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Name : HEAR1542 (HEAR1542) Accession : YP_001099834.1 Strain : Herminiimonas arsenicoxydans Genome accession: NC_009138 Putative virulence/resistance : Resistance Product : toxic metal efflux pump Function : - COG functional category : P : Inorganic ion transport and metabolism COG ID : COG2217 EC number : 3.6.3.3 Position : 1531700 - 1534081 bp Length : 2382 bp Strand : + Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Product type pt : transporter DNA sequence : ATGAGCAACTGCTGCTCCAAAGAATGCAGCGTTACCAGCAACGCTGTCGATGTAGAAAATAACGACACCGAACTCAAAGG TACACAGACGCTGTTTCGCATCGAGAATATGGACTGCCCAACTGAAGAGGGCTTAATTCGAAACAGTTTGCAAAAGATTG AAGGGGTCACCGCTCTCGATTTCAACCTTATGCAACGCAAACTTACAGTCACTCATGCACTGACATCTACCGCACCGTTG GTGGCGGCGTTGTCGTCAATCGGCATGCAGGCGCAAGAACTGAGCGCTCGCCGCACGACACTGCTCATCTCCAAGATGGA TTGTCCAACCGAAGAGGGATTGATCCGCAAGAAACTGCATGGCATGGCGAGCATTGAGGACCTGCAGTTCAACTTGATGC AGCGCACCCTGACATTCACTCATGCGCCTGAAGCGTTGGCACCAGTGCTGGTGGCATTGCAGGAAATTGGCCTTGGGGCA GAAACTCAGGAAAGCACTCAAGACGGCGCAAAATCCCAGCCTACATCGAATGCTTCATGGCTACCGCTGGCGCTTTCCGG CATCACCGCATTATCTGCAGAGGTCGTGCATTGGTACAACGGTGGCAATAATTGGATGGTAATCACGCTCGCACTGGGGG CAATCCTATTAGGCGGACTGGATACATACAAGAAAGGTTGGATTGCGGTGCGGCATGGCAATCTCAACATGAATGCCTTG ATGACAATCGCCGTGACCGGTGCTCTCGCAATCGGACAGTGGCCTGAAGCTGCGATGGTCATGTTCTTGTTTGCGCTGGC AGAGTTGATTGAACAGAAATCACTGGACCGTGCGCGTAACGCGATTCGTGGGCTGATGGATATGACGCCGGAAACTGCGA CAGTGCGACAGGCGGACGGCTCTTGGGCAGACATAGAGGCCAAGACGATTGCACTCGGCGCAATAATTCGGGTTCGCCCT GGTGAGCGCATTGCTCTGGACGGTAAGCTAATTAATGGGCAGTCAACAATTAACCAAGCGCCTATTACCGGTGAAAGCGT GCCGGTTGAAAAAAGCATTGGCGATACAGTGTTTGCCGGAACAATCAATGACGCGGGTTCTTTTGAATTTGAAGTCACCG CTCGGTCTGAAAGCACGACCTTAGCGCGGATCATTCATGCCGTCGAAGAAGCCCAAGGTAGTCGCGCACCGACTCAACGT TTTGTCGATCAGTTCGCCAAGATTTATACACCGGCAGTGTTCGTTGTTGCAGTCTTGGTTGCATTGGTGCCACCGCTGGC GTTTGGGCAGCCTTGGTATGACTGGATCTATAAGGCATTAGTCTTATTGGTAGTTGCCTGTCCATGCGCGCTGGTCATAT CGACACCGGTTACGATTGTCAGCGGCCTCGCGGCGGCGGCACGCAAGGGCATACTAATCAAGGGTGGCGTGTATCTGGAA CAAGGGCGCAAGCTCAGTTGGTTGGCGTTGGATAAAACGGGCACTCTCACCCTCGGCAAGCCAAGCGTTACCGATTATCT GCCGAGTGCCGTTTCTCAATCAAACACCCTTGAAATCGCCACCAGCCTTGCGGGACGTTCCGATCACCCAGTCTCTCGCG CGATTTCGGTGTATGGCGATGCGCATATAACAGCGCGTAATGAAGTCGACAACTTCCGCGCCTTGCTCGGACGTGGTGTT GAAGGACATATCCACGGCCAGCTATATTGGCTGGGCAACCATAGACTAGCAACCGAGCGCGAACAGATTACGCCAGAGCT GGCGGGTCAATTGGAAGCGCTGGAACGCCAAGGACGCACGGCGGTTATGTTGGGATCTGCGGAGCACGTCCTGGCGATCT TTGGTGTGGCCGACACTCTGCGTGAAACCAGTCGGCAGGCGATTGCGGAATTACATGAACTGAACGTGAAGACGGTGATG CTGACCGGCGATAACGTGCATACCGCACAAGCCATTGCTACCGAAGTAGGAATTGACGATGCACGGGGCAACCAACTTCC GGAAGACAAACTACAGGTCATTGAAGCTCTTGCGGCACAAGGCGCGACTATTGGCATGGTTGGCGACGGCATCAACGATG CACCTGCACTAGCGAAGGCTCATATTGGTTTCGCAATGGGTGCGGCTGGCACCGACACTGCTATTGAAACAGCTGACGTG GCCCTGATGGATGATGATCTGCGCAAAGTACCAGCGTTCGTGCGTCTCTCGCGCAGTACTGCTGCCATCCTTACCCAAAA CATCGTACTGGCACTCGGGATTAAAGCGGTGTTCTTGGTGCTGACCTTTACCGGTCAAGCGACCATGTGGATGGCCGTTT TTGCAGATATGGGAGCCAGTTTGCTTGTGGTGTTTAACGGTTTGCGCTTATTGCGAAAATGA Protein sequence : MSNCCSKECSVTSNAVDVENNDTELKGTQTLFRIENMDCPTEEGLIRNSLQKIEGVTALDFNLMQRKLTVTHALTSTAPL VAALSSIGMQAQELSARRTTLLISKMDCPTEEGLIRKKLHGMASIEDLQFNLMQRTLTFTHAPEALAPVLVALQEIGLGA ETQESTQDGAKSQPTSNASWLPLALSGITALSAEVVHWYNGGNNWMVITLALGAILLGGLDTYKKGWIAVRHGNLNMNAL MTIAVTGALAIGQWPEAAMVMFLFALAELIEQKSLDRARNAIRGLMDMTPETATVRQADGSWADIEAKTIALGAIIRVRP GERIALDGKLINGQSTINQAPITGESVPVEKSIGDTVFAGTINDAGSFEFEVTARSESTTLARIIHAVEEAQGSRAPTQR FVDQFAKIYTPAVFVVAVLVALVPPLAFGQPWYDWIYKALVLLVVACPCALVISTPVTIVSGLAAAARKGILIKGGVYLE QGRKLSWLALDKTGTLTLGKPSVTDYLPSAVSQSNTLEIATSLAGRSDHPVSRAISVYGDAHITARNEVDNFRALLGRGV EGHIHGQLYWLGNHRLATEREQITPELAGQLEALERQGRTAVMLGSAEHVLAIFGVADTLRETSRQAIAELHELNVKTVM LTGDNVHTAQAIATEVGIDDARGNQLPEDKLQVIEALAAQGATIGMVGDGINDAPALAKAHIGFAMGAAGTDTAIETADV ALMDDDLRKVPAFVRLSRSTAAILTQNIVLALGIKAVFLVLTFTGQATMWMAVFADMGASLLVVFNGLRLLRK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ORF C97 | AAN62190.1 | putative metal-transporting P-type ATPase | Not tested | PAGI-2(C) | Protein | 0.0 | 68 |
| unnamed | BAB47609.1 | cadmium resistance protein B | Not tested | Type-III SCCmec | Protein | 2e-115 | 50 |
| cadA | BAC57487.1 | Probable cadmium-transporting ATPase (Cadmium efflux ATPase) | Not tested | Type-IIIinv SCCmec | Protein | 2e-115 | 50 |
| SE0075 | NP_763630.1 | cadmium resistance protein B | Not tested | SCCpbp4 | Protein | 2e-114 | 49 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| HEAR1542 | YP_001099834.1 | toxic metal efflux pump | BAC0298 | Protein | 0.0 | 65 |
| HEAR1542 | YP_001099834.1 | toxic metal efflux pump | BAC0461 | Protein | 2e-83 | 43 |
| HEAR1542 | YP_001099834.1 | toxic metal efflux pump | BAC0455 | Protein | 7e-78 | 41 |
| HEAR1542 | YP_001099834.1 | toxic metal efflux pump | BAC0124 | Protein | 1e-74 | 41 |
