Gene Information

Name : Shew_1856 (Shew_1856)
Accession : YP_001093981.1
Strain : Shewanella loihica PV-4
Genome accession: NC_009092
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2135122 - 2135859 bp
Length : 738 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAATGTGACTCTGTTAATCCCTGCTCGCTATGGCTCAAGCCGTTTTCCGGGTAAGCCATTGGCGCCGATTAACGGTAA
GCCGATGATCCAGCACGTTTACGAGCGTGCGGCGCTGGCAAAAGGCTTAACTGCCATCTATGTGGCCACCGACGATCTGC
GCATCAAGGAGGCCGTTGAAGCCTTTGGCGGTAAGGTAGTCATGACAGATGCCAATGCTGCCTCCGGCACCGACAGAATC
GAGGATGCAATCACCCAGCTTGGCTTGGCGGACGATGACCTGGTGATCAACCTCCAGGGCGATCAGCCGCTGATCGATCC
TATCTCCATCGAGCAGATCATCACACTGTTTGAGCGTCATCCAGGGGAGTTCGGCATGGCAACCCTAGGCTATGAGATCA
CCGAAGAGCATGAGCTTAACGATCCCAAGCACGTCAAGATGGTGTTCGACAACCAATTTAACGCCCTCTATTTCTCTCGT
GCCCGCATCCCCTTCGGCCGTGATACAGATGACTACCCGGTCTACAAACACCTGGGCGTGTATGCCTACACCCGCGAGTT
TGTCAGAACCTTCAATAAGCTGCCACTTGGCCGTTTAGAAGATCTCGAAAAGCTTGAGCAGCTGCGCGCACTGGAACATG
GCCACACGATCAAGGTTGCCATCAGCGCCTTCGACTCGCCCGAGGTCGATACCCCAGAAGATATTCGCATCTGCGAAGCA
CGCCTTGCGGTAGACTAG

Protein sequence :
MNVTLLIPARYGSSRFPGKPLAPINGKPMIQHVYERAALAKGLTAIYVATDDLRIKEAVEAFGGKVVMTDANAASGTDRI
EDAITQLGLADDDLVINLQGDQPLIDPISIEQIITLFERHPGEFGMATLGYEITEEHELNDPKHVKMVFDNQFNALYFSR
ARIPFGRDTDDYPVYKHLGVYAYTREFVRTFNKLPLGRLEDLEKLEQLRALEHGHTIKVAISAFDSPEVDTPEDIRICEA
RLAVD

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-42 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 9e-43 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 4e-43 45