Gene Information

Name : merB (SNSL254_pSN254_0164)
Accession : YP_001102036.1
Strain :
Genome accession: NC_009140
Putative virulence/resistance : Resistance
Product : alkylmercury lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.99.1.2
Position : 144704 - 145342 bp
Length : 639 bp
Strand : -
Note : cleaves the carbon-mercury bond of organomercuric compounds

DNA sequence : 
ATGAAGCTCGCCCCATATATTTTAGAACGTCTCACTTCGGTCAATCGTACCAATGGTACTGCGGATCTCTTGGTCCCGCT
ACTGCGGGAACTCGCCAAGGGGCGTCCGGTTTCACGAACGACACTTGCCGGGATTCTCGACTGGCCCGCTGAGCGAGTGG
CCGCCGTACTCGAACAGGCCACCAGTACCGAATATGACAAAGATGGGAACATCATCGGCTACGGCCTCACCTTGCGCGAG
ACTTCGTATGTCTTTGAAATTGACGACCGCCGTCTGTATGCCTGGTGCGCGCTGGACACCTTGATATTTCCGGCGCTGAT
CGGCCGTACAGCTCGCGTCTCATCGCATTGCGCTGCAACCGGAGCACCCGTTTCACTCACGGTTTCACCCAGCGAGATAC
AGGCTGTCGAACCTGCCGGCATGGCGGTGTCCTTGGTATTGCCGCAGGAAGCAGCCGACGTTCGTCAGTCCTTCTGTTGC
CATGTACATTTCTTTGCATCTGTCCCGACGGCGGAAGACTGGGCCTCCAAGCATCAAGGATTGGAAGGATTGGCGATCGT
CAGTGTCCACGAGGCTTTCGGCTTGGGCCAGGAGTTTAATCGACATCTGTTGCAGACCATGTCATCTAGGACACCGTGA

Protein sequence : 
MKLAPYILERLTSVNRTNGTADLLVPLLRELAKGRPVSRTTLAGILDWPAERVAAVLEQATSTEYDKDGNIIGYGLTLRE
TSYVFEIDDRRLYAWCALDTLIFPALIGRTARVSSHCAATGAPVSLTVSPSEIQAVEPAGMAVSLVLPQEAADVRQSFCC
HVHFFASVPTAEDWASKHQGLEGLAIVSVHEAFGLGQEFNRHLLQTMSSRTP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0086 NP_763641.1 alkylmercury lyase Not tested SCCpbp4 Protein 2e-37 47
merB BAB47641.1 organomercurial lyase Not tested Type-III SCCmec Protein 5e-37 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
merB YP_001102036.1 alkylmercury lyase BAC0659 Protein 1e-96 100
merB YP_001102036.1 alkylmercury lyase BAC0657 Protein 9e-55 59
merB YP_001102036.1 alkylmercury lyase BAC0658 Protein 3e-37 47
merB YP_001102036.1 alkylmercury lyase BAC0663 Protein 2e-36 43
merB YP_001102036.1 alkylmercury lyase BAC0654 Protein 2e-36 43