Gene Information

Name : pykF (P9301_09471)
Accession : YP_001091171.1
Strain : Prochlorococcus marinus MIT 9301
Genome accession: NC_009091
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 815554 - 817344 bp
Length : 1791 bp
Strand : -
Note : catalyzes the formation of phosphoenolpyruvate from pyruvate

DNA sequence :
ATGTCGAATATTGATTTAAAAAGAAGAACAAAAATAGTAGCAACTATTGGCCCTGCAACTCAATCTGAAGAGATAATTAC
AAATTTAATTAAAGCTGGAGTAACAACATTCAGATTAAATTTCTCACATGGCGATCATAAAGATCATGCTGATAGAATAA
AAACCATAAGGGAAGTATCAAAAAAGTTAGATATAGATATTGGGATATTGCAAGATCTACAAGGACCTAAAATAAGATTA
GGGCGCTTTAAAGATGGGCCAGTAAAAGTTAAAAAAGGCGATAAATTCACACTTACATCAAATGAAGTCGAATGTACGAA
TACTATTGCAAATGTTACCTACGAAAAACTTTCTCAAGAAGTTAGCGAAGGAAAAAGAATACTTTTAGATGATGGAAAAA
TAGAAATGATTGTAGAAAAAGTTGATACAAAAGCTAATAATTTGGAGTGCATGGTAACTGTAGGAGGGGTTCTTTCAAAC
AATAAAGGTGTTAATTTTCCAGATGTTCAATTATCAGTAAAAGCATTAACAGAAAAAGATAAAAAGGATTTAAAATTTGG
ATTATCTGAAGGAGTTGATTGGATCGCACTAAGTTTTGTAAGAAATCCATCCGATATAAATGAGATAAAAGATTTAATAA
ATAAAAATGGTCATTCAACTCCTGTAGTCGCAAAAATAGAAAAATTTGAAGCAATCGATCAGATCGATACAGTATTACCC
TTATGTGATGGGGTTATGGTTGCAAGAGGTGATTTGGGAGTAGAAATGCCTGCCGAAGAAGTTCCTCTTTTACAAAAGGA
ATTAATAAGAAAAGCTAATTCATTAGGTATCCCAATAATTACAGCGACTCAAATGCTTGATTCAATGGCTTCTAACCCAA
GACCAACCAGGGCCGAAGTTAGTGATGTTGCAAATGCAATTCTGGATGGTACAGATGCAGTAATGCTTTCAAACGAAACT
GCAGTTGGCGATTATCCTGTGGAGGCAGTTGAAACGATGGCAACTATAGCAAGAAGAATTGAAAGGGATTATCCACTTAA
GGCTATTGAAAGCCACTTACCCAGTACGATCCCAAATGCTATTAGCGCAGCAGTAAGCAATATAGCTAGACAACTTGAAG
CAGGAGCTATAATCCCTTTAACTAAATCAGGTTCTACCGCTCGAAATGTAAGTAAGTTCAGACCACCAACACCCATCTTG
GCAACTACTACAGAAAGAAGTGTAGCGAGAAGATTGCAACTTGTTTGGGGAGTTACTCCAATAGTAGTTAAAAATGATGA
AAGAACAGCAAAAACTTTTAGTTTAGCTATGCAAATTGCTCAAGAGATGGGGATCCTTAATCAAGGAGATTTAGTAGTTC
AAACCGCAGGTACATTAACTGGAATTAGTGGCTCTACAGATTTAATAAAAGTCGGTTTAGTAAGAAGGATTGTATCAAGA
GGAATTTCAATAGGGGAAATCGGTGTTACAGGTAAAGCAAGAATAATTAAAAATAATCTTGATATATCTTTAATTTGCCC
AGGTGAAATATTATTTGTTCCGAAGGAATTAATGAAAAATATTCCACTGAGTAAAAATATTGCAGGCATTGTTACGAACC
AAAATGTAAATGATGTTTATGCTTTTTTTAACAAAAATAATAAAAAGATTTCTACAATTTGTAATTTAGAAAATATGGAT
AGTCATCAAATCAGTAATGGAGATCTCATTACTCTCCAGCTTAATGAAGGTGTCATATACATGGGCCAAATTGAAGATGA
TGATGCAATAGATAAATATAAATATGTCTAG

Protein sequence :
MSNIDLKRRTKIVATIGPATQSEEIITNLIKAGVTTFRLNFSHGDHKDHADRIKTIREVSKKLDIDIGILQDLQGPKIRL
GRFKDGPVKVKKGDKFTLTSNEVECTNTIANVTYEKLSQEVSEGKRILLDDGKIEMIVEKVDTKANNLECMVTVGGVLSN
NKGVNFPDVQLSVKALTEKDKKDLKFGLSEGVDWIALSFVRNPSDINEIKDLINKNGHSTPVVAKIEKFEAIDQIDTVLP
LCDGVMVARGDLGVEMPAEEVPLLQKELIRKANSLGIPIITATQMLDSMASNPRPTRAEVSDVANAILDGTDAVMLSNET
AVGDYPVEAVETMATIARRIERDYPLKAIESHLPSTIPNAISAAVSNIARQLEAGAIIPLTKSGSTARNVSKFRPPTPIL
ATTTERSVARRLQLVWGVTPIVVKNDERTAKTFSLAMQIAQEMGILNQGDLVVQTAGTLTGISGSTDLIKVGLVRRIVSR
GISIGEIGVTGKARIIKNNLDISLICPGEILFVPKELMKNIPLSKNIAGIVTNQNVNDVYAFFNKNNKKISTICNLENMD
SHQISNGDLITLQLNEGVIYMGQIEDDDAIDKYKYV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 45
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-76 45
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 7e-76 45
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-76 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pykF YP_001091171.1 pyruvate kinase VFG0479 Protein 7e-77 45