Gene Information

Name : CD630_04180 (CD630_04180)
Accession : YP_001086885.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : conjugative transposon protein
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG3451
EC number : -
Position : 487054 - 489447 bp
Length : 2394 bp
Strand : +
Note : Evidence 3 : Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; PubMedId : 12568329, 12568327,17650959, 11157942,11073898, 8863741; Product type h : extrachromosomal origin

DNA sequence :
ATGCAAAACGAAAAGGCATTGAGAAGTCAAAAGCGGGACTTAAAGAAAAGTAATTGCAAGTCAAAAAAAGATAAGGGAGG
AATCCTTGACCTTATCTTTAAGAAAGAACCGAAAAGATATACGGTAGAAGATACCATTCCCTATCTAAGGCTTTTAAAAA
GCGGAATATGCCAGCTTGATGAAAAGCACTTCAGTAAAAGTATAGCCTTTCAGGACATTAACTATCAGCTTGCCTTAGAT
GAAGATAGGGACTTGATTTTTAATCAATTTGCAAACTTCCTAAACTCTTTTGATCCAAGTATCAGCATTGAGTTTTCATA
TGTCAATCAGCTCGGACGAAACGAAGAAATGAAGTCGGCAATTCAGATACCGGATAAAAAGGACGGTTTTGACGATATAC
GCTTTGAATTTAGAGAGATGCTTAAAAGCCAGATTGTAAAGGGAAATAACGGACTTAAAAAATCAAAGTATGTAACCTTT
ACAGTGGAAGCGGATAATTTAGAGCAGGCAACATCAAAACTTGAAAGACTGGAGATAGATATATTATCTAATCTAAAGAG
CATGGGTGTGAGAGCAGAAAGCCTAAACGGAGAAGAAAGGCTAAAGATACTTCATGATGTTTTAAATCCAAATAAAACAT
TTGAATTTTCCTACAAAGACCTAAAGAAAAGAGAAAGCACAAAGACATATATTGTGCCTGATGAGTTTAACTTTACACCG
AGTAGATACTTTAAGTTCGGCAAATTCATCGGAGCAACAAGTCATTTTCAAATCCTTGCCAGTGAGCTTTCAGATAGGAT
GTTATCCGAGTTTTTGGATATTGACGATAACATCAATATTTCCTTTCATATTAGGGCAATCGACCAATCGGAAGCCATTA
AGATGGTAAAACGAAAAAACACTGATATTGATAAGATGAAGATTGAGGAAAATAAGAAGGCGGTAAGAAGCGGTTATGAT
ATGGACATTCTTCCATCAGACTTAATTACCTATGGTGAGGATGTAAAGAGCCTTTTAAAAGACTTGCAGACAAGAGATGA
GCGAATGTTTGTGGTAAGTATCGTCTTTATGAACTTTGCAAGGACAGTGCAAAAGCTCGATAACACAATTGCTCAAATAA
GCTCCATTGCAAATAAGCATAACTGTAAGCTGAAAAGACTTGACCATTCTCAGGAACAAGGTTTAGTGAGCATGCTGCCT
CTTGGTGTAAATAAGATTGAGATAGATAGAGGACTGACAAGCTCATCAACGGCAGTATTTATGCCATTTACCACAGAGGA
GCTTTTTATCAATTCAAGTAATAGTCTTTACTACGGACTAAATGCCCTAAGCCATAACCTGATTATGGCAGATAGAAAGA
AATTAAAGAACCCAAACGGTCTAATCCTCGGAACTCCGGGCAGCGGTAAATCCTTTAGTGCCAAAAGAGAAATGGCAAAT
GCGATTTTAGTAACAGATGATGATGTGATTATCTGCGATCCGGAAGGAGAGTATGGAAATCTCGTAAGGCAGTTTAAGGG
AGAAGTCATTAAGGTCAGCAGTAAGTCAAAGGATTACCTGAATCCCCTTGATATAAACATGAACTACGGTGATGGGGATG
CACCGCTGAAAGACAAGGCAAACTTTATCATGAGTATGCTTGAGCTTGTAGTAGGTGGTAGTGGTCTTACAGCAGAAGAA
AAGTCCGTTATAGATAGGTGCCTTCCTAAAATCTATGAAAAGTATTTTGAACATCCTACTCCTGACAATATGCCGATACT
TCAAGACCTATACGATATGTTAAAAGGGCAGGAAGAAAAGGTCGGTAAGAAGCTGGCAACAGAGATGGAAATCTATGTAT
CGGGTTCTCTCAATGTCTTTAATCACAGGTCAAATGTGGATTTAAATAAGAAGCTGCTTTGTTTTGATATTAAGGAGCTT
GGAAGTCAGCTAAAGAAAATAGGAATGCTTGTCATTCAGGATCAGGTGTGGAATAAGGTGTCACAAAACAGGGGAAACAA
GGCTACAAGATACTATATCGACGAATTTCACCTGCTGTTAAAAGATGAGCAGACAGCTTCATACTCGGTTGAGATATGGA
AGAGGTTTAGAAAATGGGGAGGTATCCCGACAGGTATCACGCAAAATGTCAAAGACCTACTTATGAGTAAGGAGATAGAA
AATATTTTTGATAATACGGACTTTGTCTTAATGTTAAATCAGGCTTCGGGAGATAGAGAAATCTTAGCAAGGAAACTTAA
AATCTCACTTCCACAGCTCAGATATGTTACTAATTCAAATGAAGGTGAGGGACTACTTTTCTTTGGAAATACCATTGTGC
CTTTCCTTGATAAGTTTCCGAAAGATACGATTCTTTATCAGAAGATGACTACCAAGCCGGAAGAAGTGAGGTAG

Protein sequence :
MQNEKALRSQKRDLKKSNCKSKKDKGGILDLIFKKEPKRYTVEDTIPYLRLLKSGICQLDEKHFSKSIAFQDINYQLALD
EDRDLIFNQFANFLNSFDPSISIEFSYVNQLGRNEEMKSAIQIPDKKDGFDDIRFEFREMLKSQIVKGNNGLKKSKYVTF
TVEADNLEQATSKLERLEIDILSNLKSMGVRAESLNGEERLKILHDVLNPNKTFEFSYKDLKKRESTKTYIVPDEFNFTP
SRYFKFGKFIGATSHFQILASELSDRMLSEFLDIDDNINISFHIRAIDQSEAIKMVKRKNTDIDKMKIEENKKAVRSGYD
MDILPSDLITYGEDVKSLLKDLQTRDERMFVVSIVFMNFARTVQKLDNTIAQISSIANKHNCKLKRLDHSQEQGLVSMLP
LGVNKIEIDRGLTSSSTAVFMPFTTEELFINSSNSLYYGLNALSHNLIMADRKKLKNPNGLILGTPGSGKSFSAKREMAN
AILVTDDDVIICDPEGEYGNLVRQFKGEVIKVSSKSKDYLNPLDINMNYGDGDAPLKDKANFIMSMLELVVGGSGLTAEE
KSVIDRCLPKIYEKYFEHPTPDNMPILQDLYDMLKGQEEKVGKKLATEMEIYVSGSLNVFNHRSNVDLNKKLLCFDIKEL
GSQLKKIGMLVIQDQVWNKVSQNRGNKATRYYIDEFHLLLKDEQTASYSVEIWKRFRKWGGIPTGITQNVKDLLMSKEIE
NIFDNTDFVLMLNQASGDREILARKLKISLPQLRYVTNSNEGEGLLFFGNTIVPFLDKFPKDTILYQKMTTKPEEVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
EF2320 NP_815976.1 traE protein Not tested Not named Protein 0.0 59
EFAU085_00716 YP_008394240.1 Type IV secretory pathway, VirB4 component Virulence Not named Protein 0.0 52