Gene Information

Name : alr (Shew_3277)
Accession : YP_001095402.1
Strain : Shewanella loihica PV-4
Genome accession: NC_009092
Putative virulence/resistance : Unknown
Product : alanine racemase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0787
EC number : 5.1.1.1
Position : 3920029 - 3921105 bp
Length : 1077 bp
Strand : -
Note : converts L-alanine to D-alanine which is used in cell wall biosynthesis; binds one pyridoxal phosphate per monomer; forms a homodimer

DNA sequence :
TTGAAACCCTTTCCCCGAGCAGAGATCAGCGGCGATGCGCTGAAAGCTAACCTAAAGCGATTACGCCAGCTGGCACCCCA
GAGTAAGGTGATGGCCGTGGTGAAGGCCAACGGCTATGGTCACGGCCTGTTGAATGTGGCCCATTGTCTGGCCAGCGCCG
ACGGTTTCGGCCTGGCGCGCCTCGAAGAGGCACTGGAGCTCAGGGCCGGTGGTGTGAGCGCCAAGCTGCTTCTGCTGGAA
GGCTTCTTTCGCCCAAGCGACGTGGCGACCCTAGTCGAGCATGATATCGATACCGTGGTGCACCACGAATCCCAGCTCGA
GATGCTGGAGGCCGCCAGCCTAGCCAAGCCGGTGACAGTGTGGATGAAGATAGATACCGGCATGCATCGTCTGGGCTTTA
ACCTGGATCAGTTTGAGGCTATCTATCAGCGTCTGCAGGCCTGTGCCAACGTGGCCAAGCCCATTAATCTGATGACACAT
TTTGCCTGCGCCGACGAGCCGGATAATCCGGCGACCGCCGAGCAGGCGCGCCGCTTCGAGCAGATGACGGCGAACTTGCC
GGGTGATCGCACCCTGGCCAACTCGGCCGCGACCCTCTACTGGCAGGCGACTCAGGCCGACTGGATCCGTCCGGGGATCG
CGCTTTATGGCGTTTCGCCTGTGGTTGGCGATCTCGGTCGCAATCATGGCCTGGAGCCCGCCATGGAGCTGGTGTCTCAG
CTGATTGCGGTACGGGATCATAAGGCCGGCGATCCCGTCGGCTATGGCAGCTACTGGCGCGCCAAGCAAGATACCAAGCT
AGGTGTGGTGGCCATAGGTTATGGCGACGGTTATCCCCGCAACGCCCCAGAAGGCACCCCTGTCTGGGTCAATGGCCGCC
TGGTACCCGTGGTGGGACGTGTCTCCATGGATATGCTGACGGTGGATCTCGGCCTGGATGCCACAGACAAGGTGGGCGAT
ACCGCCGTGCTCTGGGGCAAGGCGCTGCCGGTCGAAGAGGTGGCCGAGCATATCGGCACTATCGCCTATGAGCTGGTGAC
TAAGCTGACTCCCCGCGTCGCCGTCTGCCTCGAATGA

Protein sequence :
MKPFPRAEISGDALKANLKRLRQLAPQSKVMAVVKANGYGHGLLNVAHCLASADGFGLARLEEALELRAGGVSAKLLLLE
GFFRPSDVATLVEHDIDTVVHHESQLEMLEAASLAKPVTVWMKIDTGMHRLGFNLDQFEAIYQRLQACANVAKPINLMTH
FACADEPDNPATAEQARRFEQMTANLPGDRTLANSAATLYWQATQADWIRPGIALYGVSPVVGDLGRNHGLEPAMELVSQ
LIAVRDHKAGDPVGYGSYWRAKQDTKLGVVAIGYGDGYPRNAPEGTPVWVNGRLVPVVGRVSMDMLTVDLGLDATDKVGD
TAVLWGKALPVEEVAEHIGTIAYELVTKLTPRVAVCLE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
dadX AAC61705.1 alanine racemase Not tested PAI I CFT073 Protein 4e-56 45