Gene Information

Name : sat (CD630_22260)
Accession : YP_001088740.1
Strain : Clostridium difficile 630
Genome accession: NC_009089
Putative virulence/resistance : Resistance
Product : streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) (Vat(D))
Function : -
COG functional category : R : General function prediction only
COG ID : COG0110
EC number : 2.3.1.-
Position : 2576453 - 2577085 bp
Length : 633 bp
Strand : +
Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 12771141,10651391,8257133; Product type e : enzyme

DNA sequence : 
ATGACTATTCCAAGTTCAAATAAGGTATATCCAAGAAGTAATGATTATCAAACTGTATATCTTAAAAATGTAATAACAAG
GGAAAATATAGAAGTTGGAGATTACACAATATATAATGACTTTTATAATGACCCAAGAGATTTTGAGAAAAACAATGTAT
TGTATCATTACCCTATAAACAATGATAAATTAATAATTGGTAAGTTTTGCTCAATAGCATGTAATGCAAAATTTCTAATG
ACTAGTGGAAATCACTCAATGAAATCAAAATCCACATATACTTTTCCCATCTTTTATGAAGAATGGAAACTCGATATCAA
CCATATAACGGACGCTTGGGACAATAAGGGTAACATTATAATTGGAAATGATGTGTGGATAGGTTATGATTCTATAATTA
TGTCAGGTGTAAATATTGGTGATGGTGCAATTATTGGAACAAGAGCAGTAGTTACTAATGACGTTCCACCGTATTCTATT
GTTGGAGGAGTACCTGCAAAAATTATAAAAAAGAGATTTAATAATGATACAATTTCAAAATTATTAGAAATTAAATGGTG
GGATTGGCCATATAAAAAAATTCAATCAAACATTAAGCATATTCAATCAGGAAATATTGATAAATTAGTTTAA

Protein sequence : 
MTIPSSNKVYPRSNDYQTVYLKNVITRENIEVGDYTIYNDFYNDPRDFEKNNVLYHYPINNDKLIIGKFCSIACNAKFLM
TSGNHSMKSKSTYTFPIFYEEWKLDINHITDAWDNKGNIIIGNDVWIGYDSIIMSGVNIGDGAIIGTRAVVTNDVPPYSI
VGGVPAKIIKKRFNNDTISKLLEIKWWDWPYKKIQSNIKHIQSGNIDKLV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
catB3 AET25385.1 chloramphenicol acetyltransferase Not tested PAGI-2(C) Protein 4e-31 48
catB3 AFG30108.1 chloramphenicol acetyltransferase Not tested PAGI-2 Protein 4e-31 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
sat YP_001088740.1 streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) (Vat(D)) AM180355.1.gene2499. Protein 3e-93 100
sat YP_001088740.1 streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) (Vat(D)) AY740681.1.gene5.p01 Protein 2e-31 48
sat YP_001088740.1 streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) (Vat(D)) AF322577.2.gene4.p01 Protein 2e-31 48
sat YP_001088740.1 streptogramin A acetyltransferase (Virginiamycin acetyltransferase D) (Vat(D)) CP001581.1.gene990.p Protein 7e-31 42