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Name : pyk (CD630_33940) Accession : YP_001089914.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Virulence Product : pyruvate kinase Function : - COG functional category : G : Carbohydrate transport and metabolism COG ID : COG0469 EC number : 2.7.1.40 Position : 3969026 - 3970786 bp Length : 1761 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16333337, 15158258, 12798932, 7559366; Product type e : enzyme DNA sequence : ATGTTAAATAATGTAAAGAAGACAAAAATTGTTTGTACACTAGGTCCAGCATCACAAAGTGAGGAAGTTTTAACTCAACT TATGCAAAATGGTCTAAATGTGTGTAGATTTAACTTTTCTCACGGTTCGCATGAAGAACATAAAGAAAGAATTGATATGG CAAAGAAAGTTAGAGAAAAATTAAATAAGCCAGTTGCTATATTATTAGATACTAAAGGTCCAGAAATTAGAACAGGTAAC TTTGAAGACCCAGAGGTATTTTTAGAAGAAGGGCAAAAGTTCACTATAACTATGAAAGATATTATGGGGACTAAAGAAAT GTGTACAGTAAGCTATAAAGGTCTTGCTGAAGACGTTAAATCAGGAGATTCTATACTAATAGATGATGGTTTAGTTGGCT TAAGAGTAAAAGAAATAAATGGAGAAGATATAGTTTGTGTTGTTGAAAATTCAGGAATAGTTAAAAATCATAAAGGAGTA AATGTACCTGGTGTTAAGATAAATTTACCAGCAATAACTCCTAAAGATATAAGTGATATAGAGTTTGGAATAAGTCAAGG AATAGATTATATAGCTGCTTCTTTTGTAAGAAAGGCATCTGATGTACTAGCAATAAGAGAAGTATTAGAGAACAATAATG CAACTGATATACAAATAATATCTAAAATAGAAAACCAAGAAGGTGTAGAGAACCTAGATGAAATATTAAAAGTTTCTGAT GGTATAATGGTGGCTAGAGGTGACTTAGGTGTTGAGATACCAACTGAAGAGATGCCAATAGTTCAAAAAATGATGATAAA AAAATGTAATGAATTAGCAAAGCCAGTTGTTACTGCCACTCAAATGCTTGATTCTATGATAAGAAATCCAAGACCAACAA GAGCAGAAGTTACAGACGTTGCCAATGCTATATATGATGGAACAGATGCGATAATGTTATCTGGAGAAACTGCTGCTGGA AAATATCCTGTAGAGGCAGTAAAAATGATGGCTACAATAGCAAAAAGAACAGAAGAGACTTTAGATTATGATAGATTACT AAAGGAAAATGGTACTAACAATGTTACTGTAACAGATGCAATAAGCCATGCAACTTGTACAACAGCAGTAGATTTAAATG CATCAGCTATAATAACATCTACTTCTTCAGGATATACTGCTAGAATGGTATCTAAATTCAGACCAAAATCTCCAATAATA GCTACTACAAATAATGAAAAGACTATGAATAAATTAGCTCTTACATGGGGAGTATATCCAGTTAAGTCTTCTGTTGCAGG AAATACAGATGAAGTTATAGAAAAGGCAATTGAGGCAGCTAGACAAGCTGATTATATAGATAATGGGGAATTAGTAGTTA TAACTGCTGGAGTACCAGTAGGAGTAAGTGGAACTACTAATTTAATAAAGGTTCATGTAATAAGCGAAGAAATCGTGCAA GGTATAGGTGTAGGTACTCAAACAGTAGAAGGTAAAGTTCGTATAATAAAGAATGGAAATGCTTGTGTAGACTTTAATGA AGGCGACATACTTGTTTCTACTGCTACTGATGCTGAAATGAACAATTATATAGAAAAAGCAGGAGCTGTAGTAACTGAGA ATGGTGGAATGACATCACATACAGCTATTGTAGGTATAAATTTAGATATACCAGTTATTGTGTCTGCAGCTGATATAACA AATCTAGTAAAAGATGGAGAAGTTGTAACTGTGGATGCATCAAGAGGCGTGGTATATAGAGGTTCAACTAGAGTTTTATA A Protein sequence : MLNNVKKTKIVCTLGPASQSEEVLTQLMQNGLNVCRFNFSHGSHEEHKERIDMAKKVREKLNKPVAILLDTKGPEIRTGN FEDPEVFLEEGQKFTITMKDIMGTKEMCTVSYKGLAEDVKSGDSILIDDGLVGLRVKEINGEDIVCVVENSGIVKNHKGV NVPGVKINLPAITPKDISDIEFGISQGIDYIAASFVRKASDVLAIREVLENNNATDIQIISKIENQEGVENLDEILKVSD GIMVARGDLGVEIPTEEMPIVQKMMIKKCNELAKPVVTATQMLDSMIRNPRPTRAEVTDVANAIYDGTDAIMLSGETAAG KYPVEAVKMMATIAKRTEETLDYDRLLKENGTNNVTVTDAISHATCTTAVDLNASAIITSTSSGYTARMVSKFRPKSPII ATTNNEKTMNKLALTWGVYPVKSSVAGNTDEVIEKAIEAARQADYIDNGELVVITAGVPVGVSGTTNLIKVHVISEEIVQ GIGVGTQTVEGKVRIIKNGNACVDFNEGDILVSTATDAEMNNYIEKAGAVVTENGGMTSHTAIVGINLDIPVIVSAADIT NLVKDGEVVTVDASRGVVYRGSTRVL |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| pykF | NP_805051.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-103 | 51 |
| pykF | CAA68205.1 | pyruvate kinase like protein | Not tested | SPI-2 | Protein | 6e-103 | 51 |
| STY1744 | NP_456147.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-103 | 51 |
| pykF | YP_216386.1 | pyruvate kinase | Not tested | SPI-2 | Protein | 1e-103 | 51 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| pyk | YP_001089914.1 | pyruvate kinase | VFG0479 | Protein | 4e-104 | 51 |
