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Name : guaA (CD630_01980) Accession : YP_001086666.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.5.2 Position : 256539 - 258074 bp Length : 1536 bp Strand : + Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 1312531; Product type e : enzyme DNA sequence : ATGAAACATGAATTAGTACTTGTAATAGATTTTGGAGGACAATATAATCAGTTGATAGCTAGAAGAGTTAGAGAAAACAA CGTATATTGTGAAATACTTCCATGTACTGCAAGCATAGAAAGAATAAAAGAAAAAAATCCTAAAGGGATAATATTTACAG GCGGTCCAAATAGTGCGTATTTAGAAGATTCTCCAACAATATCAAAAGAAATATTTGAACTAGGAGTACCAATACTTGGA ATATGCTATGGTATTCAAATAATGTCTCATGTATTGGGTGGAGTTGTAAGAAAAGGTAATAAACAAGAAAAAGAATATGG AAAAACAGCTATAACTTATGGAAAATCATCATTATTTGAAGGAATAACTACAAATAGTGTATGGATGAGTCACACAGATT TAATAGAAAAAGTTCCAGAAGGATTTACTATAGTTGCAAATACTAATGATTGTCCAGTAGCAGCTATGGAAAATGTAGAA CGAAACCTATATGGAGTTCAATTCCATCCAGAGGTAGAACACTGTTTGGAAGGGGACAAGATACTTACAAACTTCTTATA TAATATTTGTAAAGTAAAAGGTGACTGGACTACAGATTCATTCATAGAAGATAAAATAAAAGAATTAAAAGAAAAAATAG GCGATAAAAAAGCTTTATGTGCTTTAAGTGGAGGAGTTGATTCTTCTGTTGCTGCAGTTCTTATTCATAAAGCAATTGGG GACAACTTAACTTGTATATTTGTTGACCATGGTTTACTTAGAAAAAATGAAGGAAATGATGTAGAAAGAATATTTAGAGA GAAATTTGATATAAATTTAATAAGAGTTAATGCAGAAGATAGATTCTTATCTAAATTAAAAGGAGTTTCTGAACCAGAAG CTAAGAGAAAAATAATAGGTGAAGAATTTATAAGAGTATTTGAAGAAGAATCAAATAAATTAGGAAAAATGGATTTCTTA GTACAAGGAACAATCTATCCAGATGTTATAGAAAGTGGACATGGAAATGCTGCTACTATAAAGTCTCATCATAATGTTGG TGGAATCCCAGAAGATGTAGACTTCCAAGAAATTGTAGAACCATTAAGAGAGTTATTTAAGGATGAAGTTAGAAAAATAG GATTAGAGCTTGGTATAGAAGAAGGATTAATATTTAGACATCCTTTCCCAGGACCAGGTCTAGGAATAAGAGTTATAGGT GATGTAACTAAAGAAAAATGTGATATATTAAGAGAAGCTGATGCTGTTTATATGGACGAGCTTAGAAAAGCAGGTTTATA TAGAGAAATATGGCAAGCTTTTGCAACATTACCAGATGTTAAGACTGTTGGAGTTATGGGTGATGAAAGAACATATGCTT ATTTAGTTGGTTTAAGAGCAGTTACTTCTTCTGATGGAATGACTTCTGACTGGTATAAGATGCCTTATGATGTATTAGAA AGAATTTCTAATAGAATAATAAATGAAGTTGATGGAGTAAATAGAGTAGTTTATGATATAACTTCTAAGCCTCCTGGAAC TATTGAATGGGAATAA Protein sequence : MKHELVLVIDFGGQYNQLIARRVRENNVYCEILPCTASIERIKEKNPKGIIFTGGPNSAYLEDSPTISKEIFELGVPILG ICYGIQIMSHVLGGVVRKGNKQEKEYGKTAITYGKSSLFEGITTNSVWMSHTDLIEKVPEGFTIVANTNDCPVAAMENVE RNLYGVQFHPEVEHCLEGDKILTNFLYNICKVKGDWTTDSFIEDKIKELKEKIGDKKALCALSGGVDSSVAAVLIHKAIG DNLTCIFVDHGLLRKNEGNDVERIFREKFDINLIRVNAEDRFLSKLKGVSEPEAKRKIIGEEFIRVFEEESNKLGKMDFL VQGTIYPDVIESGHGNAATIKSHHNVGGIPEDVDFQEIVEPLRELFKDEVRKIGLELGIEEGLIFRHPFPGPGLGIRVIG DVTKEKCDILREADAVYMDELRKAGLYREIWQAFATLPDVKTVGVMGDERTYAYLVGLRAVTSSDGMTSDWYKMPYDVLE RISNRIINEVDGVNRVVYDITSKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 3e-139 | 60 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 2e-139 | 60 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 1e-139 | 60 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 6e-130 | 53 |
