Gene Information

Name : blaI (CD630_04710)
Accession : YP_001086944.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Resistance
Product : penicillinase transcriptional regulator
Function : -
COG functional category : K : Transcription
COG ID : COG3682
EC number : -
Position : 562228 - 562614 bp
Length : 387 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14568532, 12881514, 7876197; Product type r : regulator

DNA sequence :
ATGAAAAAGTTACCACATATTTCAGAAGCAGAATATCAAGTTATGAAAATTATTTGGAAATATGCTCCTATCAGCACTAC
TGAAGTAATTGAAAAGTTGGTAGAAACAAGTACATGGAGTCCTAAAACAATTCAAACAATGTTATTGAGATTAGTTAAAA
AAGGAGCTTTAACATATGAAAAAAATAGCAGAGTATTCGTTTATACTCCACTTGTTAAAGAAGAAGAATACGTAGCTACA
GAAAGTAGTTCTTTTTTAAATCGTTTTTATAATGGTACTCTTAATTCTATGGTACTAAACTTTTTAGAAAATGATAAACT
ATCTGAAGATGATATTGAGGAACTGAGAGAAATCTTAAATAAAAGGACGACTAAGGGGGATAAATAA

Protein sequence :
MKKLPHISEAEYQVMKIIWKYAPISTTEVIEKLVETSTWSPKTIQTMLLRLVKKGALTYEKNSRVFVYTPLVKEEEYVAT
ESSSFLNRFYNGTLNSMVLNFLENDKLSEDDIEELREILNKRTTKGDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
mecI NP_370567.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 1e-19 48
mecI NP_373280.1 methicillin resistance regulatory protein Not tested Type-II SCCmec Protein 3e-20 48
mecI YP_190060.1 methicillin-resistance regulatory protein MecI Not tested Type-II SCCmec Protein 3e-20 48
mecI BAA82218.1 methicillin resistance protein MecI Not tested Type-II SCCmec Protein 2e-20 48
mecI YP_039517.1 methicillin resistance regulatory protein MecI Not tested Type-II SCCmec Protein 1e-16 46
mecI YP_005754043.1 methicillin resistance regulatory protein MecI Not tested Type-XI SCCmec Protein 9e-19 46

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
blaI YP_001086944.1 penicillinase transcriptional regulator AM180355.1.gene595.p Protein 7e-55 100
blaI YP_001086944.1 penicillinase transcriptional regulator NC_009782.5560220.p0 Protein 4e-20 48
blaI YP_001086944.1 penicillinase transcriptional regulator NC_002758.1120003.p0 Protein 4e-20 48
blaI YP_001086944.1 penicillinase transcriptional regulator NC_002745.1122814.p0 Protein 1e-20 48
blaI YP_001086944.1 penicillinase transcriptional regulator NC_002952.2861158.p0 Protein 4e-17 46
blaI YP_001086944.1 penicillinase transcriptional regulator FR823292.1.gene6.p01 Protein 3e-19 46
blaI YP_001086944.1 penicillinase transcriptional regulator CP001581.1.gene771.p Protein 3e-26 44