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Name : ermB (CD630_20070) Accession : YP_001088518.1 Strain : Clostridium difficile 630 Genome accession: NC_009089 Putative virulence/resistance : Resistance Product : ribosomal RNA adenine N-6-methyltransferase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0030 EC number : - Position : 2316967 - 2317704 bp Length : 738 bp Strand : - Note : Evidence 1c : Function experimentally demonstrated in the studied genus; PubMedId : 1513878, 7486927; Product type e : enzyme DNA sequence : ATGAACAAAAATATAAAATATTCTCAAAACTTTTTAACGAGTGAAAAAGTACTCAACCAAATAATAAAACAATTGAATTT AAAAGAAACCGATACCGTTTACGAAATTGGAACAGGTAAAGGGCATTTAACGACGAAACTGGCTAAAATAAGTAAACAGG TAACGTCTATTGAATTAGACAGTCATCTATTCAACTTATCGTCAGAAAAATTAAAACTGAATACTCGTGTCACTTTAATT CACCAAGATATTCTACAGTTTCAATTCCCTAACAAACAGAGGTATAAAATTGTTGGGAGTATTCCTTACCATTTAAGCAC ACAAATTATTAAAAAAGTGGTTTTTGAAAGCCGTGCGTCTGACATCTATCTGATTGTTGAAGAAGGATTCTACAAGCGTA CCTTGGATATTCACCGAACACTAGGGTTGCTCTTGCACACTCAAGTCTCGATTAAGCAATTGCTTAAGCTGCCAGCTGAA TGCTTTCATCCTAAACCAAAAGTAAACAGTGCCTTAATAAAACTTACCCGCCATACCACAGATGTTCCAGATAAATATTG GAAACTATATACGTACTTTGTTTCAAAATGGGTCAATCGAGAATATCGTCAACTGTTTACTAAAAATCAGTTTCATCAAG CAATGAAATACGCCAAAGTAAACGATTTAAGTACCGTTACTTATGAGCAAGTATTGTCTATTTTTAATAGTTATCTATTA TTTAACGGGAGGAAATAA Protein sequence : MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLTTKLAKISKQVTSIELDSHLFNLSSEKLKLNTRVTLI HQDILQFQFPNKQRYKIVGSIPYHLSTQIIKKVVFESRASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIKQLLKLPAE CFHPKPKVNSALIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKYAKVNDLSTVTYEQVLSIFNSYLL FNGRK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| ermA | BAC57474.1 | rRNA methylase | Not tested | Type-IIIinv SCCmec | Protein | 7e-53 | 51 |
| ermA | BAA82205.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-II SCCmec | Protein | 7e-53 | 51 |
| ermA1 | YP_039522.1 | rRNA adenine N-6-methyltransferase 1 | Not tested | Type-II SCCmec | Protein | 9e-53 | 51 |
| ermA | NP_370576.1 | rRNA methylase | Not tested | Type-II SCCmec | Protein | 9e-53 | 51 |
| ermA | NP_373288.1 | rRNA methylase | Not tested | Type-II SCCmec | Protein | 9e-53 | 51 |
| ermA-3 | YP_190052.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-II SCCmec | Protein | 9e-53 | 51 |
| unnamed | BAB47663.1 | rRNA adenine N-6-methyltransferase | Not tested | Type-III SCCmec | Protein | 2e-52 | 50 |
| unnamed | BAC53825.1 | rRNA adenine N-6-methyltransferase | Not tested | SRImec-III and SCCmec-III region | Protein | 2e-52 | 50 |
| ermC | NP_273130.1 | rRNA adenine N-6-methyltransferase | Not tested | IHT-A | Protein | 1e-56 | 50 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | AM180355.1.gene2259. | Protein | 1e-112 | 100 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | AM180355.1.gene2254. | Protein | 1e-112 | 100 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | AM903082.gene3.p01 | Protein | 6e-110 | 98 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | AM410044.gene14.p01 | Protein | 6e-110 | 98 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | M64090.gene.p01 | Protein | 2e-57 | 53 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | M15332.gene.p01 | Protein | 1e-52 | 52 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002745.1124852.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_009782.5559229.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002758.1120012.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002952.2859614.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002745.1122822.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002745.1124324.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002745.1125313.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | AJ313523.1.orf0.gene | Protein | 9e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_009782.5559087.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002758.1121630.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002952.2859615.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_002745.1123579.p0 | Protein | 4e-53 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | V01278.gene.p01 | Protein | 8e-58 | 51 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_007209.3523503.p0 | Protein | 6e-57 | 50 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_010686.6295746.p0 | Protein | 6e-57 | 50 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_007792.3912746.p0 | Protein | 2e-56 | 50 |
| ermB | YP_001088518.1 | ribosomal RNA adenine N-6-methyltransferase | NC_010685.6295744.p0 | Protein | 6e-57 | 50 |
