Gene Information

Name : spaF (CD630_04780)
Accession : YP_001086952.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : ABC transporter lantibiotic/multidrug-family ATP-binding protein
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG1131
EC number : -
Position : 567177 - 567881 bp
Length : 705 bp
Strand : +
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 17135193, 17577060, 17046525, 17096664,18336322,11781802, 18504552, 18952792, 8384683; Product type t : transporter

DNA sequence :
ATGAAAGATTTAATTCTTGAAACAAAAAACTTATCAAAAAGATATGGAGAACAAATGGCAGTTAACAATGTTTCTCTACA
AATTGAACGAAATAGTATATATGGACTTTTAGGACCAAATGGAGCAGGAAAGTCCACAACACTTAAAATGCTTGTTGGTC
TTCTTCGCCCAACAAATGGTCGTATTATTTTTGATAGAAAGCCTTGGAAACGAGAATCTCTTGCAAAAATAGGTTCTTTA
ATAGAATCCCCTGCATTGTATGGAAACCTTACAGCAGAGGAAAATTTGTTAGTACATACAAAAATATTGGGAATACCTAA
AGATAAAATTTATGAAGTGTTGGAAATAGTAAATTTGAAAAATACAGGTAAAAAGAGAGCTTCACAATTTTCTATGGGTA
TGAAACAAAGGTTAGGAATAGCTATTGCACTTTTGAGTGACCCAGAGTTGTTAATACTAGATGAACCAACCAATGGTCTT
GACCCCTTTGGCATTCAAGAATTGCGTGAATTGATTGCTTCTTTTCCAAAAAAAGGTATAACTGTAATTCTTTCTAGCCA
TATTCTATCAGAGGTTGCTCAAGTTGTAGATAATATAGGAATTATAAATGGAGGACGACTATTATTTCAAGGAATGCCTG
ACCCTAATGAAAATCTAGAAGAATTTTTTACAGATGTTATTCTTAAAGGAGGACAAAACAGATGA

Protein sequence :
MKDLILETKNLSKRYGEQMAVNNVSLQIERNSIYGLLGPNGAGKSTTLKMLVGLLRPTNGRIIFDRKPWKRESLAKIGSL
IESPALYGNLTAEENLLVHTKILGIPKDKIYEVLEIVNLKNTGKKRASQFSMGMKQRLGIAIALLSDPELLILDEPTNGL
DPFGIQELRELIASFPKKGITVILSSHILSEVAQVVDNIGIINGGRLLFQGMPDPNENLEEFFTDVILKGGQNR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cdd4 CAA63569.1 - Not tested PaLoc Protein 3e-47 53
epiF YP_186701.1 epidermin immunity protein F Virulence vSa¥â Protein 3e-40 49
bsaF NP_646577.1 hypothetical protein Not tested vSa¥â Protein 3e-40 49
epiF YP_494453.1 lantibiotic epidermin immunity protein F Not tested vSa¥â Protein 3e-40 49
bsaF YP_001332745.1 lantibiotic immunity protein F Not tested vSa¥â Protein 2e-40 49
SPN23F_09830 YP_002510959.1 lantibiotic transport ATP-binding protein Not tested PPI-1 Protein 4e-33 46
CD241_0087 YP_005124356.1 ABC transporter ATP-binding protein Not tested Not named Protein 2e-36 43
Spaf_1123 YP_006309925.1 putative transport ATP-binding protein Not tested FWisland_1 Protein 8e-30 42
DIP0090 NP_938487.1 ABC transporter ATP-binding protein Not tested Not named Protein 1e-36 41