Gene Information

Name : leuS (CD630_25210)
Accession : YP_001089035.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Unknown
Product : leucyl-tRNA ligase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2913233 - 2915653 bp
Length : 2421 bp
Strand : -
Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 9387221, 18359782; Product type e : enzyme

DNA sequence :
ATGAGCGTATATAATTTTAAAGAAGTAGAATCGAAATGGCAAAAAATTTGGAAAGATAATAATCAGTATAAAATGGATAC
TGCACAAACTGAAAAACCTAATTATTACACATTAGAAATGTTCCCTTATCCATCTGGAAAAATACACATGGGACATGTTA
GAAATTATTCTATAGGTGATGTTGTCGCAAGATTCAAAAAAATGGAAGGATATAATGTACTTCATCCAATGGGATGGGAT
TCTTTTGGATTACCAGCTGAAAATGCAGCTATAAAACATGGGATACATCCGCATAAATGGACAATGGAAAATATAGAAGA
AATGAAAGAGCAATTAAATTTATTAGGTATTAGTTATGATTGGGATAAAGAAGTTGCAACTTCAACGCCAGAATACTATA
GATTTACACAAGAAATATTTTTGAAGTTTTTAGAGCATGGGCTTGCATATAAGAAAAAATCATATGTTAACTGGTGTCCT
TCTTGTGAGACTGTTCTTGCAAATGAGCAAGTTGTTCAAGGAGCATGTGAGAGATGTAAAGCAACAGTATTAAAGAAAGA
TTTAGAACAATGGTATTTTAAGACTACTGAATTTGCAGAAGAATTACTTAATGACTTAGATACATTAGATGGATGGCCAG
AAAAAGTTAAAACAATGCAAAAAAATTGGATAGGTAAAAGTACAGGAGCAGATTTAGTTTTTGATATAGATGGAACTGAT
AAATCTATGACAGTATTTACAACTAGACCAGACACAACTTATGGAGTTACTTATATGGTACTTGCTCCAGAGCATGAATT
AGTTAAAGAATTGGTTGCAGGGACTGAATATGAAGCAGATGTTGAAGCTTTTGTTCAAAAAATGCATACTATGACAGAAA
TAGAAAGAACAGCAGCTGATGTAGAAAAAGAAGGAATGTTTATAGGTAGATATGTTATAAATCCTTTAAATGGCAAGAAA
GTTCCTCTATGGATAGCTAACTATGTATTAGTTGAGTATGGAACGGGTGCTATAATGGCAGTTCCAGCACATGATGAAAG
AGATAGAGATTTTGCTGAAAAATATAATTTAGACATAATTGATGTAATAACAGAAGATAACAAAATGATAAATTCAGAAG
AATTTAATGGATTAGATGCTTCAGAAGGATTTGAAGGAATAATCGATAAGTTAGAAAAAGAAGGTAGAGGAAAGAGAACA
ATTAATTATAGACTTAGAGACTGGTTAGTTTCAAGACAAAGATACTGGGGTTGTCCTATACCTGTGGTTTATTGTGATGA
ATGTGGAATAGTTCCAGTTAAAAAGGAAGATTTACCAGTTCTTTTACCAACAGATGTTGAATTTACTGGAAAAGGGGAAT
CTCCACTTACGACTTCAAAGCAATTTATGTCAACAACTTGTCCTCACTGTGGAAAACCAGCTAGAAGGGAAGTTGATACT
ATGGATACATTCGTTGATTCTTCTTGGTATTTCTTAAGATATGTGGATAGCAATAATGAAAATGAACCATTTAGTAAGGA
ATTAGTTAATAGATGGCATCCAGTAGACCAATATATAGGTGGAGTAGAACATGCTATAATGCATTTGCTTTATGCAAGAT
GGTTTGTAAAGGCATTTAAGAGTATGGGAATGGTAGACTTCAATGAGCCATTTAAAAACTTACTTACTCAAGGAATGGTA
CTTATGGATGGTTCTAAAATGAGTAAGTCTAAAGGGAATACAGTATCTCCTATGGATATAATAGATGAGTATGGAGCAGA
TACTGCAAGACTTTTCGTATTATTTGCAGCACCACCAGAAAGAGATTTGGACTGGTCAGAGCAAGGTGTTGATGGATGCT
TTAGATTCTTAAATAGGGTTTATAGATTGGTTGACGAGTTAGCAGATGTGGTTAAAAAGGATGTAGAGTTTGGAGAATTA
AATTCCCAAGATAAGGATATGAGATATACTATACACTCTACACTTAAAAAAGTTACTGCTGATTTAAGTGAAAAATTCGG
ATTTAATACTGCTATATCAGCTCTTATGGAATTAATAAATGATATGTATAAATATAAAGAGTTAGATAATATAAACGAAG
CAGTTATAAAAGAAGGTGTACAAACTATAGTAACTATAATTGCACCATTTGCCCCTCATTTAGGTGAAGAACTATGGACT
ATGATAGGTAAAGAAGGAAGTGTATTTGATATAGACTGGCCTAAATATGACGAAAAAGCTTTAGTAAAAGATGAAATAGA
AGTTGTTGTACAAGTTAATGGAAAAGTTAGAGGAAAATTAACTGTTAACTCAAATATATCTAAAGATGAGATGGAAAAGG
TAGCTTTAGAAGATGAAAAAATAAAAGGATTAGTTGAAGGTAAAACTATAGTTAAAGTTGTAGCTGTACCTAAAAAACTA
GTAAATATAGTTGTTAAATAA

Protein sequence :
MSVYNFKEVESKWQKIWKDNNQYKMDTAQTEKPNYYTLEMFPYPSGKIHMGHVRNYSIGDVVARFKKMEGYNVLHPMGWD
SFGLPAENAAIKHGIHPHKWTMENIEEMKEQLNLLGISYDWDKEVATSTPEYYRFTQEIFLKFLEHGLAYKKKSYVNWCP
SCETVLANEQVVQGACERCKATVLKKDLEQWYFKTTEFAEELLNDLDTLDGWPEKVKTMQKNWIGKSTGADLVFDIDGTD
KSMTVFTTRPDTTYGVTYMVLAPEHELVKELVAGTEYEADVEAFVQKMHTMTEIERTAADVEKEGMFIGRYVINPLNGKK
VPLWIANYVLVEYGTGAIMAVPAHDERDRDFAEKYNLDIIDVITEDNKMINSEEFNGLDASEGFEGIIDKLEKEGRGKRT
INYRLRDWLVSRQRYWGCPIPVVYCDECGIVPVKKEDLPVLLPTDVEFTGKGESPLTTSKQFMSTTCPHCGKPARREVDT
MDTFVDSSWYFLRYVDSNNENEPFSKELVNRWHPVDQYIGGVEHAIMHLLYARWFVKAFKSMGMVDFNEPFKNLLTQGMV
LMDGSKMSKSKGNTVSPMDIIDEYGADTARLFVLFAAPPERDLDWSEQGVDGCFRFLNRVYRLVDELADVVKKDVEFGEL
NSQDKDMRYTIHSTLKKVTADLSEKFGFNTAISALMELINDMYKYKELDNINEAVIKEGVQTIVTIIAPFAPHLGEELWT
MIGKEGSVFDIDWPKYDEKALVKDEIEVVVQVNGKVRGKLTVNSNISKDEMEKVALEDEKIKGLVEGKTIVKVVAVPKKL
VNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 3e-175 45