Gene Information

Name : Shew_2491 (Shew_2491)
Accession : YP_001094616.1
Strain : Shewanella loihica PV-4
Genome accession: NC_009092
Putative virulence/resistance : Resistance
Product : methionine gamma-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.11
Position : 2930577 - 2931752 bp
Length : 1176 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: son:SO1812 methionine gamma-lyase

DNA sequence :
ATGCAAGATAAATGGAAACTTGCCACTCAGGTGATCCATGCTGGGCATGAGGCCAATCAGCATGGCGCCTTGGTATCCCC
TTTGGTGCAAAGCGCCACCTTTACCTTTGAGACAGTCGAGCAGGGCGGTGATTGCTTTGCCGGCGAACAACAAGGCTATA
TCTACACTCGCCTTGGCAATCCCACCACGGCAGAGCTAGAACGTAAGATGGCGGTGCTGGAAGGCAGTGAAGCCGCAGCC
GCGACCGCCTCCGGCATGGCGGCGGTATCTGCGGCCCTGCTGACCAATCTGAGCCAGGGCGACCACCTGGTCGCTTCCAA
GGCTGTCTATGGCTGTACCTTTGCCCTGATGACGGAGCAGTTTAAGCGCTTTGGCATAGAGGTGACCCTGGTGGATTTCT
GCGAGGTGGCCAACATAGCTCAGGCCATTCGCCCCAACACTAAGGCGCTGTTTTGCGAGACGCCTGTTAATCCACATCTG
GATGTCTATGATCTCGCCGCCATTGCTGCACTGGCCAAGCGCCATCAGCTGGTCAGTATCGTCGACAACACCTTTATGAC
GCCACTGTTGCAACGCCCGCTGAGCATGGGTATAGACATGGTGATCCACAGTGCGACTAAGTATCTCAACGGTCATGGTG
ACGTGATCGCCGGAATCGTCTGTGGCACCGAGGAGATGATCACTAAGGTCAAACTTGAGGTGCTCAAGGATATCGGCGGG
GTGATCTCGCCTCACGATGCCTGGCTGATCTTACGCGGGCTGAAGACGCTAGATGTCAGATTAGCGCGCCACTGCGACAA
CGCCGAGCGGGTCGCCGAATATCTGCAGCAGCACCCTCAGGTGGCCAGAGTCTATTATCCTGGCCTCAAGGGACATTCGG
GCCATGCCCTGCTGGGTAAGCAGATGCTCAGGGCCGGCGGTGTGGTCGCCTTCGAACTCAAAGGCAGCTTCGATGCCGCC
AAGGCGTTCGCTAATCGACTCAAGCTCTTTAAAATTGCGGTCAGTCTGGGGGATGCCGAGTCGTTGATCCAGCATCCTGC
CTCTATGACGCATTCCCCCTATTCGCCAGAGGCCAGAATGGACGCCGGCATAGGCGATAGCCTGTTGAGGATCTCCCTAG
GCCTGGAAGACAGCGATGACATCATTGCCGATCTGGCGCAGGCCTTCGGGGAATAG

Protein sequence :
MQDKWKLATQVIHAGHEANQHGALVSPLVQSATFTFETVEQGGDCFAGEQQGYIYTRLGNPTTAELERKMAVLEGSEAAA
ATASGMAAVSAALLTNLSQGDHLVASKAVYGCTFALMTEQFKRFGIEVTLVDFCEVANIAQAIRPNTKALFCETPVNPHL
DVYDLAAIAALAKRHQLVSIVDNTFMTPLLQRPLSMGIDMVIHSATKYLNGHGDVIAGIVCGTEEMITKVKLEVLKDIGG
VISPHDAWLILRGLKTLDVRLARHCDNAERVAEYLQQHPQVARVYYPGLKGHSGHALLGKQMLRAGGVVAFELKGSFDAA
KAFANRLKLFKIAVSLGDAESLIQHPASMTHSPYSPEARMDAGIGDSLLRISLGLEDSDDIIADLAQAFGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-61 42
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-60 41
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-56 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Shew_2491 YP_001094616.1 methionine gamma-lyase BAC0207 Protein 2e-84 50