Gene Information

Name : lysS (P9301_18101)
Accession : YP_001092034.1
Strain : Prochlorococcus marinus MIT 9301
Genome accession: NC_009091
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1531823 - 1533361 bp
Length : 1539 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTCTGAAATAAAAGAAGCACGCTTACAAAAAGCTAGTTCACTCGTTAGTAAAGGTTTTGCTTCTTACGCGCAGAGTTT
TAGGGTATCACATACTACCAGTTTTCTTATTCAAAAATTTGATTATTTAGAAAATGGTCAAGAGGAAAACTTCAGTGTTT
CTCTGGCTGGTAGAGTAATGGCAAAAAGGGTAATGGGTAAAATTGCCTTTTTTACAATAAGCGATCAGGATGGCCAGATT
CAGCTTTATCTAGAAAAAAGGATTATTAATTTAAATTTAGAAAAACAAAAATTACTCTCTTTTGAAGATATCAAGGAAAT
AGTAGACATTGGTGATTGGATAGGCGTATACGGAACTATTAAAAAAACTAATAAAGGCGAGCTTTCAATTAAAGTAGAAA
AATGGGAAATGTTATCGAAATCATTACAACCATTGCCAGATAAATGGCATGGATTGACCGATATTGAAAAAAGATATAGA
CAACGTTATCTAGATTTAATAGTGAATCCTCACTCTAAAAATGTATTTAAAACAAGAGCAAAATGTATAAGTTTTATAAG
AAAATGGTTAGATAATAGAAATTTTTTAGAGATAGAGACTCCAATTCTGCAATCTGAAGCTGGTGGTGCCGAAGCAAGAC
CATTTATAACTCATCACAATACCTTAGATATTCCGCTTTATCTAAGAATAGCGACAGAATTACATTTAAAAAGAATGGTT
GTTGGAGGATTTGAGAAAGTATATGAATTAGGAAGAATCTTTCGTAATGAGGGGATAAGTACAAGACATAATCCTGAATT
CACCTCAGTTGAAATTTATGAAGCTTATTCTGATTATGTCGATATGATGAATTTAACTGAAGAATTGATTAAAGATATTC
TAGCTGATGCCTGTGGGTCTTTAACTATAAATTATCAAAATAAAGAAATTGATTTTTCAAAACCTTGGTTAAGAATATCC
ATGAAAGATATTGTCAAAAAATATACAGGGATTGATTTTCATTCTTTCAACGGAGACTTTCTAGCAGCAAAAAAAGCCGT
TAAAAATATAAATGTTGATTTCTCTAATAAAGTAAATACTATTGGAAGACTTTTAAATGAGGTCTTCGAGCAAAAAGTTG
AATCAAAACTTATAGAACCCACTTTTGTTATCGATTATCCTGTTGAAATTTCTCCTTTAGCTAGGCCTCATTTTGATAAT
AAAGAAATAGTTCAGAGATTTGAACTATTCATTGTTGGTCGAGAGCTGGCAAATGCGTTTAGTGAGTTAATAGATCCAGT
CGATCAAAGAGAAAGAATGCAATTACAGCAATCTCTTAGAGATAAAGGAGATCTGGAGGCTCACTGTATAGATGAAGATT
TCTTGAATGCTTTAGAGATTGGTATGCCGCCTACTGGAGGATTAGGCATAGGCATTGATAGATTAATTATGTTAATTACT
AACAGCGCATCGATTAGAGATGTAATCCCTTTCCCATTGTTAAAACCAGAAATATCTTCCAAAAAAAGTGAAAAATTACC
CTTGAATGAAGTAAAATAG

Protein sequence :
MSEIKEARLQKASSLVSKGFASYAQSFRVSHTTSFLIQKFDYLENGQEENFSVSLAGRVMAKRVMGKIAFFTISDQDGQI
QLYLEKRIINLNLEKQKLLSFEDIKEIVDIGDWIGVYGTIKKTNKGELSIKVEKWEMLSKSLQPLPDKWHGLTDIEKRYR
QRYLDLIVNPHSKNVFKTRAKCISFIRKWLDNRNFLEIETPILQSEAGGAEARPFITHHNTLDIPLYLRIATELHLKRMV
VGGFEKVYELGRIFRNEGISTRHNPEFTSVEIYEAYSDYVDMMNLTEELIKDILADACGSLTINYQNKEIDFSKPWLRIS
MKDIVKKYTGIDFHSFNGDFLAAKKAVKNINVDFSNKVNTIGRLLNEVFEQKVESKLIEPTFVIDYPVEISPLARPHFDN
KEIVQRFELFIVGRELANAFSELIDPVDQRERMQLQQSLRDKGDLEAHCIDEDFLNALEIGMPPTGGLGIGIDRLIMLIT
NSASIRDVIPFPLLKPEISSKKSEKLPLNEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 8e-100 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001092034.1 lysyl-tRNA synthetase VFG1668 Protein 5e-100 46