Gene Information

Name : dnaB (CD630_36570)
Accession : YP_001090181.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : replicative DNA helicase
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0305
EC number : 3.6.1.-
Position : 4268087 - 4269415 bp
Length : 1329 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 20129058, 20071750, 19968790, 6541161; Product type e : enzyme

DNA sequence :
ATGGAAGATATGACGAGAATTCCTCCTCATAGTGTAGAATCAGAACAATCAATATTGGGTTCTATACTTCTAGATAAAGA
TGCTATAATAACGGTTACAGAAACTATAAAGCCTGATGATTTCTATAAAGAGGCTCACAAAATAATATATGAATGTATGA
TAACTTTAAGTAATAAAGGTGAGCCTATAGACTTGATAACATTAACAGAAGAACTAAGAAAACAAGGGCATCTTAATGAT
ATTGGAGGAATCAGTTATATTACAAGTCTTTCTACTATAGTACCGACGACTTCAAATGTAAAATACTATGCTGATATAGT
AAAAGAAAAGTCTGTACTTAGAAAGCTTATAAAAGCTTCTAATGAAATAATAAATCTAGGATATAGTGGAGCAACTAAGA
TTGAAGATGTTTTAGAACAAGCTGAAAAGAGTATATTTGATATATCACAGGAGAAAACTAGTGATGATTTTAAATCTATA
AACTTAGTTTTGATGGATGCCTATGATATGATAGAAAAATTATACACTAACAAGAGTGATGTCACTGGTATAACTACTGG
TTTTAAAGATTTAAACAAAAAAATAAATGGTCTTCAAAGGACTGATTTAATATTAATTGCAGCTAGACCAGCAATGGGTA
AAACTGCCTTTTCTTTAAACTTGGTTCAAAATGCAGCCTTAAAAGGTGATGCCTCTGTAGCTGTATTTAGTTTAGAGATG
TCTAAGGAACAATTAGTACAACGTATGTTATCTTCACAATCTAGTGTAGAATTAAAAAAAATAAAGACTGGAACACTTAA
TGATAATGATTGGCCTAGAATTATAGATGCTATGGCAGTATTATCAGATGCCAAAATACACATAGATGATACTCCTGGTA
TAAAAATATCAGAACTAAGGTCAAAGTGTAGAAAGTTAAAAATAGAAAAAGGACTAGATTTAGTGCTTATTGATTATCTT
CAACTTATGGAAGGTGAAGGTAATAATGAAAGCAGACAACAAGAGATATCTAAGATATCAAGGTCACTAAAAATATTAGC
AAAAGAATTAAACTGTCCTGTAGTAGCACTATCTCAGTTATCACGTGCACCAGAACAAAGAGCAGACCATAGACCTATGT
TATCTGATTTAAGAGAGTCTGGAGCAATAGAACAGGATGCAGATATAGTTATGTTCTTATACAGGGACGAATATTATCAT
GCTGATTCTGAGAGTAAAAATATAGGAGAAGTAATAATAGCAAAAAATAGACACGGTGAAACTGGTTCTGTGGAACTTGT
TTGGCTTGGTGAAGTTCAAAGATTTGGGGATAAGTTGAGAGACCTATAA

Protein sequence :
MEDMTRIPPHSVESEQSILGSILLDKDAIITVTETIKPDDFYKEAHKIIYECMITLSNKGEPIDLITLTEELRKQGHLND
IGGISYITSLSTIVPTTSNVKYYADIVKEKSVLRKLIKASNEIINLGYSGATKIEDVLEQAEKSIFDISQEKTSDDFKSI
NLVLMDAYDMIEKLYTNKSDVTGITTGFKDLNKKINGLQRTDLILIAARPAMGKTAFSLNLVQNAALKGDASVAVFSLEM
SKEQLVQRMLSSQSSVELKKIKTGTLNDNDWPRIIDAMAVLSDAKIHIDDTPGIKISELRSKCRKLKIEKGLDLVLIDYL
QLMEGEGNNESRQQEISKISRSLKILAKELNCPVVALSQLSRAPEQRADHRPMLSDLRESGAIEQDADIVMFLYRDEYYH
ADSESKNIGEVIIAKNRHGETGSVELVWLGEVQRFGDKLRDL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
PMI2640 YP_002152342.1 DNA helicase Not tested Not named Protein 1e-74 43
unnamed ABR13456.1 replicative DNA helicase Not tested PAGI-5 Protein 1e-85 42
STY4522 NP_458617.1 DNA helicase Not tested SPI-7 Protein 3e-73 42
t4227 NP_807829.1 DNA helicase Not tested SPI-7 Protein 3e-73 42
dnaB2 YP_001402701.1 replicative DNA helicase Not tested YAPI Protein 7e-77 42
api2 CAF28476.1 putative DNA binding protein with DNA-dependent ATPase activity Not tested YAPI Protein 3e-77 42