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Name : CD630_21140 (CD630_21140) Accession : YP_001088628.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Resistance Product : two-component response regulator Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0745 EC number : - Position : 2443285 - 2443953 bp Length : 669 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 18689481, 18790863; Product type r : regulator DNA sequence : ATGAATTCGTCAATACTTGTAATTGAAGATGATTCAAATATACAAGAGTTAATATCAGAATTTTTAAGTGCAGAAGGTTA TCAAGTTGATACAGCAAATGATGGGTTGGAAGGTATACAAAAGTTTAAGCAAGGAAGTTATGATTTAGTCATATTAGATA TAATGATGCCAAACTTAGATGGTTATGGAGTTTGTAAAATGATAAGAAAGTCATCGAGCGTTCCAATTATATTTTTAACT GCTTTAAATGATGAAGGAGACCAACTTAAAGGGTTTGACTTAGAATGTGATGATTATATAACAAAACCATTTTCATTTAA TCTTCTTATAAAAAGAGTAGAAGCAATTTTAAGGCGAAGTAACAAGACTATAAATGACAAATTTATAGTTTTTGAAAAAT TAAAATTAGATTTAAACACATATATTGCAGAGATAGATGGAGAACCTATAGAACTTACACTAAAAGAGTTTAATATATTA AAAGCTTTGATAGAAAAGTATCCACAAGTTATAACTAGGGAAGGTCTTTTGGATAGTATATGGGGTTATGACTATTATGG AGATACTAGGATTGTTGATGCACATATAAAAAATATAAGAAAAAAAATATCATTACCATATATTAAAACTGTAAAAGGAA TAGGATATACACTTGAGAAGGATATTTGA Protein sequence : MNSSILVIEDDSNIQELISEFLSAEGYQVDTANDGLEGIQKFKQGSYDLVILDIMMPNLDGYGVCKMIRKSSSVPIIFLT ALNDEGDQLKGFDLECDDYITKPFSFNLLIKRVEAILRRSNKTINDKFIVFEKLKLDLNTYIAEIDGEPIELTLKEFNIL KALIEKYPQVITREGLLDSIWGYDYYGDTRIVDAHIKNIRKKISLPYIKTVKGIGYTLEKDI |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanRB | YP_001698483.1 | regulatory protein | Not tested | Not named | Protein | 9e-50 | 49 |
| vanRB | YP_008394254.1 | DNA-binding response regulator VanRB | Not tested | Not named | Protein | 1e-42 | 44 |
| vanRB | NP_815956.1 | DNA-binding response regulator VanRB | Not tested | Not named | Protein | 8e-42 | 43 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| CD630_21140 | YP_001088628.1 | two-component response regulator | HE999704.1.gene1202. | Protein | 4e-47 | 47 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | AF310956.2.orf0.gene | Protein | 5e-43 | 44 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | U35369.1.gene1.p01 | Protein | 3e-42 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | AE016830.1.gene2255. | Protein | 3e-42 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_002952.2859905.p0 | Protein | 7e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_003923.1003749.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_002758.1121668.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_009641.5332272.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_013450.8614421.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_007793.3914279.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_007622.3794472.p0 | Protein | 7e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_002745.1124361.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_009782.5559369.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_002951.3237708.p0 | Protein | 9e-36 | 43 |
| CD630_21140 | YP_001088628.1 | two-component response regulator | NC_012469.1.7685629. | Protein | 1e-36 | 42 |
