Gene Information

Name : fhuC (CD630_28750)
Accession : YP_001089388.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Virulence
Product : ABC transporter ferrichrome-specific ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : 3.6.3.-
Position : 3364140 - 3364922 bp
Length : 783 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 15802251, 17135193, 11781802, 18504552,18952792, 8384683; Product type t : transporter

DNA sequence : 
ATGAACTGTATAAATACTAAGAATCTAAATGTATCATATGGAAACACAGATATTATAAAAAATTTAAATTTAAATATACC
AAAAGGAAAAATAACTACCATCATAGGGGCTAATGGTTGTGGAAAATCGACAATACTTAAAACTATAGGTAGAATTATTA
GCCCTAATAGTGGGAAAATATATATAAATGGAGAGGACATCTACAAAAAGAAGTCTAAAGAAATAGCAAAAGATATGGCT
GTACTTCCACAAAGCCCTCAAGCCCCTAGTGGTCTTACCGTTTCAGAATTAATTTCTTATGGAAGATTTCCTCATAAAAG
TGGATTTGGTAATTCTAGTAAAGAAGACAGAGAGATTGTAAATTGGAGTTTAGAAGTTACTGGAATTGCAGAATTTAAGG
ATAGAAATATGGAAGATTTATCAGGAGGACAAAGACAAAGGGCATGGATAGCTATGGCTTTGGCACAAGAAACTGATATA
TTATTACTGGATGAGCCTACAACATATTTAGATTTGGCACATCAATTGGAGATACTAAAATTATTAGATGAACTAAATAA
AAAACAAGGAAGAACTATTGTCATGGTAATACATGAACTTAATAATGCAGCAAGATTTGCTGACCACATGATAGGTATTA
AGAAAGGTAAAATAGTTTGTGAAGGTGATGCATATGATGTTATGACGAAAGATAATCTAAAAGAATTATTTAATATTGAT
GCAGAAATAGCAGCAGACCCAAGAACAAATAAACCAATTTGTATAACTTATGACATGGTGTAA

Protein sequence : 
MNCINTKNLNVSYGNTDIIKNLNLNIPKGKITTIIGANGCGKSTILKTIGRIISPNSGKIYINGEDIYKKKSKEIAKDMA
VLPQSPQAPSGLTVSELISYGRFPHKSGFGNSSKEDREIVNWSLEVTGIAEFKDRNMEDLSGGQRQRAWIAMALAQETDI
LLLDEPTTYLDLAHQLEILKLLDELNKKQGRTIVMVIHELNNAARFADHMIGIKKGKIVCEGDAYDVMTKDNLKELFNID
AEIAADPRTNKPICITYDMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SPN23F_09560 YP_002510939.1 ferric siderophore ABC transporter ATP-binding protein Virulence PPI-1 Protein 3e-55 47
SP_1035 NP_345510.1 iron-compound ABC transporter ATP-binding protein Not tested PPI-1 Protein 3e-55 47
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 3e-52 45
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 3e-52 45
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 2e-52 45
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 2e-52 45
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-56 44
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 3e-55 43
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-55 42
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-53 42
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-53 42
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-53 42
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-53 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC YP_001089388.1 ABC transporter ferrichrome-specific ATP-binding protein BAC0164 Protein 2e-55 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fhuC YP_001089388.1 ABC transporter ferrichrome-specific ATP-binding protein VFG1042 Protein 2e-55 43
fhuC YP_001089388.1 ABC transporter ferrichrome-specific ATP-binding protein VFG0925 Protein 2e-55 43