Gene Information

Name : hemC (Shew_0318)
Accession : YP_001092449.1
Strain : Shewanella loihica PV-4
Genome accession: NC_009092
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 363663 - 364616 bp
Length : 954 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGGCCTCTGATGGAATATCGAGCATGTCTCAAAACGTCATTCGTATCGCTACACGTAAAAGTCCACTGGCAATGTGGCA
AGCTGAATTTGTTAAAGCCGAACTAGAAAAAGCCCATGAGGGTTTAGTCGTCGAACTGCTGCCGATGAGCACCAAGGGAG
ATGTCATCCTAGACACGCCATTGGCAAAGGTAGGTGGTAAAGGCTTGTTCGTTAAAGAGTTGGAAGTTGCCATGCTAGAA
GGCAAGGCAGATATCGCCGTGCACTCGATGAAAGATGTGCCGGTCGACTTCCCCGAAGGTTTGGGCCTGCAGGTGATCTG
CGAGCGTGAAGATCCACGCGATGCCTTCGTCTCAAATACCTATAAGAATATCGAAGAGTTACCACAGGGCGCCATCGTCG
GCACCTCGAGCCTGAGACGCCAATGCCAGATCCGTGCGGCGCGCCCAGATCTTGAGATCCGCGATCTGCGTGGCAACGTG
GGCACTCGCCTGGCCAAGCTAGATGCCGGCAACTATGACGCTATCATTCTGGCGGCCGCTGGCCTGAAACGCCTCAAACT
CGAAGACCGTATCGCCAGCTTTATCTCGGCGGAAGACTCGCTACCCGCTAACGGTCAAGGCGCCGTGGGTATCGAATGCC
GCACCGACGATGAACGCGTCAAGGCGCTACTTGCACCGCTAGAGCATATCGAAACCCGCTACCGCGTGATCGCCGAGCGT
GCCATGAACACTCGCCTGGAAGGTGGCTGTCAGGTGCCAATCGGTGCCTATGCGGAAATCGACGGCGACACCCTGTCGCT
TCGAGGCTTAGTAGGTAACCCAGACGGTAGCCAGGTGATCCGCGGCACAACCAGTGGCGCTAAGCAAGATGCTGAGCAGC
TGGGTATTGCACTGGCCGATGAGCTGCTATCTAAAGGCGCCAAAGCCATTTTAGATGCGGTATACGCCAAGTAA

Protein sequence :
MASDGISSMSQNVIRIATRKSPLAMWQAEFVKAELEKAHEGLVVELLPMSTKGDVILDTPLAKVGGKGLFVKELEVAMLE
GKADIAVHSMKDVPVDFPEGLGLQVICEREDPRDAFVSNTYKNIEELPQGAIVGTSSLRRQCQIRAARPDLEIRDLRGNV
GTRLAKLDAGNYDAIILAAAGLKRLKLEDRIASFISAEDSLPANGQGAVGIECRTDDERVKALLAPLEHIETRYRVIAER
AMNTRLEGGCQVPIGAYAEIDGDTLSLRGLVGNPDGSQVIRGTTSGAKQDAEQLGIALADELLSKGAKAILDAVYAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 2e-82 61
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 2e-82 61