Gene Information

Name : clpC (CD630_00260)
Accession : YP_001086489.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : class III stress response-related ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 42914 - 45361 bp
Length : 2448 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12354604, 15529410, 16525504; Product type e : enzyme

DNA sequence :
GTGAACTTCAATAGATTTACACAAAGAGCTAAAAAGGCAATTGATTTAGCGTTTGAATCTGCTAAAAGTCTAGGACACAA
TATTGTCGGAAGTGAACATATACTTTTAGGTCTTTTAAGAGAAGAAGAAGGTATAGCTGCTAAAGTTCTAAGTAAAGTTG
GATTTACAGAAGCTTATTTAGAAGGCAAAATAGTTGATATGGAAGGTAAGGGAGAAGAAATCTCAGAAGATATAGTATTA
AGTCCAAGAAGTAAACAAATACTTGAATTATCAGGAATGTTTGCAAATAAATTAAAAACAAATTATATTGGGACTGAGCA
TATATTATTAGCAATTATTCAAGAAGGTGAAGGAATAGCTAATAAGATTTTAAATTATGCTGGAGTAAATGATAGGACTT
TAGCCCAATTAACAATTGATATGATGGGTATTAGTGATAAAAATCAATACAAAGCAGAAAATAGTTACACGGGCAACCAG
AATCAAGCAGAATCTAAAGTACTTGATAAGTATGGAAGAAATCTTACACTATATGCAAAACAGAATAAAATAGACCCTGT
AATAGGTAGAGAAAAAGAAATACAAAGAGTAATACAAATATTAAGTAGAAGAACTAAAAACAATCCAGTGTTGATAGGAG
ACCCAGGTGTAGGGAAAACAGCCATAGCTGAAGGTCTGGCTACAAATATAGCCTTAGGAAATGTTCCAGAAACACTAAAA
AACAAAACTTTATACTCTTTAGAGATGGGTTCATTATTGGCTGGAGCTAAGTATAGAGGAGAATTTGAAGAAAGAATTAA
AGAAGTTGTAGATGAAGTTGTTAAAAATGGAAACATAATCTTATTTATAGATGAGATGCACACAATAATAGGGGCTGGGT
CTACTGGAGAAGGCTCTATAGATGCTTCAAATATATTAAAGCCAGCCTTAGCAAGAGGAGAAATACAAGTTATAGGTGCA
ACTACAATTGATGAATATAGAAAGCATGTTGAAAAAGATTCTGCTCTAGAAAGAAGATTCCAACCAGTTATGGTAGATGA
ACCAACTAAAGAGGACTCAATAAAAATATTAGAAGGATTAAGAGATAAATATGAAGCTCATCATAAAGTTAAAATAACTG
ATGATGCTATAAAGGCAGCTGTAGAATTATCAACTAGATATATATCAGACAGATATCTGCCAGATAAAGCTATAGACTTG
ATTGATGAAGCTGCATCAAAAGTAAGATTAAAAGAAAATACACCTCCTTCAGAAATAAAAAAATTAGAACTAGAAATAGA
AAATATAGATAAAGAAAAAGAAGAAGCAGTAAGATGTCAAGACTTTGAGAAAGCAGCCAAAATAAGAGATGAACAAGGTC
TACTTAAAAAACAATTAGAAGATGTTAGAGAAAGATGGAACAAGTCATCTAAACATTCAGATTTAGTTGATGGAGAAGTT
ATTGCTGAAGTAGTGGGCTTATGGACAGGAATACCAGTTAATAAAATTCTTGAAGAAGAGGCTGATAGACTTTTGAGACT
TGAGGAAATACTGCACAATAGAGTTATAGGTCAAGAACAAGCAGTAAAATCTATTTCAAAGGCAATCAGAAGGTCAAGAG
CAGGTCTTAAAGACCCTAATAGACCAATTGGTTCATTTTTATTTTTAGGTCCAACAGGAGTAGGTAAAACAGAATTATCT
AAGGCATTAGCAGAAGTGCAATTTGGAGATGAAAATCAAATAATTAGAATAGATATGTCTGAATATATGGAAAAACATGC
TGTGTCAAGAATGATAGGTTCACCTCCAGGTTATGTAGGTCATGATGAAGGTGGTCAATTAACTGAAAAAGTAAGAAGAA
ATCCATATTCAGTTATCTTATTTGATGAGATAGAAAAAGCTCATCCAGATGTATTTAATATTCTGTTACAAATTCTAGAT
GATGGTAGACTAACTGATTCAAAAGGAAGAACTGTAGATTTTAAGAATACTATTGTAATAATGACATCAAATGTTGGAGC
ATCTACAATTGGTAGACAAAAAACTTTAGGATTTAGTATAGCTAAAGGAGACGAAGAAGAAAAATCTCAATATGAAAAAA
TGAAAGAAAATATAATGGGTGAATTAAAACAAAGATTCAGACCAGAGTTTTTAAACAGAATAGATGATATAATTGTTTTC
CACTCACTAAATGAAAATCATATATCAAAAATAGTACTTTTAATGGCAGCGAAACTACAAGAGAGATTAAAAGAAATGGA
TATAAAATTAGAAATGAGTGATGAGGCTGTTAAATTAATTTCTAAATCTGGATTTGACTTAGAATATGGAGCAAGACCTC
TTAAAAGAGCTTTACAAAAAGAGTTGGAAGATGAGCTATCTGAAGCAATCTTAAAAGGTAATGTGAAAAAGGGAAGTAAT
GTAGTAGCAAAAGTCAAAGATGAAAAAATAGTTTTTGAAACTAAATAA

Protein sequence :
MNFNRFTQRAKKAIDLAFESAKSLGHNIVGSEHILLGLLREEEGIAAKVLSKVGFTEAYLEGKIVDMEGKGEEISEDIVL
SPRSKQILELSGMFANKLKTNYIGTEHILLAIIQEGEGIANKILNYAGVNDRTLAQLTIDMMGISDKNQYKAENSYTGNQ
NQAESKVLDKYGRNLTLYAKQNKIDPVIGREKEIQRVIQILSRRTKNNPVLIGDPGVGKTAIAEGLATNIALGNVPETLK
NKTLYSLEMGSLLAGAKYRGEFEERIKEVVDEVVKNGNIILFIDEMHTIIGAGSTGEGSIDASNILKPALARGEIQVIGA
TTIDEYRKHVEKDSALERRFQPVMVDEPTKEDSIKILEGLRDKYEAHHKVKITDDAIKAAVELSTRYISDRYLPDKAIDL
IDEAASKVRLKENTPPSEIKKLELEIENIDKEKEEAVRCQDFEKAAKIRDEQGLLKKQLEDVRERWNKSSKHSDLVDGEV
IAEVVGLWTGIPVNKILEEEADRLLRLEEILHNRVIGQEQAVKSISKAIRRSRAGLKDPNRPIGSFLFLGPTGVGKTELS
KALAEVQFGDENQIIRIDMSEYMEKHAVSRMIGSPPGYVGHDEGGQLTEKVRRNPYSVILFDEIEKAHPDVFNILLQILD
DGRLTDSKGRTVDFKNTIVIMTSNVGASTIGRQKTLGFSIAKGDEEEKSQYEKMKENIMGELKQRFRPEFLNRIDDIIVF
HSLNENHISKIVLLMAAKLQERLKEMDIKLEMSDEAVKLISKSGFDLEYGARPLKRALQKELEDELSEAILKGNVKKGSN
VVAKVKDEKIVFETK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_001086489.1 class III stress response-related ATPase VFG0079 Protein 0.0 58
clpC YP_001086489.1 class III stress response-related ATPase VFG0080 Protein 7e-151 49