Gene Information

Name : nrdE (CD630_29950)
Accession : YP_001089513.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : ribonucleoside-diphosphate reductase subunit alpha (Ribonucleotide reductase large subunit)
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 3477847 - 3479946 bp
Length : 2100 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 16885274; Product type e : enzyme

DNA sequence :
ATGAATTGGATAGAGCTTAACAATCAAGTGATAATTAAAAATGAACAAGGCAAGTACCAATTGGAAAAGGATAAGGAAGC
CTTAAGTAGTTACATAGAAGAATTTATACAGCCAAAGTTGAGAAAATTTAATAACCTAGAAGAAAGATTGAAGTATTTAA
TAGATGAAGGTTATTATTCAAAAGAAGTAATAAATCAGTATAGCATAGATGTTATTAAAAATATATATGATATGATTGAT
AAACATAAGTTTGAATTTCAATCATATATGAGTGTAAATAAGTTTTATCAAAATTATGCATTAAAGAGCAATGATGGAAA
GGAAATATTAGAAACATATAATGATAAAGTGTTAATTGTAGCTTTGACACTAGGAAATGGCAATAAAGATTTAGCTTTAA
ACTTGGCAGATAAAATAGTAAAACAAGAATTTCAACCAGCTACACCTACTTTTTTAAATGCTGGAAGAAAAAGGGCTGGA
GAAATGGTATCATGTTTTTTACTATCTGTAGAAGATAGTACAGAAGGTATATCGTATGCTATATCTTCATCAAATCACTT
ATCAAAGATTGGTGGAGGAGTTGCACTAAATTTATCTAAACTTAGAGCATCTGGCGAATCTATCAAAGATATAGAAGGTG
CAGCTGGAGGTGTTGTTGGAGTAGCTAAAATGTTAGAACAATCATTTAGTTACTTTAATCAAATGGGAGCTAGACAAGGT
TCTGGTGCGGTGTACCTTACTGTATTCCATCCTGATTTTGAATTGTTGATGGATACTAAAAAGATAAATGCAGATGAAAA
AATAAGGCTTGCTACATTATCATTAGGAGCTATAATACCAGATAAATTTATGGAGTTGGCAGAAAAAAATGAAGTAGCAT
ATGCATTTTATCCTCATACTGTGTATAAGAAATATGGAGTTTCTCTTGATGAGATAGAAATGGATGAGTGGTATGATAAA
TTGGTTAATGATAGTGATATAAGAAAAAAAGAAATAAATCCTAGGCAGATGTTGACAAAAATAGCACAGATGCAACAAGA
AAGTGGATATCCATATGTAGTGTACATAGATACAGCTAATAGAGAACATACATTAAAAGATGTTGGAATTATTAAAATGT
CTAACTTATGTTGTGAGATATTTCAATATCAAACACCTTCAGAAATAGAGGGGTATGGAGGAAAAAATGAATGGGGACAA
GATATAAGTTGTAACCTAGGTTCTTTAAACATAGCTAATGTAATGGATAATAAAACTATAGAAAGTACAGTTGAAACAGC
AATAAGAGCACTGTCATTTGTAGCAGATAGCACAGATATAAAACCAGTGCCAACGGTAAGCAATAGTAACAGCAAGTCTC
ATTCTATAGGATTAGGAGCTATGAATTTACATGGATACTTAGTAAGAGAAAATATTTTATATACTTCAGATGATGCTATA
GATTTTTCTAATGTATTTTTTGCAATGGTTAGATACTATTCAATTAAAGCTTCTATGAAAATAGCCATAGAAAGAAATCA
AACTTTTGAAGGATTTGATAAATCAGAATATGTTAAGGGAAGAAATAGCAAGGTTTTATCAAAATACTATGAACAATCTT
ATCTACCTAAGTCAGAAAAGGTAAGAGCATTATTTGAAGGGATTTATATACCAACAAAAGAAGACTGGACAAAATTATTG
GATGAAGTAAAAGAAAAAGGGATATATAATGCATATTTAATGGCAGTAGCACCAACTCAAAGCATTAGTTATGTTCAAAA
TGCTACATCAAGTATAATGCCAATTACTGAGCCAGTAGAAGTAAGAACATATGGAGACTCTACTACAATATATCCAATGC
CATTTTTAACAAATGATAATATGTTGTATTATCAATCAGCATACAGGATGGATATGAGAAAGGTCATAGATTTAGTGGCA
ACAGTTCAAAACCATGTTGACCAAGGTATATCAACAACACTGTTTGTTACAGATGAAAAGACAACTAGAGATATAGCTAG
ACATTATATATATGCCTATAAAAAAGGTTTGAAAAGTTTATATTACACAAGAACAAAGATGACAAGAGATACTCATGAGT
GTCTAGTGTGTTCAGTATAG

Protein sequence :
MNWIELNNQVIIKNEQGKYQLEKDKEALSSYIEEFIQPKLRKFNNLEERLKYLIDEGYYSKEVINQYSIDVIKNIYDMID
KHKFEFQSYMSVNKFYQNYALKSNDGKEILETYNDKVLIVALTLGNGNKDLALNLADKIVKQEFQPATPTFLNAGRKRAG
EMVSCFLLSVEDSTEGISYAISSSNHLSKIGGGVALNLSKLRASGESIKDIEGAAGGVVGVAKMLEQSFSYFNQMGARQG
SGAVYLTVFHPDFELLMDTKKINADEKIRLATLSLGAIIPDKFMELAEKNEVAYAFYPHTVYKKYGVSLDEIEMDEWYDK
LVNDSDIRKKEINPRQMLTKIAQMQQESGYPYVVYIDTANREHTLKDVGIIKMSNLCCEIFQYQTPSEIEGYGGKNEWGQ
DISCNLGSLNIANVMDNKTIESTVETAIRALSFVADSTDIKPVPTVSNSNSKSHSIGLGAMNLHGYLVRENILYTSDDAI
DFSNVFFAMVRYYSIKASMKIAIERNQTFEGFDKSEYVKGRNSKVLSKYYEQSYLPKSEKVRALFEGIYIPTKEDWTKLL
DEVKEKGIYNAYLMAVAPTQSISYVQNATSSIMPITEPVEVRTYGDSTTIYPMPFLTNDNMLYYQSAYRMDMRKVIDLVA
TVQNHVDQGISTTLFVTDEKTTRDIARHYIYAYKKGLKSLYYTRTKMTRDTHECLVCSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 2e-144 47