Gene Information

Name : floR (SNSL254_pSN254_0040)
Accession : YP_001101919.1
Strain :
Genome accession: NC_009140
Putative virulence/resistance : Resistance
Product : florfenicol/chloramphenicol resistance protein FloR
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 25530 - 26744 bp
Length : 1215 bp
Strand : +
Note : identified by similarity to GB:CAD57670.1; match to protein family HMM PF07690; match to protein family HMM TIGR00710

DNA sequence :
ATGACCACCACACGCCCCGCGTGGGCCTATACGCTGCCGGCAGCACTGCTGCTGATGGCTCCTTTCGACATCCTCGCTTC
ACTGGCGATGGATATTTATCTCCCTGTCGTTCCAGCGATGCCCGGCATCCTGAACACGACGCCCGCTATGATCCAACTCA
CGTTGAGCCTCTATATGGTGATGCTCGGCGTGGGCCAGGTGATTTTTGGTCCGCTCTCAGACAGAATCGGGCGACGGCCA
ATTCTACTTGCGGGCGCAACGGCTTTCGTCATTGCGTCTCTGGGAGCAGCTTGGTCTTCAACTGCACCGGCCTTTGTCGC
TTTCCGTCTACTTCAAGCAGTGGGCGCGTCGGCCATGCTGGTGGCGACGTTCGCGACGGTTCGCGACGTTTATGCCAACC
GTCCTGAGGGTGTCGTCATCTACGGCCTTTTCAGTTCGGTGCTGGCGTTCGTGCCTGCGCTCGGCCCTATCGCCGGAGCA
TTGATCGGCGAGTTCTTGGGATGGCAGGCGATATTCATTACTTTGGCTATACTGGCGATGCTCGCACTCCTAAATGCGGG
TTTCAGGTGGCACGAAACCCGCCCTCTGGATCAAGTCAAGACGCGCCGATCTGTCTTGCCGATCTTCGCGAGTCCGGCTT
TTTGGGTTTACACTGTCGGCTTTAGCGCCGGTATGGGCACCTTCTTCGTCTTCTTCTCGACGGCTCCCCGTGTGCTCATA
GGCCAAGCGGAATATTCCGAGATCGGATTCAGCTTTGCCTTCGCCACTGTCGCGCTTGTAATGATCGTGACAACCCGTTT
CGCGAAGTCCTTTGTCGCCAGATGGGGCATCGCAGGATGCGTGGCGCGTGGGATGGCGTTGCTTGTTTGCGGAGCGGTCC
TGTTGGGGATCGGCGAACTTTACGGCTCGCCGTCATTCCTCACCTTCATCCTACCGATGTGGGTTGTCGCGGTCGGTATT
GTCTTCACGGTGTCCGTTACCGCGAACGGCGCTTTGGCAGAGTTCGACGACATCGCGGGATCAGCGGTCGCGTTCTACTT
CTGCGTTCAAAGCCTGATAGTCAGCATTGTCGGGACATTGGCGGTGGCACTTTTAAACGGTGACACAGCGTGGCCCGTGA
TCTGTTACGCCACGGCGATGGCGGTACTGGTTTCGTTGGGGCTGGTGCTCCTTCGGCTCCGTGGGGCTGCCACCGAGAAG
TCGCCAGTCGTCTAA

Protein sequence :
MTTTRPAWAYTLPAALLLMAPFDILASLAMDIYLPVVPAMPGILNTTPAMIQLTLSLYMVMLGVGQVIFGPLSDRIGRRP
ILLAGATAFVIASLGAAWSSTAPAFVAFRLLQAVGASAMLVATFATVRDVYANRPEGVVIYGLFSSVLAFVPALGPIAGA
LIGEFLGWQAIFITLAILAMLALLNAGFRWHETRPLDQVKTRRSVLPIFASPAFWVYTVGFSAGMGTFFVFFSTAPRVLI
GQAEYSEIGFSFAFATVALVMIVTTRFAKSFVARWGIAGCVARGMALLVCGAVLLGIGELYGSPSFLTFILPMWVVAVGI
VFTVSVTANGALAEFDDIAGSAVAFYFCVQSLIVSIVGTLAVALLNGDTAWPVICYATAMAVLVSLGLVLLRLRGAATEK
SPVV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
flo AAK02049.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 7e-162 99
floRc AGK06972.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 7e-162 99
floRc AGK07102.1 chloramphenicol and florfenicol resistance protein Not tested SGI1 Protein 7e-162 99
floR YP_005176183.1 florfenicol / chloramphenicol efflux protein Not tested ICEPmu1 Protein 2e-161 99
cmlA9 ABZ01840.1 CmlA9 chloramphenicol efflux protein Not tested SGI2 Protein 3e-149 92
cmlA CAJ77032.1 chloramphenicol and florfenicol resistance protein Not tested AbaR1 Protein 3e-149 92
cml(A)5 ACY75522.1 CmLA(5) Not tested Tn6060 Protein 1e-81 50
cmlA5 CAJ77046.1 Chloramphenicol resistance protein Not tested AbaR1 Protein 3e-81 50

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
floR YP_001101919.1 florfenicol/chloramphenicol resistance protein FloR DQ522237.1.gene4.p01 Protein 9e-82 50
floR YP_001101919.1 florfenicol/chloramphenicol resistance protein FloR NC_010410.6003586.p0 Protein 9e-82 50
floR YP_001101919.1 florfenicol/chloramphenicol resistance protein FloR DQ984668.gene.p01 Protein 9e-82 50
floR YP_001101919.1 florfenicol/chloramphenicol resistance protein FloR AF156486.gene.p01 Protein 2e-80 49
floR YP_001101919.1 florfenicol/chloramphenicol resistance protein FloR AF294653.1.gene4.p01 Protein 3e-81 49