Gene Information

Name : lysS (CD630_35520)
Accession : YP_001090075.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : lysyl-tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 4152690 - 4154219 bp
Length : 1530 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 12762020, 7576245; Product type e : enzyme

DNA sequence :
ATGAAAAATAATCAACAAAGCAATGAAGAAGCGCAAATTCAAGAAGACCTTAGTGAAGTACTTCAAGTAAGAAGAGATAA
ACTAAAAAAATTACAAGAGTCAGGTAGAGATCCTTTTAAAGAAAGTAGATATGATAGAACGCATTATTCTATGGATATAA
AAGATAACTTTGATTCTCTTGAGGGTAAAACTACAAAAATAGCAGGACGTATAATGAGCAAGAGAATACAAGGGAAAGCT
GGCTTTATAGATATTCAAGACCAAGAGGGAAGAATCCAATCTTATGTAAGACTAGATGCTATAGGAGAGGAAGAATATAG
TGTATTTTCAACATATGATATTGGAGATATAGTTGGAATTGAAGGAGAAATCTTTAAAACTAAAAAAGGTGAAATATCTG
TAAAGGCTAAATCTGTAGTATTACTATGTAAATCTTTACAAGTTTTACCAGAAAAATATCATGGATTAAAAGACCAAGAA
CTAAGATATAGACAAAGATATGTTGACTTAATAGTAAATCCAGAAGTAAAAAATGCTTTTTTAATTAGAACAAAAGCATT
AAAAGCATTAAGAGCATACTTAGATGATAGAGGATTTTTAGAAGTTGAGACTCCAATATTAAATACTATAGCAGGTGGGG
CAAATGCTAGACCATTTATAACTAATCATAATACTTTACATATACCAATGTATTTAAGAATAGCGAATGAATTGTATTTA
AAAAGACTTATTGTTGGTGGATTTGATAAAGTTTATGAAATGGGAAGAATGTTTAGAAATGAAGGTATGGATTTAAAACA
TAATCCTGAATATACTGCAATAGAATTATATCAAGCATATGCAGACTATACTGATATGATGGAAATAACAGAAAATGTTA
TTGCACATATGGCTGAAGTTGCTACAGGAAGTATGATAGTTAACTATCAAGGAACAGAAATAAACTTTACACCACCTTGG
AAAAGAATGAGTATGGAAGATTGTGTTAAAGAATATTCTGGTGTAGATTTTTCTACTATAAATACAGATGAAGAGGCACT
AGAAGTTGCTAGAGAAAAAGGTATAGAGATAAAACCTGGAATGAGAAGAGGAGAAGTAATAAATGCTTTCTTTGAAGAAT
TTGGAGAAGATAAATTAATCCAACCAACATTTATAACTCATCATCCAGTTGAAGTATCTCCATTATCTAAGAGAAATGTT
GAAGACCCAAGAAGAACTGATAGATTTGAGGCATTTGCTAATAAGTGGGAGTTAGCTAATGCATTTTCTGAACTTAATGA
CCCTATTGACCAAAAAGGAAGATTTATAGACCAATTAAGAAAAAGAGAATTAGGTGATGATGAAGCTTTTGAAATGGATG
AAGATTTCTTAAAAGCATTAGAGGTAGGTCTACCTCCTACAGGAGGACTAGGAATAGGTATAGATAGAGTAATTATGTTA
TTAACTAACTCTCCATCTATAAGAGATGTATTATTATTCCCGACTATGAAACTTATTGATAACAATTCAAATAAAGAAGA
AGAAAACTAA

Protein sequence :
MKNNQQSNEEAQIQEDLSEVLQVRRDKLKKLQESGRDPFKESRYDRTHYSMDIKDNFDSLEGKTTKIAGRIMSKRIQGKA
GFIDIQDQEGRIQSYVRLDAIGEEEYSVFSTYDIGDIVGIEGEIFKTKKGEISVKAKSVVLLCKSLQVLPEKYHGLKDQE
LRYRQRYVDLIVNPEVKNAFLIRTKALKALRAYLDDRGFLEVETPILNTIAGGANARPFITNHNTLHIPMYLRIANELYL
KRLIVGGFDKVYEMGRMFRNEGMDLKHNPEYTAIELYQAYADYTDMMEITENVIAHMAEVATGSMIVNYQGTEINFTPPW
KRMSMEDCVKEYSGVDFSTINTDEEALEVAREKGIEIKPGMRRGEVINAFFEEFGEDKLIQPTFITHHPVEVSPLSKRNV
EDPRRTDRFEAFANKWELANAFSELNDPIDQKGRFIDQLRKRELGDDEAFEMDEDFLKALEVGLPPTGGLGIGIDRVIML
LTNSPSIRDVLLFPTMKLIDNNSNKEEEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 5e-98 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001090075.1 lysyl-tRNA ligase VFG1668 Protein 3e-98 47