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Name : clpB (CD630_20200) Accession : YP_001088534.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Virulence Product : Chaperone protein Function : - COG functional category : O : Posttranslational modification, protein turnover, chaperones COG ID : COG0542 EC number : - Position : 2331406 - 2334000 bp Length : 2595 bp Strand : - Note : Evidence 2a : Function of homologous gene experimentally demonstrated in an other organism; PubMedId : 14762012; Product type f : factor DNA sequence : ATGGACGTAGAAAAAATGACTTTAAGAGTTCAAAAAAGTTTAAATGAGGCTTATAACGAAGCAGTAAAAAATCATAACCA ACAAGTAGATGTAATTCATCTTTTCTCAGCACTTATTAATCAAGAGGATGGATTGATACCAAATATAATCGAAAAAATGA ATATATCAATTGATTCTTTGAGAAATACTGTAAACTTTGAAATTGATAAGCTTCCAAAGGTATATGGAGAAGGTGCTGAC TCACAAGGAGTATCAGCTACTAGAAAAATAAATGAGGTGCTTATAAAGGCAGAGAGTATTTCTAAAGAATTTAAAGATTC ATATATAAGTGTAGAGCATGTTATGCTTGCAATGATGGAAACAGAATCAAAATCAGCTGTTGGTAAAATATTAAAACAAT ATAATATAAATAAGAATGACTTTTTAAATATTTTATCACAAGTGAGAGGTAGTCAAAGAGTAGAAACACAAGACCCAGAA GGCACATATGATGCACTTGCTAGATATGGAACAAACTTAGTAGATTTAGCCAAGAAAAATAAATTAGACCCTGTAATTGG GAGAGATGAAGAAATAAGAAGGATTATAAGAATTTTATCAAGAAGAACAAAAAATAATCCTGTATTGATTGGTGAGCCAG GTGTAGGTAAAACTGCAATTGTAGAAGGGTTAGCAGAGAGAATAGTAAGAGGAGACGTCCCAGAAGGTTTAAAAGATAAG ATTGTATTCTCACTTGATATGGGAGCTTTAATTGCTGGTGCAAAATATAGAGGTGAATTTGAAGAAAGATTAAAGGCAGT TTTAAAAGAAGTTCAAAGTTCTGATGGAAAAATTATACTGTTTATAGATGAGATTCATACTATTGTTGGAGCTGGTAAAA CAGAAGGTTCAATGGATGCAGGTAATCTTATTAAACCTATGCTTGCAAGAGGTGAATTGAACTGTATTGGTGCAACTACT TTTGATGAATATAGAAAGTATATAGAAAAAGATAAGGCTCTTGAAAGACGTTTTCAGCCTGTAATTGCAGAAGAACCTAC TGTTGAAGATACAATATCTATACTTAGAGGTTTAAAAGAAAGATTTGAGATACATCATGGAGTAAGAATACATGATAATG CTATTGTAGCAGCAGCAAAACTTTCTCATAGATATATACAAGATAGATTTTTACCAGATAAAGCAATTGATTTAATTGAT GAAGCTGGAGCTATGATTCGTAGTGAAATAGATTCATTGCCAACAGAATTAGATGTTGTTAGAAGAAAGTTATTTACATT AGAAACTGAAAGAGAAGCATTACTTAAAGAAAATGATGATAAAAGTAAATCAAGATTGGATGATATTCAAAAAGAAATAG CAGAGTTAAAATCTAAAAATGATGAAATGACAGCAAAATATGAAAAAGAAAAGAGTCAAATATTAGATATTAAAAACTTA AAGGCTCAATTAGACGAAGCTAAAGGTAAAGCTGAAAAGTATGAAAGAGAATATGATTTCAACAAAGCAGCAGAGGTTAA ATATGGGGAAATACCTAAGTTAGAAGAACAAATAAAGCAGTACGAAGAAAATATGAATGATGGTTCTGAAAATTCTCTTT TAAAAGAAGAAGTTACTGAAGAAGAAATATCTAGCATTGTATCAAAGTGGACAGGTATACCAGTAACTAAACTAGTTGAA GGAGAAAGAGAAAAATTACTTAAACTAGAAGATGAACTTCATAAAAGAGTTATTGGACAAGATGAAGCAGTTACAGCAGT TTCAAATGCAGTAATACGTGCAAGAGCAGGATTAAAAGATGAAAGAAAACCAATTGGTTCATTTATTTTCTTAGGCCCTA CAGGTGTTGGTAAAACTGAACTTGCAAAAACTCTTGCTAGAAATTTATTCGATAGTGAAGATAATATAATAAGAATAGAT ATGTCTGAATACATGGAAAAACATGCTGTATCAAGACTAGTTGGACCTCCTCCAGGGTACGTGGGATATGAAGAGGGTGG TCAACTTACAGAAGCAGTTAGACGTGCTCCTTATTCTGTAATACTATTTGATGAGATAGAAAAAGCACATGAGGATGTAT TTAACATGTTCTTACAGATATTAGATGATGGTAGACTTACTGATAATAAAGGTAAGACAGTAGACTTTAAAAATACTCTT ATAATAATGACTTCTAATATAGGAAGTAATTATCTATTAGAAGCAGGAGGAAATATAACAGAGACTACTAACAATTTAGT AATGAATGAAATGAAGCATAGATTTAAACCTGAGTTTTTAAACAGAGTAGATGATATTATAATGTTTAAGCCTTTAGACC AAGAAAATATCAAGAAAATTATAGATATATTTATGAAAGATTTAAAAAATAGATTAAAAGAAAAAGATATTACTATTGAA GTTACAAATTCAGCAAAAGATGTTATGGTGAGAGAAGGATATGACCCTGTATATGGAGCAAGACCTCTTAAGAGATATAT AGGAAATACATTAGAAACTATAATTGCAAAGAAACTTATTGCTGGAGATGTGTATAATGGATGTACTATAGTTATAGATG GAAAAGATGAAAATATTGAAGTTTTAGTTAAATAA Protein sequence : MDVEKMTLRVQKSLNEAYNEAVKNHNQQVDVIHLFSALINQEDGLIPNIIEKMNISIDSLRNTVNFEIDKLPKVYGEGAD SQGVSATRKINEVLIKAESISKEFKDSYISVEHVMLAMMETESKSAVGKILKQYNINKNDFLNILSQVRGSQRVETQDPE GTYDALARYGTNLVDLAKKNKLDPVIGRDEEIRRIIRILSRRTKNNPVLIGEPGVGKTAIVEGLAERIVRGDVPEGLKDK IVFSLDMGALIAGAKYRGEFEERLKAVLKEVQSSDGKIILFIDEIHTIVGAGKTEGSMDAGNLIKPMLARGELNCIGATT FDEYRKYIEKDKALERRFQPVIAEEPTVEDTISILRGLKERFEIHHGVRIHDNAIVAAAKLSHRYIQDRFLPDKAIDLID EAGAMIRSEIDSLPTELDVVRRKLFTLETEREALLKENDDKSKSRLDDIQKEIAELKSKNDEMTAKYEKEKSQILDIKNL KAQLDEAKGKAEKYEREYDFNKAAEVKYGEIPKLEEQIKQYEENMNDGSENSLLKEEVTEEEISSIVSKWTGIPVTKLVE GEREKLLKLEDELHKRVIGQDEAVTAVSNAVIRARAGLKDERKPIGSFIFLGPTGVGKTELAKTLARNLFDSEDNIIRID MSEYMEKHAVSRLVGPPPGYVGYEEGGQLTEAVRRAPYSVILFDEIEKAHEDVFNMFLQILDDGRLTDNKGKTVDFKNTL IIMTSNIGSNYLLEAGGNITETTNNLVMNEMKHRFKPEFLNRVDDIIMFKPLDQENIKKIIDIFMKDLKNRLKEKDITIE VTNSAKDVMVREGYDPVYGARPLKRYIGNTLETIIAKKLIAGDVYNGCTIVIDGKDENIEVLVK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| STY0294 | NP_454876.1 | ClpB-like protein | Not tested | SPI-6 | Protein | 2e-89 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| clpB | YP_001088534.1 | Chaperone protein | VFG2076 | Protein | 7e-86 | 41 |
