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Name : tetM (CD630_05080) Accession : YP_001086983.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Resistance Product : Tetracycline resistance protein Tn5397 Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0480 EC number : - Position : 600034 - 601953 bp Length : 1920 bp Strand : + Note : Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12568329,12568327,17650959, 11157942, 11073898, 8863741; Product type f : factor DNA sequence : ATGAAAATTATTAATATAGGTGTTTTAGCTCATGTTGACGCAGGAAAAACTACTTTGACAGAAAGCTTACTATATACTAG TGGAGCGATTGCGGAGTCAGGAAGCGTGGATACAGGCACAACAAGAACGGATACTACATTTTTAGAACGTCAGCGAGGAA TTACAATTCAGACAGCAGTAACCTCTTTTCAGTGGAAAGATATTAAGGTAAATATCATAGATACTCCAGGACATATGGAT TTTTTAGCAGAAGTATATCGCTCGTTATCAGTTTTAGATGGGGCAATCCTACTAATTTCTGCGAGAGATGGAGTACAAGC ACAAACTCGGATATTATTTCATGCACTAAATAAAATGGGTATTCCCACAATCTTTTTTATCAATAAGATTGACCAAAATG GGATTGATTTATCAACGGTTTATCAAGATATTAAAGAGAAACTTTCTATGGAAATTATAATCAAACAGAAAGTAGAGCTG CACCCTAATATGTGTGTGATGAGCTGTACGGAACCTGAGCAATGGGATGTGGTAATAGAAGGAAATGATTATCTTTTGGA GAAATATACACTTGGGAAATCATTGGAGATATTAGAACTCGAACAAGAGGAAATCAGAAGATTTCAGAATTGCTCCTTGT ACCCTGTTTATCATGGAAGCGCAAAAAGCAACATAGGGATTGAGCAGCTTATAGAAGTGATAACGAATAAATTTTATTCA TCAACATACAGAAAGAAGTCTGAACTTTGCGGAAATGTCTTCAAAATTGAATATTCGGAAGAAAGACAACGTCTTGCATA TGTACGCCTTTATGGCGGAATCCTGCATTTGCGGGATTCGGTTAGAATATCGGAAAAGGAAAAAATAAAAATTACAGAAA TGTATACTTCAATAAATGGTGAATTATGTAAAATTGATAAGGCTTATTCCGGGGAAATTGTTATTTTGCAAAATGAGTTT TTGAAGCTAAATAGTGTTCTTGGAGATACAAAGCTATTGCCACAGAGAGAGAGAATTGAAAATCCGCTCCCTCTGCTGCA AACAACTGTTGAACCGAGCAAACCTCAACAAAGGGAAATGTTACTTGATGCACTTTTAGAAATCTCCGACAGTGACCCGC TTCTACAATATTATGTGGATTCTACGACACATGAAATCATACTTTCTTTCTTAGGGAAAGTACAAATGGAAGTGACTTGT GCTCTATTGCAAGAAAAGTATCATGTGGAGGTAAAAATAAAAAAGCCTACAGTCATTTATATGGAAAGACCGTTAAAAAA AGCAGAGTATACCATTCACATCGAAGTGCCACCGAATCCCTTCTGGGCTTCCATTGGTCTTTCTGTAGCACCGCTTCCAT TAGGGAGCGGAGTACAGTATGAGAGCTCGGTTTCTCTTGGATACTTAAATCAATCGTTTCAAAATGCAGTTATGGAAGGG ATACGATATGGCTGTGAACAAGGATTGTATGGTTGGAATGTGACGGACTGTAAAATCTGTTTTAAGTATGGCTTATACTA TAGCCCTGTTAGTACCCCAGCAGATTTTCGGATGCTTGCTCCTATTGTATTGGAACAAGTTTTAAAAAAAGCTGGAACAG AATTGTTAGAGCCATATCTTAGTTTTAAAATTTATGCACCACAAGAATATCTTTCACGAGCATATAACGATGCTCCTAAA TATTGTGCGAACATCGTAGACACTCAACTGAAAAATAATGAGGTCATTCTTAGTGGAGAAATTCCTGCTCGGTGTATTCA AGAATATCGTAATGATTTAACTTTCTTTACAAATGGACGTAGCGTTTGTTTAACAGAGTTAAAAGGGTACTATGTTACTA CTGGTGAATCTGTTTGTCAGCCCCGTCGTCCAAATAGTCGGATAGATAAAGTACGATATATGTTCAATAAAATAACTTAG Protein sequence : MKIINIGVLAHVDAGKTTLTESLLYTSGAIAESGSVDTGTTRTDTTFLERQRGITIQTAVTSFQWKDIKVNIIDTPGHMD FLAEVYRSLSVLDGAILLISARDGVQAQTRILFHALNKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSMEIIIKQKVEL HPNMCVMSCTEPEQWDVVIEGNDYLLEKYTLGKSLEILELEQEEIRRFQNCSLYPVYHGSAKSNIGIEQLIEVITNKFYS STYRKKSELCGNVFKIEYSEERQRLAYVRLYGGILHLRDSVRISEKEKIKITEMYTSINGELCKIDKAYSGEIVILQNEF LKLNSVLGDTKLLPQRERIENPLPLLQTTVEPSKPQQREMLLDALLEISDSDPLLQYYVDSTTHEIILSFLGKVQMEVTC ALLQEKYHVEVKIKKPTVIYMERPLKKAEYTIHIEVPPNPFWASIGLSVAPLPLGSGVQYESSVSLGYLNQSFQNAVMEG IRYGCEQGLYGWNVTDCKICFKYGLYYSPVSTPADFRMLAPIVLEQVLKKAGTELLEPYLSFKIYAPQEYLSRAYNDAPK YCANIVDTQLKNNEVILSGEIPARCIQEYRNDLTFFTNGRSVCLTELKGYYVTTGESVCQPRRPNSRIDKVRYMFNKIT |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| SSU98_0928 | YP_001200485.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| SSU05_0922 | YP_001198287.1 | translation elongation factor (GTPases) | Not tested | 89K | Protein | 0.0 | 96 |
| tetO | AFJ97266.1 | truncated tetracycline resistant protein | Not tested | Not named | Protein | 8e-155 | 75 |
| tet(W) | YP_005160006.1 | tetracycline resistance protein | Not tested | Not named | Protein | 0.0 | 69 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | AM180355.1.gene636.p | Protein | 0.0 | 100 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | X04388.gene.p01 | Protein | 0.0 | 93 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | M85225.gene.p01 | Protein | 0.0 | 91 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | NC_009782.5559075.p0 | Protein | 0.0 | 89 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | NC_002758.1120355.p0 | Protein | 0.0 | 89 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | L09756.gene.p01 | Protein | 0.0 | 80 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | AJ295238.gene.p01 | Protein | 0.0 | 73 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | AY485126.gene.p01 | Protein | 0.0 | 69 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | AJ222769.gene.p01 | Protein | 0.0 | 69 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | DQ294299.gene.p01 | Protein | 0.0 | 68 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | FN594949.1.gene24.p0 | Protein | 0.0 | 68 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | L42544.gene.p01 | Protein | 4e-123 | 44 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | AJ514254.gene.p01 | Protein | 2e-117 | 43 |
| tetM | YP_001086983.1 | Tetracycline resistance protein Tn5397 | Z21523.gene.p01 | Protein | 2e-103 | 41 |
