Gene Information

Name : Shew_0466 (Shew_0466)
Accession : YP_001092597.1
Strain : Shewanella loihica PV-4
Genome accession: NC_009092
Putative virulence/resistance : Resistance
Product : acriflavin resistance protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0841
EC number : -
Position : 521519 - 524593 bp
Length : 3075 bp
Strand : -
Note : PFAM: acriflavin resistance protein; KEGG: shm:Shewmr7_0550 acriflavin resistance protein

DNA sequence :
ATGAATTTTGCCGAGTATTCGATCACCCACAAGGTGGTCAGTTGGATGTTTGCCCTGCTGCTCCTCATAGGTGGCAGCCT
GTCGTTCATGAGCCTGGGGCAGCTGGAATTTCCCGAATTTACCATTAAAGAGGCACTGGTCGTCACCGCCTACCCTGGCG
CTTCGCCGGAGCAGGTGGAGGAAGAGGTTACCCTGCCCCTGGAAGATGCGCTGCAGCAGCTCGATGGGGTGAAACATATC
ACCTCGATCAACAGCGCCGGCCTGTCGCAGATCCAGATTGAGATGGAGGACAAGTACGACGCCGAGAAGCTGCCGCAGAT
CTGGGATCTGGTGCGCCGTAAGGTAAGCGATACCCAGGGGAGTCTGCCCAGCGGCGCCATGACACCTCAGGTGATCGACG
ACTTCGGCGACGTCTATGGCATTCTGCTCAACCTCAGCGGCGACGGCTACAGCGAACGCGAGCTGGAAAACTATGCCGAC
TTTCTGCGCCGCGAGCTGGTGCTGGTCGATGGGATCAAGCGCGTCAACATCGCAGGTATCGTCGACCAACAGGTAGTAGT
GGAGATCTCCACTCAGAAGATCAACGCCTTAGGCCTGAACCAGGACTATATCTATGGCCTGATCAACAGCCAGAACGTGG
TCTCTAACGCGGGTAGCATTCGCGTGGGCGACAACCGTATCCGCATCCACCCCACGGGCGAGTTCGACAGCGTCGAGGCG
CTATCACGCCTTGTGGTGAGTGCGCCCGGTAGCGCCAAGCTGATCTACCTGGGGGATATCGCCAACATCTACAAGGCGAT
GGACGAGACCCCGAGCAACCTGTATCACAGCGGCGGCGACATGGCGCTGTCTGTGGGCATCGCCTTCTCCAGCGGCGTCA
ACGTGGTCAAGGTGGGCGAGGCGGTCAATCAGAAGATGATGGCGCTCAGCGACGAGCTGCCGGTGGGCATGATGCTGACC
ACAGTCTACGACCAGAGCAAGATGGTGGATCAGACCATCAACGGCTTTTTGGTGAACCTGGCGGAATCGATCGCCATCGT
TATCGGCGTGCTGCTGATCTTCATGGGGCTGAGATCTGGCCTGCTAATGGGGCTAGTGCTGCTGCTCACCATTCTCGGTA
CCTTCATCATGATGAAGGTGCTCAATATCGAGCTGCAGATCATCTCGCTGGGGGCATTGATCATCGCCCTGGGGATGTTG
GTGGATAACGCCATCGTGGTAACTGAAGGGATCATCATAGGCCTCAAGCGCGGCCAGTCGCGTCTGGAGACCGCCAAGCA
GGTGATCACTCAGACCCAGTGGCCACTGCTGGGGGCGACGGTTATTGCCATCATCGCCTTCGCGCCTATCGGTCTGTCGG
ACAACGCCACGGGTGAGTTTTGTATCTCTCTGTTCCTGGTGCTGCTGATCTCCCTGTTTATCAGCTGGATCACCGCCATG
ACGCTGACCCCCTTCTTCTGCGATCTGCTGTTTAAGGATGGCGAGATCCCCGATGAAGCAGATAGCGACCCCTACAAGGG
TTGGCTGTTCCAGCTCTATCGCGGCAGCCTGAGCCTGGCGATGCGTTTTCGCGGCCTGACCCTGCTGGTCGTGCTGCTGG
CCCTGGTGGGTTCGGTGATGGGCTTTGGTCAGGTGAAAAACGTCTTCTTCCCGGCCTCTAACACCCCTATCTTCTTCGTG
GATGTGTGGATGCCTGAAGGCAGCGACATCAAGGCCACCGAGGCGCTGCTGGGTCGTATCGAGCAGGATTTAATGGCGGA
GCAGGAGAAACAGGATCTCGGCCTGGTGAACATCACCAGTGTGGTCGGCCAGGGCGCCCAGCGCTTCGTGCTGCCCTATG
TGCCGGAGAAGGGCTACGCCGCCTATGGCCAGCTGCTGATCGAGATGAGCAATCTGGAGACCCTCAATGCCTATATGCGC
AGGCTCGAGCAGGACCTGGTACAGCACTACCCAGAGGCGGAATATCGCTTCAAGTATATGGAGAATGGCCCCAGCCCGGC
GGCCAAGATCGAGGCACGCTTCTACGGCGAAGACCCAGAGGTGCTGAGACAGCTGGCCCAGCAGGCGAGCGAGATCTTCC
TCGCCGAGCCGAGCGCCACCAGCGTGCGCCACAACTGGCGTAACCAGGTAACCCTGGTGCGTCCACAGCTGGCACTGGCT
CAGGCCAGGGAAACCGGCATCAGTAAGCAAGATCTGGATAACGCCCTGCTGACCAACTTCAGCGGCAAGCATGTCGGCCT
GTATCGTGAGAACAGCCATCTGCTACCAATTATTGCCCGGGCGCCGGCCGATGAACGTCTCAATGCCGACAGCATCTCGG
CGCTGCAGGTGTGGAGCACGGAAAACAATGTGTTCGTGCCCATCTCTCAGGTGGTCAGTGACTTCACCACAGAGTGGGAA
GATCCGCTGATCATGCGCCGCGACCGTAAGCGGGTGATCTCTGTGCTCGCCGACCCGTTGAACGGCGGCAACGAGACCGC
TGACTCGGTATTTAGAAAACTGCGACCTAAGGTCGAGGCCATCAGCCTACCCGCCGGCTATGAGCTGGAATGGGGCGGCG
AATATGAGACCTCAAGCGAGGCGCAGCAATCGGTATTTAGCTCGATCCCACTTGGCTACCTGGCGATGTTCCTGATAACC
GTGCTGCTGTTTAACTCGGTCAGACAGCCCCTGGTGATCTGGTTTACCGTGCCGCTGGCGCTGATCGGCGTGGTCTCAGG
CCTGCTGCTGTTCGATGCCCCCTTCAGCTTCATGGCGCTGCTGGGTCTGCTGAGTCTGACCGGGATGATCATCAAGAACG
GTATCGTCCTGGTGGATCAGATAAACCTCGAGCTGAGTCAGGGTAAGGATGCCTACCGCGCGGTATTCGACTCCTCGGTG
AGCCGTGTGCGTCCGGTGTTGATGGCGGCGATCACCACAATGCTGGGGATGATCCCCCTGCTGCCGGATGCCTTCTTCGG
CTCCATGGCGATCACCATCATCTTCGGCCTTGGCTTCGCCTCTGTGCTCACCCTGGTGGTGCTGCCGGTGGCCTACACCC
TGGTCTTCGGCATCAAGGTGCCTAAGACCGCATAA

Protein sequence :
MNFAEYSITHKVVSWMFALLLLIGGSLSFMSLGQLEFPEFTIKEALVVTAYPGASPEQVEEEVTLPLEDALQQLDGVKHI
TSINSAGLSQIQIEMEDKYDAEKLPQIWDLVRRKVSDTQGSLPSGAMTPQVIDDFGDVYGILLNLSGDGYSERELENYAD
FLRRELVLVDGIKRVNIAGIVDQQVVVEISTQKINALGLNQDYIYGLINSQNVVSNAGSIRVGDNRIRIHPTGEFDSVEA
LSRLVVSAPGSAKLIYLGDIANIYKAMDETPSNLYHSGGDMALSVGIAFSSGVNVVKVGEAVNQKMMALSDELPVGMMLT
TVYDQSKMVDQTINGFLVNLAESIAIVIGVLLIFMGLRSGLLMGLVLLLTILGTFIMMKVLNIELQIISLGALIIALGML
VDNAIVVTEGIIIGLKRGQSRLETAKQVITQTQWPLLGATVIAIIAFAPIGLSDNATGEFCISLFLVLLISLFISWITAM
TLTPFFCDLLFKDGEIPDEADSDPYKGWLFQLYRGSLSLAMRFRGLTLLVVLLALVGSVMGFGQVKNVFFPASNTPIFFV
DVWMPEGSDIKATEALLGRIEQDLMAEQEKQDLGLVNITSVVGQGAQRFVLPYVPEKGYAAYGQLLIEMSNLETLNAYMR
RLEQDLVQHYPEAEYRFKYMENGPSPAAKIEARFYGEDPEVLRQLAQQASEIFLAEPSATSVRHNWRNQVTLVRPQLALA
QARETGISKQDLDNALLTNFSGKHVGLYRENSHLLPIIARAPADERLNADSISALQVWSTENNVFVPISQVVSDFTTEWE
DPLIMRRDRKRVISVLADPLNGGNETADSVFRKLRPKVEAISLPAGYELEWGGEYETSSEAQQSVFSSIPLGYLAMFLIT
VLLFNSVRQPLVIWFTVPLALIGVVSGLLLFDAPFSFMALLGLLSLTGMIIKNGIVLVDQINLELSQGKDAYRAVFDSSV
SRVRPVLMAAITTMLGMIPLLPDAFFGSMAITIIFGLGFASVLTLVVLPVAYTLVFGIKVPKTA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1355 YP_001217299.1 AcrB/AcrD/AcrF family transporter Not tested VPI-2 Protein 1e-176 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shew_0466 YP_001092597.1 acriflavin resistance protein BAC0519 Protein 0.0 55
Shew_0466 YP_001092597.1 acriflavin resistance protein BAC0428 Protein 0.0 54
Shew_0466 YP_001092597.1 acriflavin resistance protein BAC0526 Protein 0.0 52
Shew_0466 YP_001092597.1 acriflavin resistance protein BAC0425 Protein 5e-177 41