Gene Information

Name : CD630_05060 (CD630_05060)
Accession : YP_001086980.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : Reverse transcriptase/maturase/endonuclease,Group II intron
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG3344
EC number : 2.7.7.49
Position : 596830 - 598659 bp
Length : 1830 bp
Strand : +
Note : Evidence 1a : Function experimentally demonstrated in the studied strain; PubMedId : 12568329,12568327,17650959, 11157942, 11073898, 8863741; Product type e : enzyme

DNA sequence :
ATGACAGTCAAAGTTAGTAACAAAAAGGCACTGAGGTTCAATGAGTATTACGATACTCAGAAAATTCAAGACGAACTCTA
TCAATTATCTGCCGAAGGCAGTCATGTGTTTAGAGATTTAATGAGCTATATCACACAAGAAGAAAATATTTTATTGGCTT
ATCGAAATATCAAAAGCAATAAAGGCAGTAAAACTGCTGGAACAAATAAAAGAACGATTATTGATGTTGGTGAAGAAAAC
CCATATCAATTAGTTCAATACGTTCAAAATCGATTTAACAACTTTCAACCTCACTCCATCAGAAGAGTCGAGATTCCAAA
GCCAAATGGTAAAACCAGACCGCTAGGAATCCCAACAATTGAGGATAGATTAGTACAGCAATGCATAAAGCAGATCCTTG
AACCAATTTTGGAAGCAAAATTCCATAAGCATTCTTATGGATTTCGACCAGAAAGAAGTTCGCACCATGCCATAGCGATA
TTTCAGCAATGGACATTTAAAGGATTTCACTATGTAGTGGACATTGATATTAAGGGCTTCTTTGACAATGTAAATCATGG
AAAATTGCTTAAGCAACTCTGGACAATGAAAATTCGAGACAAGACATTTATTTCAATATTGTCGAGAATGCTTAAGGCAG
AGGTAAAAGGCATTGGAAAATCAACCAAAGGAACCCCACAAGGTGGTATTCTTTCTCCTCTTTTAGCTAATGTGGTGCTA
AACGAATTAGATTGGTGGATAGATAGTCAGTGGGACGGATTTCCAACCAAAAGAAAATACAGTAGTCTGCTGAGTAAAAC
TCAATCAATAAGAAAGTATTCAAACTTGAAAGAAATCAAAATTGTCCGTTACGCAGATGATTTCAAAATCATGTGCAAAG
ATTATCATACTGCCCAGAAAATTTTCCTCGCAACAAAACAATGGTTAAAAGTACGACTTGATTTAGACATAAGTCCTGAA
AAGTCAAAAGTAACTAATCTGAGAAAAAATTATTCTGACTTTCTAGGATTCAAGTTGAAAGTGAAAAAAGGAAAAGCAAA
CGGATATACCAATCGAAGCCGAATGTGTGATAAGGCAAAGATTAATGCGGTAGATAAACTAAAGAACAATATCAAAACAA
TCGCCGCTAATCCAACTGTAGATAATGTCAATAAGTACAACTCTGTTGTTCTAGGTTTGCATAACTATTATAAAATTGCG
ACTCTGGTCAACTTAGATTTTGTAGATATTGCTTTCACAGTAAATAAAAGTCTTGATTGTCGAACCAAAAATATTCGCAA
TAAGCACGGAACGCTAACCAGTACCTATCAAAAATTCTATAAACAATATAACTGGAAGAAACGATTCATAGCGAACATGA
TTTTATTTCCAATAGCCGGGATAAAATTTACAATGCCAAGAATCTTTCCGAAGGACTGGAATCGATATACGCCTGAAGGT
AGGCTGTTTATTCATCAAAGATTAAAGATGGATATGCATACCGTTTATTACCTGCTGGAAAATTCCAATCCGAATAAGTC
TGTAGAATTTAACGATAATCGAATCTCTCTGTTCATAGCCCAACAAGGAAAATGTCATGTTAGTGGTGAAAATTTATCAA
AAGATAATATGGAAGTTCATCACATTAAGCCGTTATCACTTGGTGGGAATGATAACTATAAGAATCTTGTGATTGTTACA
AAAGAAACACACAAATTGATTCATGCGACTAAAAGAGAAACGATAGTTCATTATTTACCTTTGGTATTAAAAAAGGAAAG
ATCATTGGAAAAGCTGAATAAATTACGTGCTTTAGCTGGGAATAGTGAAATAGAAATGAATTACTGTTGA

Protein sequence :
MTVKVSNKKALRFNEYYDTQKIQDELYQLSAEGSHVFRDLMSYITQEENILLAYRNIKSNKGSKTAGTNKRTIIDVGEEN
PYQLVQYVQNRFNNFQPHSIRRVEIPKPNGKTRPLGIPTIEDRLVQQCIKQILEPILEAKFHKHSYGFRPERSSHHAIAI
FQQWTFKGFHYVVDIDIKGFFDNVNHGKLLKQLWTMKIRDKTFISILSRMLKAEVKGIGKSTKGTPQGGILSPLLANVVL
NELDWWIDSQWDGFPTKRKYSSLLSKTQSIRKYSNLKEIKIVRYADDFKIMCKDYHTAQKIFLATKQWLKVRLDLDISPE
KSKVTNLRKNYSDFLGFKLKVKKGKANGYTNRSRMCDKAKINAVDKLKNNIKTIAANPTVDNVNKYNSVVLGLHNYYKIA
TLVNLDFVDIAFTVNKSLDCRTKNIRNKHGTLTSTYQKFYKQYNWKKRFIANMILFPIAGIKFTMPRIFPKDWNRYTPEG
RLFIHQRLKMDMHTVYYLLENSNPNKSVEFNDNRISLFIAQQGKCHVSGENLSKDNMEVHHIKPLSLGGNDNYKNLVIVT
KETHKLIHATKRETIVHYLPLVLKKERSLEKLNKLRALAGNSEIEMNYC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2326 NP_815981.1 group II intron reverse transcriptase maturase Not tested Not named Protein 1e-111 47
ef0012 AAM75218.1 EF0012 Not tested Not named Protein 9e-79 41