAAGGCCGAGACCAGCCGCCCGACG
CTGATCGTGCTGCGCACGGTGATCGGCTACCCGGCGCCGACCAAGATGAACACCGGCAAGGCCCACGGCGCCGCGCTCGG
TGCCGAGGAGGTCGCCGGGGTCAAGCAGGCGCTGGGCTTCGACCCGGAGCAGTCCTTCGAGGTCGCCCCCGAGGTGCTCG
AGCACGCCCGCAAGGTCGCCGAGCGCGGCAAGGCCGCCCACGAGAAGTGGCAGGTCGAGTTCGAGGCGTGGGCGCAGGCC
AACCCGGAGCGCAAGGCGCTGCTGGACCGCCTGAGCAAGCGCGAACTGCCCGCGGGCTGGCAGGAGAAGCTGCCCACCTA
CGAGGTCGGCGGCAAGGCCGTCGCCACCCGCAAGGCCTCCGGTGAGGTCCTGGCGGCGCTGGCCGACGTGCTGCCCGAGC
TGTGGGGCGGTTCGGCCGACCTCGCCGAGAGCAACAACACCACCATGAAGGGCGTGGAGTCCTTCGGCCCCGCCGAGATC
TCCACCGGCACCTGGACCGCCCAGCCCTACGGCCGGACGCTGCACTTCGGCATCCGCGAGCACGCGATGGGCTCGATCCT
CAACGGCATCGCGCTGCACGGCGGCACCCGTCCCTACGGCGGCACCTTCCTCATCTTCAGCGACTACATGCGGCCCGCGG
TGCGGCTCGCGGCGCTGATGAAGACCCCGGTCGTCTACGTGTGGACCCACGACTCGATCGGCCTGGGCGAGGACGGCCCG
ACCCACCAGCCGATCGAGCAGCTCGCCTCGCTGCGCGCCATCCCCGGCCTGTCGGTGGTCCGCCCGGCCGACGCCAACGA
GACCGCCGCGGCCTGGAAGGCGATCCTGGAGGACACCAGCGGCCCCGCCGGCCTGGCGCTGACCCGCCAGGGCGTGCCGA
CCCTGGAGGGCACCGACGCCGAGGGCGTGGCCCGCGGCGGCTACGTGCTGGCCGAGGCCGGCTCGGGCGAGCCCGACCTG
GTGATCATCGCCACCGGTTCCGAGGTCGAGCTGGCCGTGGCGGCCAGGAAGACCCTGGAGGCCGACGGCGTTGCAACCCG
TGTGGTGTCGATGCCGTGCGTGGAGTGGTTCGACGCGCAGGACGAGGCCTACCGCGAGCAGGTGCTGCCGCGGGGCGTGC
GCGCCCGGGTGGTCGTCGAGGCCGGTATCGCGCAGCCGTGGTACCGCTTCGCCAAGGACAGCGGCGAGATCGTCTCGATC
GAGCACTTCGGCGCCTCGGCGGACTACAAGACCCTGTTCAAGGAGTTCGGGTTCACCGCCGACGCCGTGGTCGCCGCGGC
GCGCCGGAGCCTGGACAACGCACGCGCCAACGCGTGA

Protein sequence :
MDQRAVDTARVLAADAVENCGSGHPGTAMSLAPAAYALFQRVMRHDPSDAEWIGRDRFVLSAGHSSLTLYVQLFLSGYGL
ELDDLKALRKWDSKTPGHPEYGHTTGVETTTGPLGQGLATAVGMAMASRRERGLFDPEAAAGESVFDHHIYVIASDGDIE
EGVTSEASSLAGTQQLGNLTVIYDANEISIEDDTRIALSEDTAKRYEAYGWQVLTVHGGEDVTGLLEAIETAKAETSRPT
LIVLRTVIGYPAPTKMNTGKAHGAALGAEEVAGVKQALGFDPEQSFEVAPEVLEHARKVAERGKAAHEKWQVEFEAWAQA
NPERKALLDRLSKRELPAGWQEKLPTYEVGGKAVATRKASGEVLAALADVLPELWGGSADLAESNNTTMKGVESFGPAEI
STGTWTAQPYGRTLHFGIREHAMGSILNGIALHGGTRPYGGTFLIFSDYMRPAVRLAALMKTPVVYVWTHDSIGLGEDGP
THQPIEQLASLRAIPGLSVVRPADANETAAAWKAILEDTSGPAGLALTRQGVPTLEGTDAEGVARGGYVLAEAGSGEPDL
VIIATGSEVELAVAARKTLEADGVATRVVSMPCVEWFDAQDEAYREQVLPRGVRARVVVEAGIAQPWYRFAKDSGEIVSI
EHFGASADYKTLFKEFGFTADAVVAAARRSLDNARANA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-123 46
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-125 46