Gene Information

Name : serS (SACE_0158)
Accession : YP_001102436.1
Strain : Saccharopolyspora erythraea NRRL 2338
Genome accession: NC_009142
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 184811 - 185998 bp
Length : 1188 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
GTGGTGGACGCGCTGCTGTCCGCCGACGAGCGTCGCAGGTCAGCGGTGTCCCGCGCGGACTCGCTGCGCGCCGAGCAGAA
GCAGCTCGGCAAGCAGGTCGGCAAGGCCGCCGGCGAGGAGCGCGAGCACCTGCTCAAGAAGGCCAAGGAGCTCTCGGCCC
AGGTCAAGGACGCCGAGGCCGAGCAGGCCGAGGCCGACCAGGCGCTGGTCGAGGCGCAGAAGAAGCTCTCCAACATCGTC
GGGCCGGGGGTCCCCCCGGGCGGTGAGGACGACTACGCCGTGCTCAAGCACGTCGGCGTTCCCCCCGAGTTCGACTTCGA
GGTCAAGGACCACCTCGAGCTCGGCACGTCGCTGGGCGCGATGGACATGGAGCGCGGGGCGAAGGTCGCCGGCGCGCGGT
TCTACTTCCTCACCGGCATCGGCGCGCAGCTCGAGCTGGCGCTGCTGAACATGGCCGCGGCGCACGCCACCGCCAACGGG
TTCACGCTGGTCGTGCCGCCGGTGCTGGTGCGCCCGGAGATCATGGAGGGCACCGGCTTCCTGGGCGCGCACTCCTCCGA
GGTCTACCGGCTGGAGGAGGACGACCTCTACCTGGTCGGCACCTCCGAGGTCCCGCTGGCGGGCTACCACTCGGGCGAGA
TCATCGACCTCGGCGCCGGTCCGCTGCGCTACGCGGGCTGGTCGTCGTGCTTCCGCCGCGAGGCGGGCTCCTACGGCCGC
GACACCCGCGGCATCATCCGCGTGCACCAGTTCAACAAGCTGGAGATGTTCGTGTACTGCCGCGAGGAGGACGCGGTGGC
CGAGCACGAGCGGCTGCTGGGCTGGGAGGAGGAGATGCTGGCCAAGATCGAGGTGCCCTACCGGGTGATCGACACCGCGG
CCGGCGACCTCGGTGCCAGCGCGGCCCGCAAGTACGACTGCGAGGCGTGGATCCCCAGCCAGCAGACCTACCGCGAGCTG
ACCTCCACCTCGAACTGCACCACGTTCCAGGCGCGGCGGCTCAACACCCGCTACCGGGAGGCCGACGGCCCGACCCGGAT
CGCGGCCACCCTCAACGGCACGCTGGCCACCACCCGCTGGATCGTGGCGATCCTGGAGAACCACCAGCAGGCCGACGGCT
CGGTGCGGGTGCCGGAGGCGCTGCGGCCGTTCCTGGGCGGGCGCGAGGTGCTCGAACCTACGCGCTGA

Protein sequence :
MVDALLSADERRRSAVSRADSLRAEQKQLGKQVGKAAGEEREHLLKKAKELSAQVKDAEAEQAEADQALVEAQKKLSNIV
GPGVPPGGEDDYAVLKHVGVPPEFDFEVKDHLELGTSLGAMDMERGAKVAGARFYFLTGIGAQLELALLNMAAAHATANG
FTLVVPPVLVRPEIMEGTGFLGAHSSEVYRLEEDDLYLVGTSEVPLAGYHSGEIIDLGAGPLRYAGWSSCFRREAGSYGR
DTRGIIRVHQFNKLEMFVYCREEDAVAEHERLLGWEEEMLAKIEVPYRVIDTAAGDLGASAARKYDCEAWIPSQQTYREL
TSTSNCTTFQARRLNTRYREADGPTRIAATLNGTLATTRWIVAILENHQQADGSVRVPEALRPFLGGREVLEPTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-59 44